Kinetic considerations for the regulation of adenosine and deoxyadenosine metabolism in mouse and human tissues based on a thymocyte model

Identification and quantitation of adenine deoxynucleotides in erythrocytes of a patient with adenosine deaminase deficiency and severe combined immunodeficiency.

1978 • 277 citations

Apparent suicide inactivation of human lymphoblast S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine and adenine arabinoside. A basis for direct toxic effects of analogs of adenosine.

1979 • 277 citations

Overproduction of adenine deoxynucleosides and deoxynucletides in adenosine deaminase deficiency with severe combined immunodeficiency disease.

1978 • 200 citations

Adenosine kinase from rabbit liver. II. Substrate and inhibitor specificity

1979 • 178 citations

Uptake and metabolism of adenosine by human erythrocyte ghosts

1972 • 173 citations

In vivo inactivation of erythrocyte S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine in adenosine deaminase-deficient patients.

1979 • 168 citations

Human adenosine deaminase. Purification and subunit structure.

1977 • 154 citations

Adenosine metabolism in phytohemagglutinin-stimulated human lymphocytes.

1976 • 149 citations

A study of the tissue distribution of adenosine deaminase in six mammal species

1965 • 144 citations

ADENOSINE-DEAMINASE DEFICIENCY AND COMBINED IMMUNODEFICIENCY SYNDROME

1972 • 133 citations

Human placental adenosine kinase. Kinetic mechanism and inhibition.

1980 • 111 citations

Adenosine metabolism in human erythrocytes

1971 • 106 citations

Alternative Pathways of Deoxyadenosine and Adenosine Metabolism

1973 • 99 citations

Partial purification and properties of the common inherited forms of adenosine deaminase from human erythrocytes

1973 • 99 citations

Differences in deoxyadenosine metabolism in human and mouse lymphocytes.

1980 • 71 citations

Toxicity of naturally occuring purine deoxyribonucleosides

1980 • 71 citations

Inhibition of animal and invertebrate cell growth by naturally occurring purine bases and ribonucleosides

1980 • 52 citations

Adenosine metabolism in human erythrocytes: A study of some factors which affect the metabolic fate of adenosine in intact red cells in vitro

1980 • 25 citations

A comparison of purine metabolism and nucleotide pools in normal and hypoxanthine-guanine phosphoribosyltransferase-deficient neuroblastoma cells

1978 • 24 citations

Purine ribonucleoside and deoxyribonucleoside kinase activities in thymocytes. Specificity and optimal assay conditions for phosphorylation

1980 • 23 citations

2-Deoxycoformycin inhibition of intracellular phosphorylation of adenosine in Novikoff rat hepatoma cells

1981 • 15 citations

Elucidation of aberrant purine metabolism. Application to hypoxanthine-guanine phosphoribosyltransferase- and adenosine kinase-deficient mutants, and IMP dehydrogenase- and adenosine deaminase-inhibited human lymphoblasts

1980 • 7 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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