Expression and Cell Type—Specific Processing of Human Preproenkephalin with a Vaccinia Recombinant

Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA

1982 • 672 citations

Vaccinia virus: a selectable eukaryotic cloning and expression vector.

1982 • 663 citations

Post-Translational Proteolysis in Polypeptide Hormone Biosynthesis

1982 • 590 citations

Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus.

1982 • 506 citations

POLYPROTEIN GENE EXPRESSION: Generation of Diversity of Neuroendocrine Peptides

1984 • 497 citations

Expression of rabies virus glycoprotein from a recombinant vaccinia virus

1984 • 448 citations

Two distinct intracellular pathways transport secretory and membrane glycoproteins to the surface of pituitary tumor cells

1982 • 340 citations

Expressing a human proinsulin cDNA in a mouse ACTH-secreting cell. Intracellular storage, proteolytic processing, and secretion on stimulation

1983 • 329 citations

Construction and characterization of an infectious vaccinia virus recombinant that expresses the influenza hemagglutinin gene and induces resistance to influenza virus infection in hamsters.

1983 • 296 citations

Biochemistry of the enkephalins and enkephalin-containing peptides

1983 • 270 citations

An About 50,000-Dalton Protein in Adrenal Medulla: a Common Precursor of [Met]- and [Leu]Enkephalin

1980 • 265 citations

Processing of Proenkephalin Is Tissue-Specific

1984 • 134 citations

Hybridization in Situ of SV40 Plaques: Detection of Recombinant Sv40 Virus Carrying Specific Sequences of Nonviral DNA

1977 • 108 citations

Expression of preprosomatostatin in heterologous cells: Biosynthesis, posttranslational processing, and secretion of mature somatostatin

1984 • 96 citations

Expression of simian virus 40-rat preproinsulin recombinants in monkey kidney cells: use of preproinsulin RNA processing signals.

1981 • 94 citations

Selective packaging of human growth hormone into synaptic vesicles in a rat neuronal (PC12) cell line.

1985 • 94 citations

Secretion of human parathyroid hormone from rat pituitary cells infected with a recombinant retrovirus encoding preproparathyroid hormone.

1984 • 92 citations

Active γ-carboxylated human factor IX expressed using recombinant DNA techniques

1985 • 91 citations

Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions

1985 • 89 citations

[19] Sensitive detection of proteins and peptides in polyacrylamide gels after formaldehyde fixation

1983 • 82 citations

The exocrine protein trypsinogen is targeted into the secretory granules of an endocrine cell line: studies by gene transfer.

1985 • 82 citations

Expression of the human insulin gene and cDNA in a heterologous mammalian system.

1983 • 77 citations

Expression of the human proenkephalin gene in mouse pituitary cells: accurate and efficient mRNA production and proteolytic processing.

1985 • 69 citations