Effects of anti-inflammatory and other compounds on the release of lysosomal enzymes from macrophages

Experimental Immunochemistry

1962 • 1,576 citations

The interaction of α2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

1973 • 1,062 citations

Effects of Anti-inflammatory Drugs on Prostaglandin Biosynthesis

1972 • 478 citations

MECHANISMS OF LYSOSOMAL ENZYME RELEASE FROM LEUKOCYTES EXPOSED TO IMMUNE COMPLEXES AND OTHER PARTICLES

1971 • 439 citations

Mechanism of Immunologically Specific Killing of Tumour Cells by Macrophages

1972 • 435 citations

The action of steroids and streptolysin S on the permeability of phospholipid structures to cations

1965 • 395 citations

Lysosomes, a Laboratory Handbook

1973 • 383 citations

Effect of Cyclic AMP on Release of Lysosomal Enzymes from Phagocytes

1971 • 380 citations

MECHANISMS OF LYSOSOMAL ENZYME RELEASE FROM HUMAN LEUKOCYTES

1973 • 346 citations

The Interaction of Drugs and Subcellular Components in Animal Cells

1969 • 331 citations

Prostaglandins in Cellular Biology

1972 • 260 citations

Release of lysosomal protease by ultraviolet irradiation and inhibition by hydrocortisone

1961 • 258 citations

Membrane Stabilization by Drugs: Tranquilizers, Steroids, and Anesthetics

1966 • 234 citations

Studies on the Pathogenesis of Rheumatoid Joint Inflammation

1965 • 218 citations

Immune Complexes induce Selective Release of Lysosomal Hydrolases from Macrophages

1974 • 173 citations

Some Physical and Chemical Properties of Concanavalin A, the Phytohemagglutinin of the Jack Bean^*

1967 • 165 citations

Effects of anti-inflammatory drugs on the stability of rat liver lysosomes in vitro

1971 • 133 citations

Effects of Drugs on Cellular Control Mechanisms

1971 • 102 citations

Characteristics and isolation of the phagocytosis-stimulating peptide, tuftsin

1973 • 90 citations

Suppression of enzyme release from isolated rat liver lysosomes by non-steroidal anti-inflammatory drugs

1968 • 89 citations

A comparison of the duration of local anti-inflammatory effect of several adrenocorticosteroid esters--a bioassay technique.

1963 • 88 citations

Mobilization and extracellular release of granular enzymes from human leukocytes during phagocytosis: inhibition by colchicine and cortisol but not by salicylate

1973 • 81 citations

Microassay for cathepsin D shows an unexpected effect of cycloheximide on limb-bone rudiments in organ culture

1970 • 78 citations

Effect of Concanavalin A on Phagocytosis

1972 • 75 citations

Enzyme release from human leukocytes and degradation of cartilage matrix effects of antirheumatic drugs

1974 • 61 citations

Dissimilar effects of anti-inflammatory drugs on stability of lysosomes from peritoneal and circulating leukocytes and liver

1971 • 54 citations

Inhibition by pepstatin of human cartilage degradation

1972 • 52 citations

Enzyme Release from Guinea-pig Polymorphonuclear Leucocyte Lysosomes Inhibited in vitro by Anti-Inflammatory Drugs

1972 • 50 citations

Changes in liver lysosome fragility, erythrocyte membrane stability, and local and systemic lysosomal enzyme levels in adjuvant-induced polyarthritis

1972 • 45 citations

Effects of prostaglandins on release of enzymes from lysosomes of pancreas, spleen and kidney cortex

1973 • 43 citations

Nonphagocytic release of neutral protease and β‐glucuronidase from human neutrophils regulation by autonomic neurohormones and cyclic neucleotides

1974 • 41 citations

Effect of adenosine triphosphate and some anti-inflammatory agents on a purified lysosomal fraction having high acid phosphatase and labile β-glucuronidase activity

1971 • 38 citations

Selective release of lysosomal hydrolases from phagocytic cells by cytochalasin B

1973 • 37 citations

Concentration of Cyclic Adenosine 3′,5′ -Monophosphate in Human Leucocytes during Phagocytosis

1971 • 34 citations

Linoleic Acid Hydroperoxide: Impaired Bacterial Uptake by Alveolar Macrophages, a Mechanism of Oxidant Lung Injury

1973 • 26 citations

Preservation of structural integrity of liver lysosomes and membrane-stabilizing action of anti-inflammatory drugs, catecholamines and cyclic adenosine monophosphate in isotonic salt media

1973 • 23 citations

The in vitro effect of hydrocortisone on cultures of peritoneal monocytes.

1969 • 19 citations

Biochemical studies on the effect of papaverine on polymorphonuclear leucocytes

1973 • 10 citations

Primary Screening Approach for Anti-Inflammatory Agents Utilizing an In Vivo and a New In Vitro Method

1972 • 4 citations