Biochemical actions of glucocorticoids on macrophages in culture. Specific inhibition of elastase, collagenase, and plasminogen activator secretion and effects on other metabolic functions.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The role of the macrophage in wound repair. A study with hydrocortisone and antimacrophage serum.

1975 • 1,445 citations

Glucocorticosteroid Therapy: Mechanisms of Action and Clinical Considerations

1976 • 1,035 citations

Corticosteroids and Lymphoid Cells

1972 • 1,030 citations

SECRETION OF PLASMINOGEN ACTIVATOR BY STIMULATED MACROPHAGES

1974 • 719 citations

Steroid Receptors: Elements for Modulation of Eukaryotic Transcription

1976 • 688 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

The Effect of In Vivo Hydrocortisone on Subpopulations of Human Lymphocytes

1974 • 607 citations

Inhibition of arachidonic acid release from cells as the biochemical action of anti-inflammatory corticosteroids.

1976 • 573 citations

Macrophages synthesise and release prostaglandins in response to inflammatory stimuli

1977 • 573 citations

Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells.

1976 • 555 citations

IN VITRO SYNTHESIS AND SECRETION OF LYSOZYME BY MONONUCLEAR PHAGOCYTES

1974 • 525 citations

Elastase secretion by stimulated macrophages. Characterization and regulation.

1975 • 522 citations

Secretion of a specific collagenase by stimulated macrophages.

1975 • 432 citations

Control of lymphokine secretion by prostaglandins

1976 • 415 citations

Macrophage plasminogen activator: Modulation of enzyme production by anti-inflammatory steroids, mitotic inhibitors, and cyclic nucleotides

1976 • 405 citations

INDUCTION OF MACROPHAGE PLASMINOGEN ACTIVATOR BY ENDOTOXIN STIMULATION AND PHAGOCYTOSIS

1974 • 330 citations

The separation, long-term cultivation, and maturation of the human monocyte.

1977 • 320 citations

Mechanisms of steroid resistance

1974 • 284 citations

THE EFFECT OF GLUCOCORTICOSTEROIDS ON THE KINETICS OF MONONUCLEAR PHAGOCYTES

1970 • 252 citations

GLUCOCORTICOID SUPPRESSION OF MACROPHAGE MIGRATION INHIBITORY FACTOR

1973 • 235 citations

Prostaglandin regulation of macrophage collagenase production.

1977 • 230 citations

Characterization of the factor in L‐cell conditioned medium capable of stimulating colony formation by mouse marrow cells in culture

1971 • 222 citations

Cultured human monocytes synthesize and secrete alpha2-macroglobulin.

1977 • 209 citations

Hydrocortisone inhibits prostaglandin production by mouse fibrosarcoma cells

1975 • 184 citations

Effect of corticosteroids on the human monocyte IgG and complement receptors.

1975 • 182 citations

Isolation of lymphoma cell variants resistant to killing by glucocorticoids

1974 • 176 citations

Glucocorticoid receptors and glucocorticoid sensitivity of mitogen stimulated and unstimulated human lymphocytes

1977 • 166 citations

Potentiation of erythropoiesis in vitro by dexamethasone.

1976 • 151 citations

Metabolic Site and Time Course of Cortisol Action on Glucose Uptake, Lactic Acid Output, and Glucose 6-Phosphate Levels of Rat Thymus Cells in Vitro

1968 • 148 citations

The interaction of estradiol-receptor protein with the genome: an argument for the existence of undetected specific sites

1975 • 144 citations

The Effects of Steroid Hormones on Macrophage Activity

1969 • 142 citations

THE EFFECT OF GLUCOCORTICOSTEROIDS ON THE PROLIFERATION AND KINETICS OF PROMONOCYTES AND MONOCYTES OF THE BONE MARROW

1973 • 136 citations

A study of macrophages and epitheloid-like cells from granulomatous (BCG-induced) lungs of rabbits.

1962 • 127 citations

THE ACTION OF CORTISONE ACETATE ON CELL-MEDIATED IMMUNITY TO INFECTION

1971 • 101 citations

Production of the second component of complement by human monocytes: stimulation by antigen-activated lymphocytes or lymphokines.

1977 • 97 citations

Regulation of human skin collagenase activity by hydrocortisone and dexamethasone in organ culture

1974 • 94 citations

The requirement of an adherent cell substratum for the growth of developing plasmacytoma cells in vivo.

1976 • 90 citations

Secretion of macrophage neutral proteinase is enhanced by colchicine.

1976 • 89 citations

Characterization of the Nonphagocytic Adherent Cell from the Peritoneal Cavity of Normal and BCG-Treated Mice

1977 • 77 citations

Effects of anti-inflammatory and other compounds on the release of lysosomal enzymes from macrophages

1975 • 76 citations

Effect of glucocorticosteroids on the phagocytosis and intracellular killing by peritoneal macrophages

1975 • 74 citations

Studies on steroid fever II. Pyrogenic and anti-pyrogenic activity in vitro of some endogenous steroids of man

1970 • 60 citations

Relationship between receptor and mammary tumour virus production after stimulation by glucocorticoid

1976 • 53 citations

COMPARATIVE EFFECTS OF CORTICOSTEROIDS ON HOST RESISTANCE TO INFECTION IN RELATION TO CHEMICAL STRUCTURE

1967 • 50 citations

Cortisone Action on Serum Colony-Stimulating Factor and Bone Marrow in Vitro Colony-Forming Cells

1969 • 50 citations

The in vitro effect of hydrocortisone on the uptake and intracellular digestion of particulate matter by macrophages in culture.

1972 • 45 citations

Inhibition of murine granulopoiesis in vitro by dexamethasone

1976 • 43 citations

The role of transcortin in glucocorticoid mediated enzyme induction: Tyrosine aminotransferase induction in hepatoma tissue culture cells

1974 • 36 citations

Inhibition by hydrocortison of plasminogen activator production in rat tongue organ cultures.

1974 • 29 citations

Generation of macrophage migration inhibitory activity by plasminogen activators.

1977 • 22 citations

Action of betamethasone disodium phosphate on the metabolism of collagen and noncollagen protein in rat carrageenin granuloma

1972 • 21 citations

Effect of Methylprednisolone on some BCG-Mediated Changes in Rabbit Alveolar Macrophage

1972 • 6 citations