Basement membrane laminin‐5 is deposited in colorectal adenomas and carcinomas and serves as a ligand for α₃β₁ integrin

Induction of Cell Migration by Matrix Metalloprotease-2 Cleavage of Laminin-5

1997 • 1,227 citations

Regulation of development and differentiation by the extracellular matrix

1993 • 1,216 citations

Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes

1991 • 771 citations

Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments.

1991 • 755 citations

The Laminin α Chains: Expression, Developmental Transitions, and Chromosomal Locations of α1-5, Identification of Heterotrimeric Laminins 8–11, and Cloning of a Novel α3 Isoform

1997 • 661 citations

Type VII collagen is a major structural component of anchoring fibrils.

1986 • 545 citations

The function of multiple extracellular matrix receptors in mediating cell adhesion to extracellular matrix: preparation of monoclonal antibodies to the fibronectin receptor that specifically inhibit cell adhesion to fibronectin and react with platelet glycoproteins Ic-IIa.

1988 • 446 citations

Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines.

1984 • 424 citations

Laminin is produced by early rat astrocytes in primary culture.

1983 • 389 citations

Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas.

1995 • 383 citations

The anchoring filament protein kalinin is synthesized and secreted as a high molecular weight precursor.

1992 • 345 citations

A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody.

1987 • 334 citations

Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4.

1990 • 323 citations

Mapping of domains in human laminin using monoclonal antibodies: localization of the neurite-promoting site.

1986 • 318 citations

Cell surface antigens of human bladder cancer defined by mouse monoclonal antibodies.

1984 • 273 citations

The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers.

1994 • 271 citations

Human amnion contains a novel laminin variant, laminin 7, which like laminin 6, covalently associates with laminin 5 to promote stable epithelial-stromal attachment.

1996 • 264 citations

The Integrin α6β4 Functions in Carcinoma Cell Migration on Laminin-1 by Mediating the Formation and Stabilization of Actin-containing Motility Structures

1997 • 241 citations

The properdin-like type I repeats of human thrombospondin contain a cell attachment site.

1991 • 238 citations

Structure and assembly of hemidesmosomes

1998 • 224 citations

Presence of Laminin α5 Chain and Lack of Laminin α1 Chain during Human Muscle Development and in Muscular Dystrophies

1997 • 210 citations

Distinct and overlapping ligand specificities of the alpha 3A beta 1 and alpha 6A beta 1 integrins: recognition of laminin isoforms.

1994 • 204 citations

Monoclonal antibody and synthetic peptide inhibitors of human tumor cell migration.

1990 • 176 citations

Differential expression of laminin-5 subunits and integrin receptors in human colorectal neoplasia

1998 • 169 citations

Integrin α3β1-mediated interaction with laminin-5 stimulates adhesion, migration and invasion of malignant glioma cells

1998 • 166 citations

Domains of laminin

1996 • 158 citations

Diminished expression of integrin adhesion molecules on human colonic epithelial cells during the benign to malign tumour transformation.

1992 • 155 citations

Human colon carcinoma cells use multiple receptors to adhere to laminin: involvement of alpha 6 beta 4 and alpha 2 beta 1 integrins.

1990 • 127 citations

Anchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD protein.

1996 • 126 citations

Extracellular Matrix Components and Integrins in Relationship to Human Intestinal Epithelial Cell Differentiation

1997 • 117 citations

Epithelial integrins

1996 • 113 citations

Laminin-5 Expression Is Independent of the Injury and the Microenvironment During Reepithelialization of Wounds

1998 • 109 citations

Pancreatic carcinomas deposit laminin-5, preferably adhere to laminin-5, and migrate on the newly deposited basement membrane.

1997 • 109 citations

Differential expression of laminin 5 (alpha 3 beta 3 gamma 2) by human malignant and normal prostate.

1996 • 108 citations

Expression of laminin α1, α5 and β2 chains during embryogenesis of the kidney and vasculature

1996 • 104 citations

Human vascular endothelial cells express a membrane protein complex immunochemically indistinguishable from the platelet VLA-2 (glycoprotein Ia-IIa) complex

1989 • 92 citations

Receptors for laminins during epithelial morphogenesis

1996 • 91 citations

Alpha 6 beta 4 integrin and newly deposited laminin-1 and laminin-5 form the adhesion mechanism of gastric carcinoma. Continuous expression of laminins but not that of collagen VII is preserved in invasive parts of the carcinomas: implications for acquisition of the invading phenotype.

1996 • 87 citations

EXPRESSION OF THE LAMININ γ2 CHAIN IN PANCREATIC ADENOCARCINOMA

1996 • 84 citations

The M_r 140,000 fibronectin receptor complex in normal and virus‐transformed human fibroblasts and in fibrosarcoma cells: Identical localization and function

1989 • 79 citations

Inward growth of colonic adenomatous polyps

1996 • 78 citations

Anchoring complex components laminin-5 and type VII collagen in intestine: association with migrating and differentiating enterocytes.

1996 • 70 citations

Laminin and collagen IV subunit distribution in normal and neoplastic tissues of colorectum and breast

1997 • 69 citations

The Basement Membrane and Its Involvement in Carcinoma Cell Invasion

1995 • 69 citations

Human colonic cancer cells synthesize and adhere to laminin-5. Their adhesion to laminin-5 involves multiple receptors among which is integrin α2β1

1998 • 68 citations

Distinct changes in the laminin composition of basement membranes in human seminiferous tubules during development and degeneration.

1997 • 66 citations

Cloning and Expression of the Mouse Laminin gamma2 (B2t) Chain, a Subunit of Epithelial Cell Laminin

1995 • 62 citations

γ2 Chain of Laminin-5 Is Recognized By Monoclonal Antibody GB3

1995 • 60 citations

Morphogenesis of Minute Adenomas in Familial Polyposis Coli<xref ref-type="fn" rid="FN2">2</xref>

1984 • 58 citations

Expression and role of integrins in adhesion of human colonic carcinoma cells to extracellular matrix components

1991 • 52 citations

Differential expression of laminin chains and their integrin receptors in human gastric mucosa.

1995 • 47 citations

Laminins, tenascin and type VII collagen in colorectal mucosa

1996 • 46 citations

Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies

1992 • 45 citations

BeWo choriocarcinoma cells produce laminin 10

1998 • 43 citations

Immunoloealization of integrins in the normal and neoplastic colonic epithelium

1993 • 35 citations

Adhesive properties and integrin expression profiles of two colonic cancer populations differing by their spreading on laminin

1994 • 33 citations

The borderline: Basement membranes and the transition from premalignant to malignant neoplasia

1994 • 33 citations

Patterns and composition of basement membranes in colon adenomas and adenocarcinomas

1993 • 28 citations

Interconnection of integrins alpha 2 and alpha 3 and structure of the basal membrane in colorectal cancer: relation to survival.

1993 • 27 citations

Defective basement membrane in laryngeal carcinomas with heterogeneous loss of distinct components

1998 • 23 citations

Expression of beta 1 integrin in laminin-adhesion-selected human colon cancer cell lines of varying tumorigenicity.

1994 • 21 citations

Neoexpression of the epithelial adhesion complex antigens in thyroid tumours is associated with proliferation and squamous differentiation markers

1998 • 21 citations

Deleted Work

1955 • 0 citations