Endocardial endothelium mediates positive inotropic response to alpha1-adrenoceptor agonist in mammalian heart

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

The cellular basis of the length-tension relation in cardiac muscle

1985 • 581 citations

Membrane-cytoskeleton interaction

1983 • 389 citations

Actions of sympathomimetic amines on the Ca2+ transients and contractions of rabbit myocardium: reciprocal changes in myofibrillar responsiveness to Ca2+ mediated through alpha- and beta-adrenoceptors.

1988 • 337 citations

Actin Filament Stress Fibers in Vascular Endothelial Cells in Vivo

1983 • 334 citations

Alpha 1-adrenergic and muscarinic cholinergic stimulation of phosphoinositide hydrolysis in adult rat cardiomyocytes.

1985 • 298 citations

Calcium‐ and length‐dependent force production in rat ventricular muscle

1982 • 297 citations

Increased alpha-adrenergic receptors in ischemic cat myocardium. A potential mediator of electrophysiological derangements.

1981 • 263 citations

Effects of damaging the endocardial surface on the mechanical performance of isolated cardiac muscle.

1988 • 260 citations

Alpha 1-adrenoceptor-mediated phosphoinositide breakdown and inotropic response in rat left ventricular papillary muscles.

1988 • 210 citations

Endothelium-Removal Decreases Relaxations of Canine Coronary Arteries Caused by β-Adrenergic Agonists and Adenosine

1985 • 194 citations

Modification of myofibrillar responsiveness to Ca++ as an inotropic mechanism.

1986 • 184 citations

Demonstration of contractile protein in endothelium and cells of the heart valves, endocardium, intima, arteriosclerotic plaques, and Aschoff bodies of rheumatic heart disease.

1969 • 159 citations

Inotropic drugs and their mechanisms of action

1984 • 151 citations

On the presence and distribution of ?-adrenoceptors in the heart of various mammalian species

1978 • 151 citations

Effects of noradrenaline and isoprenaline, in combination with α‐ and β‐receptor blocking substances, on the action potential of cardiac Purkinje fibres

1973 • 136 citations

Positive inotropic effects of phenylephrine in the isolated rabbit papillary muscle mediated both by ?-and ?-adrenoceptors

1974 • 135 citations

Inositol phosphate production following α₁‐adrenergic, muscarinic or electrical stimulation in isolated rat heart

1986 • 129 citations

Effects of adrenergic amines on electrophysiological properties and automaticity of neonatal and adult canine Purkinje fibers: evidence for alpha- and beta-adrenergic actions.

1977 • 128 citations

Effects of α‐adrenoceptor stimulation with phenylephrine in the presence of propranolol on force of contraction, slow inward current and cyclic AMP content in the bovine heart

1984 • 125 citations

Existence and functional role of alpha1-adrenoceptors in the mammalian heart

1985 • 121 citations

α-adrenoceptor-mediated positive inotropic effect of phenylephrine in isolated human ventricular myocardium

1984 • 115 citations

Alpha-1 adrenoceptor-mediated positive inotropic effect and inositol trisphosphate increase in mammalian heart.

1988 • 110 citations

Effects of selective alpha 1‐, alpha 2‐, beta 1‐and beta 2‐adrenoceptor stimulation on potentials and contractions in the rabbit heart.

1984 • 100 citations

Calcium Measurements in Serum and Plasma—Total and Ionized

1979 • 97 citations

INTESTINAL CAPILLARIES

1969 • 85 citations

Electrophysiologic and Antiarrhythmic Effects of Phentolamine in Experimental Coronary Artery Occlusion and Reperfusion in the Dog

1980 • 81 citations

Long-chain acylcarnitines mediate the hypoxia-induced increase in alpha 1-adrenergic receptors on adult canine myocytes.

1987 • 81 citations

Atriopeptin III induces early relaxation of isolated mammalian papillary muscle.

1988 • 81 citations

Anti‐arrhythmic effects of prazosin and propranolol during coronary artery occlusion and re‐perfusion in dogs and pigs

1984 • 80 citations

Positive inotropic effects of methoxamine: evidence for alpha-adrenergic receptors in ventricular myocardium

1975 • 77 citations

Functional and subcellular changes in the isolated rat heart perfused with oxidized isoproterenol

1978 • 71 citations

Electrophysiologic effects of epinephrine in humans

1988 • 70 citations

Are there α-adrenoceptors in the mammalian heart?

1979 • 66 citations

Evidence for α1-Adrenoceptor-Mediated Increase of Inositol Trisphosphate in the Human Heart

1989 • 63 citations

A novel effect of norepinephrine on cardiac cells is mediated by alpha 1-adrenoceptors

1989 • 55 citations

Effects of α- and β-adrenergic agonists, phosphodiesterase inhibitors and adenosine on isolated human heart muscle preparations

1987 • 53 citations

Pertussis toxin does not inhibit the α1-adrenoceptor-mediated effect on inositol phosphate production in the heart

1987 • 53 citations

Potentiometric determination of serum ionized calcium in a normal human population

1972 • 51 citations

Effects of phenylephrine on calcium current and contractility of feline ventricular myocytes

1988 • 51 citations

Alpha-adrenergic receptors on rat ventricular myocytes: characteristics and linkage to cAMP metabolism

1986 • 48 citations

Alpha1 adrenoceptors in the ischaemic and reperfused myocardium

1988 • 45 citations

The regional and species differences on the activation of myocardial alpha-adrenoceptors by phenylephrine and methoxamine

1980 • 44 citations

Phorbol ester does not mimic, but antagonizes the alpha-adrenoceptor-mediated positive inotropic effect in the rabbit papillary muscle

1988 • 44 citations

Alpha-adrenergic receptor stimulation during simulated ischemia and reperfusion in canine cardiac Purkinje fibers.

1988 • 37 citations

Facilitated determination of ionized calcium.

1985 • 34 citations

Noradrenaline Evokes an α‐Adrenoceptor‐mediated Inotropic Effect in Human Ventricular Myocardium

1986 • 33 citations

α-adrenergic regulation of action potentials in isolated rat cardiomyocytes

1989 • 30 citations

Effects of α-adrenoceptor stimulation on electrophysiological properties and mechanics in rat papillary muscle

1987 • 30 citations

Comparison of muscarinic and α-adrenergic receptors in rat atria based on phosphoinositide turnover

1984 • 28 citations

Effect of ?- and ?-sympathomimetic agonists on calcium-dependent slow action potential and force of contraction in the rabbit papillary muscle

1982 • 27 citations

Ca2+ depletion-induced disconnection of tight junctions in isolated rat brain microvessels

1985 • 23 citations

Alpha adrenoceptors—An overview

1986 • 22 citations

Alpha adrenoceptors and arrhythmias

1986 • 21 citations

Cardiac α-adrenoceptors: postjunctional and prejunctional

1986 • 18 citations

Characterization of the atrial α-receptor of the rat as a subgroup of the postsynaptic α-adrenoceptor

1980 • 14 citations

Alpha-adrenergic stimulation of 32PO4 labelling of phosphatidylinositol (PI) and phosphatidic acid (PA) in cultured rat heart cells

1982 • 8 citations

Endocardial control of myocardial performance.

1988 • 7 citations

Effects of Phenylephrine on Bovine Corneal Endothelium in Culture

1980 • 4 citations