In vitro modulation of cisplatin accumulation in human ovarian carcinoma cells by pharmacologic alteration of microtubules.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A gas-liquid solid phase peptide and protein sequenator.

1981 • 2,238 citations

Stereological Methods. Practical methods for biological morphometry

1979 • 2,038 citations

Taxol: A Unique Antineoplastic Agent with Significant Activity in Advanced Ovarian Epithelial Neoplasms

1989 • 1,111 citations

Isolation of human‐p53‐specific monoclonal antibodies and their use in the studies of human p53 expression

1986 • 508 citations

Phosphorylation determines two distinct species of tau in the central nervous system

1987 • 405 citations

Identification of conserved isotype-defining variable region sequences for four vertebrate beta tubulin polypeptide classes.

1986 • 403 citations

Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance.

1990 • 393 citations

10-nm filaments are induced to collapse in living cells microinjected with monoclonal and polyclonal antibodies against tubulin.

1984 • 388 citations

Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol.

1988 • 372 citations

Short-termcis-diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells

1990 • 357 citations

Characterization of the adducts produced in DNA by cis-diamminedichloroplatinum(II) and cis-dichloro(ethylenediamine)platinum(II)

1983 • 329 citations

Differences in the cellular distributions of two microtubule-associated proteins, MAP1 and MAP2, in rat brain

1984 • 326 citations

Resistance to antimitotic drugs in Chinese hamster ovary cells correlates with changes in the level of polymerized tubulin

1991 • 225 citations

Increased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human ovarian cancer cell lines.

1992 • 197 citations

Phase I and pharmacodynamic study of taxol in refractory acute leukemias.

1989 • 196 citations

Differential potentiation of alkylating and platinating agent cytotoxicity in human ovarian carcinoma cells by glutathione depletion.

1985 • 195 citations

Cell-mediated immunity to human malignant cells

1972 • 148 citations

Rapid Emergence of Acquired cis-Diamminedichloroplatinum(II) Resistance in an In Vivo Model of Human Ovarian Carcinoma

1990 • 134 citations

Phenotypic consequences of tubulin overproduction in Saccharomyces cerevisiae: differences between alpha-tubulin and beta-tubulin.

1990 • 131 citations

Monoclonal antibodies that recognize discrete forms of tubulin.

1982 • 113 citations

Subcellular distribution of enzymes determined by rapid digitonin fractionation of isolated hepatocytes

1980 • 96 citations

Modulation of cis‐diamminedichloroplatinum(II) accumulation and sensitivity by forskolin and 3‐isobutyl‐1‐methylxanthine in sensitive and resistant human ovarian carcinoma cells

1991 • 93 citations

Activation of adenylate cyclase and inhibition of glucose transport in rat adipocytes by forskolin analogues: structural determinants for distinct sites of action.

1988 • 85 citations

Refractoriness to chemotherapy and poor survival related to abnormalities of chromosomes 17 and 7 in lymphoma

1989 • 75 citations

Mechanisms by which mammalian cells acquire resistance to drugs that affect microtubule assembly

1989 • 75 citations

Single d(ApG)/cis-diamminedichloroplatinum(II) adduct-induced mutagenesis in Escherichia coli.

1990 • 53 citations

Phenotypic Consequences of Tubulin Overproduction in Saccharomyces cerevisiae: Differences between Alpha-Tubulin and Beta-Tubulin

1990 • 48 citations

Antitubulin antibodies. II. Natural autoantibodies and induced antibodies recognize different epitopes on the tubulin molecule.

1988 • 47 citations

Simian virus 40 large T antigen and p53 are microtubule-associated proteins in transformed cells.

1991 • 44 citations

[4] Measurement of hormone-stimulated protein phosphorylation in intact cells

1983 • 44 citations

In vitro mechanism study of microtubule assembly inhibition by cis-dichlorodiammine-platinum(II)

1986 • 36 citations

Changes in the cytoskeleton pattern of tumor cells by cisplatin in vitro

1992 • 36 citations

cis-Diamminedichloroplatinum (II) (cisplatin) alters microtubule assembly dynamics

1992 • 36 citations

The mutagenic and carcinogenic properties of three second generation antitumour platinum compounds: a comparison with cisplatin

1989 • 30 citations

Increased Gene-Specific Repair of Cisplatin Interstrand Cross-Links in Cisplatin-Resistant Human Ovarian Cancer Cell Lines

1992 • 18 citations

Effects of cisplatin on human thyrocytes in monolayer or follicle culture

1992 • 16 citations

Mammalian brain microtubules are sensitive to cyclic AMP in Vitro

1984 • 8 citations

Biochemical Modulation of Cisplatin

1988 • 7 citations