Total parenteral nutrition enriched with arginine and glutamate generates glutamine and limits protein catabolism in surgical patients hospitalized in intensive care units

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Clinical and Metabolic Efficacy of Glutamine-supplemented Parenteral Nutrition after Bone Marrow Transplantation

1992 • 763 citations

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1974 • 733 citations

The role of cellular hydration in the regulation of cell function

1996 • 571 citations

Nitrogen metabolism and ornithine cycle function

1990 • 556 citations

Arginine: Biochemistry, Physiology, and Therapeutic Implications

1986 • 526 citations

EFFECT OF PARENTERAL GLUTAMINE PEPTIDE SUPPLEMENTS ON MUSCLE GLUTAMINE LOSS AND NITROGEN BALANCE AFTER MAJOR SURGERY

1989 • 395 citations

A positive relationship between protein synthetic rate and intracellular glutamine concentration in perfused rat skeletal muscle

1987 • 285 citations

Immunonutrition: the role of arginine

1998 • 250 citations

Total Parenteral Nutrition With Glutamine Dipeptide After Major Abdominal Surgery

1998 • 235 citations

Amino acid determination in biological fluids by automated ion-exchange chromatography: performance of Hitachi L-8500A

1997 • 222 citations

Glutamine Metabolism and Its Physiologic Importance

1990 • 195 citations

Role of glutamine in immunologic responses

1998 • 192 citations

Arginine metabolism in mammals

1995 • 181 citations

Metabolic Response to Injury and Sepsis: Changes in Protein Metabolism

1997 • 150 citations

Metabolism of absorbed aspartate, asparagine, and arginine by rat small intestine in vivo

1976 • 150 citations

Alanyl-glutamine Counteracts the Depletion of Free Glutamine and the Postoperative Decline in Protein Synthesis in Skeletal Muscle

1990 • 119 citations

Assessment of an Automated Chemiluminescence Nitrogen Analyzer for Routine Use in Clinical Nutrition

1988 • 82 citations

Metabolism and function of polyamines

1985 • 75 citations

Old and New Substrates in Clinical Nutrition

1998 • 75 citations

The stability of L-glutamine in total parenteral nutrition solutions

1991 • 70 citations

Validity of 3-methylhistidine excretion as an indicator of skeletal muscle protein breakdown in humans

1988 • 68 citations

Amino acids with anabolic properties

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The Influence of Abdominal Surgical Trauma Upon the Turnover of Some Blood-Borne Energy Metabolites in the Human Leg

1981 • 51 citations

Glutamine and glutamate nitrogen exchangeable pools in cultured fibroblasts: A stable isotope study

1988 • 45 citations

Effect of parenteral l-glutamine on muscle in the very severely Ill

1996 • 45 citations

Factors affecting the stability of L-glutamine in solution

1991 • 40 citations

Metabolism of ornithine, α-ketoglutarate and arginine in isolated perfused rat liver

1995 • 36 citations

Effect of Parenteral ?-Glutamine on Muscle in the Very Severely I11

1996 • 36 citations

Essential and Conditionally-Essential Nutrients in Clinical Nutrition

1993 • 31 citations

Exchange of 3-methylhistidine in the splanchnic region in human infection

1989 • 24 citations

Alteration of Whole‐Body Protein Kinetics According to Severity of Surgical Trauma in Patients Receiving Total Parenteral Nutrition

1991 • 18 citations

Plasma amino acid concentration changes after total parenteral nutrition (TPN) interruption in critically ill and surgical neoplastic patients

1987 • 7 citations

Place du bilan d'azote en nutrition artificielle

1992 • 6 citations

Glutamine containing dipeptides: an overview

1993 • 3 citations