Characterization of the interaction of transformed rat hepatic cytosolic Ah receptor with a dioxin responsive transcriptional enhancer

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

1982 • 2,512 citations

Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.

1976 • 1,343 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

Comparative Toxicology and Mechanism of Action of Polychlorinated Dibenzo-P-Dioxins and Dibenzofurans

1986 • 707 citations

The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci

1989 • 609 citations

The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain

1988 • 522 citations

Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor

1987 • 512 citations

Association of the Ah receptor with the 90-kDa heat shock protein.

1988 • 511 citations

Preferential Heterodimer Formation by Isolated Leucine Zippers from Fos and Jun

1989 • 469 citations

The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis.

1988 • 455 citations

A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor.

1986 • 412 citations

Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation.

1979 • 401 citations

The general affinity of lac repressor for E. coli DNA: Implications for gene regulation in procaryotes and eucaryotes

1975 • 341 citations

The Regulation of Cytochrome P-450 Gene Expression

1986 • 283 citations

Separation of the hormone- and DNA-binding sites of the hepatic glucocorticoid receptor by means of proteolysis.

1978 • 258 citations

The regulation of gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

1987 • 251 citations

Genetic Expression of Aryl Hydrocarbon Hydroxylase by 2,3,7,8-Tetrachlorodibenzo-p-dioxin: Evidence for a Receptor Mutation in Genetically Non-responsive Mice

1975 • 238 citations

Association of the dioxin receptor with the Mr 90,000 heat shock protein: A structural kinship with the glucocorticoid receptor

1988 • 234 citations

Protein-DNA Interactions at Recognition Sites for the Dioxin-Ah Receptor Complex

1989 • 215 citations

The "activated" hepatic glucocorticoid-receptor complex. Its generation and properties.

1975 • 213 citations

Steroid hormone receptors : structure and function

1983 • 210 citations

The Ah locus: Correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA

1982 • 184 citations

Domains of the Glucocorticoid Receptor Involved in Specific and Nonspecific Deoxyribonucleic Acid Binding, Hormone Activation, and Transcriptional Enhancement

1987 • 174 citations

Structure and function of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols.

1986 • 168 citations

The examination and quantitation of tissue cytosolic receptors for 2,3,7,8-tetrachlorodibenzo-p-dioxin using hydroxylapatite

1982 • 168 citations

Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins.

1989 • 164 citations

The Purified Activated Glucocorticoid Receptor is a Homodimer

1989 • 156 citations

Kinetic and equilibrium studies of Ah receptor-ligand binding: use of [125I]2-iodo-7,8-dibromodibenzo-p-dioxin.

1988 • 97 citations

Comparison of the flanking regions and introns of the mouse 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 and P3-450 genes.

1985 • 96 citations

Characterization of multiple forms of the Ah receptor: comparison of species and tissues

1989 • 85 citations

Photoaffinity labeling and partial proteolysis of wild-type and variant glucocorticoid receptors

1983 • 74 citations

Physicochemical characterization of specific and nonspecific polyaromatic hydrocarbon binders in rat and mouse liver cytosol.

1983 • 73 citations

Physicochemical characterization of the nuclear form of Ah receptor from mouse hepatoma cells exposed in culture to 2,3,7,8-tetrachlorodibenzo-p-dioxin

1988 • 71 citations

Heterogeneity of the rat hepatic Ah receptor and evidence for transformation in vitro and in vivo.

1987 • 67 citations

The binding activity of estrogen receptor to DNA and heat shock protein (Mr 90,000) is dependent on receptor-bound metal.

1987 • 66 citations

The Woolf plot is more reliable than the Scatchard plot in analysing data from hormone receptor assays

1980 • 65 citations

Zinc potentiation of androgen receptor binding to nuclei in vitro

1984 • 61 citations

Identification of the Ah receptor in selected mammalian species and induction of aryl hydrocarbon hydroxylase

1985 • 59 citations

Hepatic Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Partial stabilization by molybdate.

1986 • 54 citations

Activation of the dioxin and glucocorticoid receptors to a DNA binding state under cell-free conditions.

1990 • 51 citations

The binding of transformed aromatic hydrocarbon (Ah) receptor to its DNA recognition site is not affected by metal depletion

1990 • 42 citations

Characterization of the DNA-binding properties of the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin

1986 • 36 citations

The induction of cytochrome P-450 by isosafrole and related methylenedioxyphenyl compounds

1985 • 36 citations

The hepatic Ah receptor for 2,3,7,8-Tetrachlorodibenzo-p-dioxin: Species differences in subunit dissociation

1990 • 33 citations

Kinetic models for association of 2,3,7,8-tetrachlorodibenzo-p-dioxin with the Ah receptor

1988 • 33 citations

Multiple DNA-binding Estrogen Receptor Forms Resolved by Interaction with Immobilized Metal Ions

1989 • 31 citations

Binding characteristics of 4‐S proteins from rat and mouse liver High affinity of ellipticines

1988 • 27 citations

Effect of zinc(II) and other divalent cations on binding of 3,5,3′-triiodo-L-thyronine to nuclear receptors from cultured GC cells

1989 • 21 citations

Metal binding sites of the estradiol receptor from calf uterus and their possible role in the regulation of receptor function

1989 • 21 citations

Protamine sulfate precipitation: A new assay for the Ah receptor

1984 • 18 citations