Identification of the Ah receptor in selected mammalian species and induction of aryl hydrocarbon hydroxylase

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

A Method for Determining the Sedimentation Behavior of Enzymes: Application to Protein Mixtures

1961 • 5,561 citations

Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.

1976 • 1,343 citations

Chemical Carcinogenesis

1975 • 741 citations

The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains, and developmental and hormonal states

1969 • 425 citations

Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation.

1979 • 401 citations

Genetic Mechanisms Controlling the Induction of Polysubstrate Monooxygenase (P-450) Activities

1981 • 296 citations

Binding of polychlorinated biphenyls classified as either phenobarbitone-, 3-methylcholanthrene- or mixed-type inducers to cytosolic Ah receptor

1982 • 258 citations

Separation of the hormone- and DNA-binding sites of the hepatic glucocorticoid receptor by means of proteolysis.

1978 • 258 citations

Microsomes, drug oxidations, and drug toxicity

1982 • 187 citations

The Ah locus: Correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA

1982 • 184 citations

Nuclear uptake of 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6J and DBA/2J mice. Role of the hepatic cytosol receptor protein.

1979 • 173 citations

The examination and quantitation of tissue cytosolic receptors for 2,3,7,8-tetrachlorodibenzo-p-dioxin using hydroxylapatite

1982 • 168 citations

Metabolism of benzo[a]pyrene

1975 • 148 citations

Kinetic analysis of the metabolism of benzo(a)pyrene to phenols, dihydrodiols, and quinones by high-pressure chromatography compared to analysis by aryl hydrocarbon hydroxylase assay, and the effect of enzyme induction.

1975 • 124 citations

Tissue distribution of the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat.

1979 • 122 citations

Molecular Mechanisms of Steroid Hormone Action

1978 • 117 citations

Structure-activity relationships in halogenated biphenyls: Unifying hypothesis for structural specificity

1981 • 109 citations

Characteristics and differences in the hepatic mixed function oxidase of different species

1979 • 107 citations

Graphical Methods in Enzyme Chemistry

1957 • 106 citations

Cytosolic and Nuclear Binding of 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin to the AhReceptor in Extra‐Hepatic Tissues of Rats and Mice

1982 • 103 citations

Structural gene product of the [Ah] complex. Evidence for transcriptional control of cytochrome P1-450 induction by use of a cloned DNA sequence.

1981 • 93 citations

Binding of 3-Methylcholanthrene and 2,3,7,8-Tetrachlorodibenzo-p-dioxin to a Common Ah Receptor Site in Mouse and Rat Hepatic Cytosols

1982 • 90 citations

Species differences in the substrate specificity of hepatic cytochrome P-448 From polycyclic hydrocarbon-treated animals

1979 • 85 citations

Formation and characterisitcs of hepatic dexamethasone-receptor complexes of different molecular weight

1977 • 84 citations

Ontogenetic Expression of Regulatory and Structural Gene Products Associated with the Ah Locus

1980 • 70 citations

The Ah Receptor: Controlling Factor in the Induction of Drug-Metabolizing Enzymes by Certain Chemical Carcinogens and Other Environmental Pollutants

1983 • 69 citations

Effect of Ionic Strength on Charcoal Adsorption Assays of Receptor-Estradiol Complexes

1977 • 55 citations

A direct fluorometric assay of benzo[a]pyrene hydroxylase

1978 • 53 citations

Interaction of the hepatic receptor protein for 2,3,7,8-tetrachlorodibenzo-p-dioxin with DNA

1981 • 48 citations

Quantitation of hepatic cytochrome P1-450 mRNA with the use of a cloned DNA probe. Effects of various P-450 inducers in C57BL/6N and DBA/2N mice.

1982 • 37 citations

The relationship between polarizability of polychlorinated biphenyls and their induction of mixed function oxidase activity

1981 • 32 citations

High-affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin in cell nuclei from rat liver

1982 • 31 citations

Cell Genetics of Glucocorticoid Responsiveness

1980 • 25 citations

STRUCTURAL SPECIFICITY AND THE DIOXIN RECEPTOR

1982 • 23 citations

Microsomal Aryl Hydrocarbon Hydroxylase Comparison of the Direct, Indirect and Radiometric Assays

1983 • 23 citations

Quantitation of endogenously occupied and unoccupied binding sites for 1,25-dihydroxyvitamin D3 in rat intestine.

1983 • 22 citations

Subcellular events occurring during aryl hydrocarbon hydroxylase induction: no requirement for metabolism of polycyclic hydrocarbon inducer.

1977 • 18 citations

Interaction of steroids with some pyrimidine and purine derivatives

1962 • 16 citations

Apparent absence of requirement of hydrocarbon metabolism for induction and repression of mixed-function oxidases

1980 • 9 citations