Matrix metalloproteinases and their tissue inhibitors in pressure-overloaded human myocardium during heart failure progression

The Soluble Catalytic Domain of Membrane Type 1 Matrix Metalloproteinase Cleaves the Propeptide of Progelatinase A and Initiates Autoproteolytic Activation

1996 • 564 citations

Molecular Cloning and Characterization of Human Tissue Inhibitor of Metalloproteinase 4

1996 • 547 citations

Gene Expression in Fibroblasts and Fibrosis

2002 • 508 citations

A Matrix Metalloproteinase Induction/Activation System Exists in the Human Left Ventricular Myocardium and Is Upregulated in Heart Failure

2000 • 470 citations

Differential Expression of Tissue Inhibitors of Metalloproteinases in the Failing Human Heart

1998 • 376 citations

Time-Dependent Changes in Matrix Metalloproteinase Activity and Expression During the Progression of Congestive Heart Failure

1998 • 372 citations

Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat

2000 • 293 citations

Fibrosis of the left atria during progression of heart failure is associated with increased matrix metalloproteinases in the rat

2003 • 190 citations

Excessive activation of matrix metalloproteinases coincides with left ventricular remodeling during transition from hypertrophy to heart failure in hypertensive rats

2002 • 142 citations

Cardiac remodelling in end stage heart failure: upregulation of matrix metalloproteinase (MMP) irrespective of the underlying disease, and evidence for a direct inhibitory effect of ACE inhibitors on MMP

2002 • 138 citations

MMP/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACE- and MMP-inhibition

2000 • 136 citations

Differential effects of pressure or volume overload on myocardial MMP levels and inhibitory control

2000 • 128 citations

Temporal regulation of extracellular matrix components in transition from compensatory hypertrophy to decompensatory heart failure

1999 • 122 citations

Cell cycle-associated accumulation of tissue inhibitor of metalloproteinases-1 (TIMP-1) in the nuclei of human gingival fibroblasts

1998 • 98 citations

MMP inhibition modulates TNF-α transgenic mouse phenotype early in the development of heart failure

2002 • 74 citations

Expression of Matrix Metalloproteinases in Patients With Acute Myocardial Infarction

2001 • 70 citations

Activation of gelatinase–tissue-inhibitors-of-metalloproteinase complexes by matrilysin

1998 • 68 citations

Regression of Left Ventricular Hypertrophy After Surgical Therapy for Aortic Stenosis Is Associated With Changes in Extracellular Matrix Gene Expression

2001 • 53 citations

Changes in collagen metabolism in response to endothelin-1: Evidence for fibroblast heterogeneity

1996 • 46 citations

Matrix metalloproteinases and tissue inhibitors of metalloproteinases in hamster aortic atherosclerosis: correlation with in-situ zymography

2002 • 33 citations

Fibroblast subpopulations in intra‐oral wound healing

2003 • 23 citations

Defects in Matrix Metalloproteinase Inhibitory Stoichiometry and Selective MMP Induction in Patients with Nonischemic or Ischemic Dilated Cardiomyopathy

1999 • 19 citations

Remodeling der extrazellulären Matrix bei dilatativer Kardiomyopathie

2002 • 18 citations

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