Use of vaccinia virus vectors to study protein processing in human disease. Normal nerve growth factor processing and secretion in cultured fibroblasts from patients with familial dysautonomia.

Physiology of nerve growth factor.

1980 • 1,602 citations

Destruction of the sympathetic ganglia in mammals by an antiserum to a nerve-growth protein

1960 • 651 citations

POLYPROTEIN GENE EXPRESSION: Generation of Diversity of Neuroendocrine Peptides

1984 • 497 citations

Trafficking of lysosomal enzymes in normal and disease states.

1986 • 445 citations

Mutation of Antitrypsin to Antithrombin

1983 • 430 citations

Purification and characterization of enkephalin convertase, an enkephalin-synthesizing carboxypeptidase.

1983 • 265 citations

Experimental autoimmune model of nerve growth factor deprivation: Effects on developing peripheral sympathetic and sensory neurons

1979 • 220 citations

Reversible dissociation of the mouse nerve growth factor protein into different subunits

1968 • 210 citations

Quantitative studies of dorsal root ganglia and neuropathologic observations on spinal cords in familial dysautonomia

1978 • 142 citations

Processing of the native nerve growth factor precursor to form biologically active nerve growth factor.

1988 • 139 citations

Differential RNA splicing predicts two distinct nerve growth factor precursors

1986 • 136 citations

Quantitative studies of sympathetic ganglia and spinal cord intermedio-lateral gray columns in familial dysautonomia

1978 • 127 citations

Enzymatic activities of mouse nerve growth factor and its subunits.

1968 • 100 citations

Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions

1985 • 89 citations

Expression and Cell Type—Specific Processing of Human Preproenkephalin with a Vaccinia Recombinant

1986 • 81 citations

Quantitative studies of ciliary and sphenopalatine ganglia in familial dysautonomia

1978 • 81 citations

Altered nerve growth factor in fibroblasts from patients with familial dysautonomia.

1980 • 69 citations

Peroxisomal organization in normal and cerebrohepatorenal (Zellweger) syndrome fibroblasts.

1985 • 60 citations

Increased Nerve-Growth-Factor β-Chain Cross-Reacting Material in Familial Dysautonomia

1976 • 48 citations

The alpha-subunit of mouse 7 S nerve growth factor is an inactive serine protease.

1984 • 47 citations

Nonpolarized expression of a secreted murine leukemia virus glycoprotein in polarized epithelial cells

1986 • 46 citations

Structural gene for beta-nerve growth factor not defective in familial dysautonomia.

1984 • 44 citations

Nerve growth factor synthesized by mouse fibroblast cells in culture: absence of .alpha. and .gamma. subunits

1983 • 38 citations

Decreased noradrenaline (norepinephrine) synthesis in familial dysautonomia

1971 • 34 citations

Polyprotein Gene Expression: Generation of Diversity of Neuroendocrine Peptides

1984 • 31 citations

Absence of the α and γ subunits of 7S nerve growth factor in denervated rodent iris: Immunocytochemical studies

1986 • 29 citations