Effects of selective alpha 1‐, alpha 2‐, beta 1‐and beta 2‐adrenoceptor stimulation on potentials and contractions in the rabbit heart.

Differentiation of Receptor Systems activated by Sympathomimetic Amines

1967 • 2,054 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

Presynaptic regulation of the release of catecholamines.

1980 • 1,483 citations

Presynaptic regulation of catecholamine release

1974 • 1,145 citations

The effect of the cardiac membrane potential on the rapid availability of the sodium‐carrying system

1955 • 763 citations

How does adrenaline accelerate the heart?

1979 • 563 citations

The Pharmacology of a β2-Selective Adrenoceptor Antagonist (ICI 118,551)

1983 • 419 citations

Alpha adrenergic contributions to dysrhythmia during myocardial ischemia and reperfusion in cats.

1980 • 377 citations

Inward current activated during hyperpolarization in the rabbit sinoatrial node cell

1980 • 297 citations

Increased alpha-adrenergic receptors in ischemic cat myocardium. A potential mediator of electrophysiological derangements.

1981 • 263 citations

Adrenaline: Mechanism of Action on the Pacemaker Potential in Cardiac Purkinje Fibers

1968 • 213 citations

Myocardial alpha adrenergic receptors and their role in the production of a positive inotropic effect by sympathomimetic agents.

1968 • 146 citations

Cardiac Purkinje fibres

1977 • 145 citations

The ionic basis of concentration‐related effects of noradrenaline on the action potential of calf cardiac purkinje fibres.

1982 • 144 citations

Effects of noradrenaline and isoprenaline, in combination with α‐ and β‐receptor blocking substances, on the action potential of cardiac Purkinje fibres

1973 • 136 citations

Effects of adrenergic amines on electrophysiological properties and automaticity of neonatal and adult canine Purkinje fibers: evidence for alpha- and beta-adrenergic actions.

1977 • 128 citations

β‐Adrenoceptors of the human myocardium: determination of β₁ and β₂ subtypes by radioligand binding

1983 • 102 citations

A study designed to explore the hypothesis that beta-1 adrenoceptors are "innervated" receptors and beta-2 adrenoceptors are "hormonal" receptors.

1981 • 99 citations

Alpha-adrenoceptor-mediated restoration of calcium-dependent potential in the partially depolarized rabbit papillary muscle

1978 • 86 citations

The dependence on heart rate of the human ventricular action potential duration

1982 • 85 citations

Pharmacological characterization of B-HT 933 (2-amino-6-ethyl-4,5,7,8-tetrahydro-6H-oxazolo-[5,4-d]-azepindihydrochloride) as a hypotensive agent of the ?Clonidine-type?

1977 • 83 citations

Electrophysiologic and Antiarrhythmic Effects of Phentolamine in Experimental Coronary Artery Occlusion and Reperfusion in the Dog

1980 • 81 citations

Myocardial alpha and beta adrenergic receptors as demonstrated by atrial functional refractory-period changes.

1966 • 81 citations

β-Adrenoceptor agonists increase membrane K+ conductance in cardiac Purkinje fibres

1983 • 75 citations

Coexistence of β1 and β2-Adrenoceptors in the Rabbit Heart

1982 • 73 citations

The effect of -adrenoceptor and Ca2+ antagonist drugs on the hypoxia-induced increase in resting tension

1978 • 69 citations

The effects of prolonged -adrenoceptor blockade on heart weight and cardiac intracellular potentials in rabbits

1975 • 65 citations

The effect of tetraethylammonium chloride on potassium permeability in the smooth muscle cell membrane of canine trachea.

1981 • 59 citations

Pirbuterol, a selecttve beta2 adrenergic bronchodilator.

1978 • 55 citations

Beta adrenoceptor interaction of full and partial agonists in the cat heart and soleus muscle.

1981 • 54 citations

The effect of selective α1- and α2-adrenoceptor stimulation on intraocular pressure in the conscious rabbit

1981 • 51 citations

Adaptation to prolonged beta-blockade of rabbit atrial, purkinje, and ventricular potentials, and of papillary muscle contraction. Time-course of development of and recovery from adaptation.

1981 • 50 citations

β2-Adrenoceptors in guinea-pig atria

1983 • 48 citations

Lack of correlation between the positive inotropic effect evoked by α-adrenoceptor stimulation and the levels of cyclic AMP and/or cyclic GMP in the isolated ventricle strip of the rabbit

1978 • 44 citations

The nature of the antagonism by methoxamine of the chronotropic and inotropic effects of catecholamines

1964 • 43 citations

Quantitative relations between cyclic AMP and contraction as affected by stimulators of adenylate cyclase and inhibitors of phosphodiesterase.

1975 • 41 citations

Adaptation of hypertensives to treatment with cardioselective and non-selective beta-blockers. Absence of correlation between bradycardia and blood pressure control, and reduction in slope of the QT/RR relation.

1980 • 40 citations

QT and action potential duration.

1982 • 36 citations

Response to Rimiterol and Salbutamol Aerosols Administered by Intermittent Positive-pressure Ventilation

1974 • 24 citations

ADAPTATIONAL RESPONSES TO PROLONGED β‐ADRENOCEPTOR BLOCKADE IN ADULT RABBITS

1980 • 19 citations

Beta-adrenolytic, antiarrhythmic and local anaesthetic effects of phenylephrine

1974 • 11 citations

Chronotropic responses of rabbit isolated atria to β-adrenoceptor agonists are mediated by only β1-adrenoceptors

1983 • 10 citations

The absence of effect of chemical sympathectomy on ventricular hypertrophy induced by hypoxia in young rabbits

1983 • 10 citations

Heart rate and QT interval in subjects adapted to beta-blockade: bradycardia and hypotension as uncorrelated adaptations

1983 • 5 citations