Tumour cells surviving in vivo cisplatin chemotherapy display elevated c-myc expression

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Statistical Methods for Psychology.

1994 • 8,414 citations

Antisense Oligonucleotides as Therapeutic Agents—Is the Bullet Really Magical?

1993 • 1,306 citations

High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis.

1992 • 912 citations

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

1992 • 871 citations

Mediation of c-Myc-Induced Apoptosis by p53

1994 • 741 citations

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

1987 • 696 citations

Control of c-myc Regulation in Normal and Neoplastic Cells

1991 • 632 citations

Cellular accumulation of the anticancer agent cisplatin: A review

1993 • 557 citations

Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer

1993 • 421 citations

Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance.

1990 • 393 citations

Max: functional domains and interaction with c-Myc.

1992 • 280 citations

Regulation by bcl-2, c-myc, and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation-competent and -defective myeloid leukemic cells.

1993 • 280 citations

Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin

1992 • 240 citations

Inhibitory effects of antisense oligodeoxynucleotides targeting c-myc mRNA on smooth muscle cell proliferation and migration.

1993 • 165 citations

Effects of c-myc Expression on Cell Cycle Progression

1994 • 141 citations

Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates.

1992 • 122 citations

A FOS protein is present in a complex that binds a negative regulator of MYC.

1989 • 106 citations

Effects of c-myc expression on proliferation, quiescence, and the G0 to G1 transition in nontransformed cells.

1993 • 105 citations

Elevated expression of thymidylate synthase cycle genes in cisplatin-resistant human ovarian carcinoma A2780 cells.

1988 • 98 citations

In vivo studies with phosphorothioate oligonucleotides: pharmacokinetics prologue.

1991 • 96 citations

Resistance to anticancer drugs in NIH3T3 cells transfected with c-myc and/or c-H-ras genes

1991 • 90 citations

Characterization of rat c-mycand adjacent regions

1987 • 90 citations

Over-expression of the c-myc proto-oncogene in colorectal carcinoma

1993 • 88 citations

Expression of the c-Ha-ras oncogene in mouse NIH 3T3 cells induces resistance to cisplatin.

1991 • 86 citations

Relationship of c-myc Amplification to Progression of Breast Cancer From In Situ to Invasive Tumor and Lymph Node Metastasis

1993 • 84 citations

Modulation of cis-platinum resistance in Friend erythroleukemia cells by c-myc.

1991 • 81 citations

c‐myc over‐expression in human primary ovarian tumours: Its relevance to tumour progression

1992 • 74 citations

Enhancement of sensitivity of urinary bladder tumor cells to cisplatin by c-myc antisense oligonucleotide

1994 • 73 citations

cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway.

1992 • 72 citations

Antisense c-myc effects on preimplantation mouse embryo development.

1992 • 63 citations

In vitro modulation of cisplatin accumulation in human ovarian carcinoma cells by pharmacologic alteration of microtubules.

1993 • 54 citations

Detection of the c‐myc Gene Product in Urinary Bladder Cancer

1990 • 52 citations

The utility of an antifos ribozyme in reversing cisplatin resistance in human carcinomas

1992 • 51 citations

Pleiotropic-resistant phenotype is a multifactorial phenomenon in human colon carcinoma cell lines

1991 • 50 citations

Tumour cells surviving in vivo cisplatin chemotherapy display elevated c-myc expression

1996 • 42 citations

Differential oncogene amplification in tumor cells from a patient treated with cisplatin and 5-fluorouracil

1990 • 39 citations

Radiation response of human lung cancer cells with inherent and acquired resistance to cisplatin

1991 • 39 citations

Expression of oncoproteins in primary human non-small cell lung cancer and incidence of metastases

1993 • 38 citations

G1 phase chinese hamster V79-379A cells are inherently more sensitive to platinum bound to their dna than mid S phase or asynchronously treated cells

1979 • 34 citations

Radiation-induced transient cisplatin resistance in murine fibrosarcoma cells associated with elevated metallothionein content

1993 • 25 citations

Cisplatin as a radiation sensitizer in the treatment of advanced head and neck cancers. Results of a phase II study

1994 • 24 citations

Gene expression in X-irradiated human tumour cell lines expressing cisplatin resistance and altered DNA repair capacity

1994 • 13 citations

Dose response and toxicity of doxorubicin microspheres in a rat tumor model

1992 • 12 citations

Multifactorial molecular mechanisms are involved in resistance of preirradiated human cervix carcinoma cells to cis-dichlorodiammineplatinum (II) and vincristine.

1993 • 10 citations

Cis-platin responsive sequences in the human c-myc promoter.

1991 • 8 citations

Efficacy of ion-exchange resins for anti-tumour drug delivery

1990 • 4 citations

Coordinate change of c-myc, transferrin receptor and H3 gene expression precedes induction of haemoglobin-producing cells of the leukaemia K562 cell line treated with cis-diamminedichloroplatinum (II).

1991 • 4 citations

Current status of intraperitoneal therapy for ovarian cancer

1993 • 4 citations

EFFECTS OF C-MYC ANTISENSE TRANSCRIPTS ON DIFFERENTIATION OF K562 CELLS

1995 • 2 citations