Glutamine Metabolism and Its Physiologic Importance

Nutrition Needs of Mammalian Cells in Tissue Culture

1955 • 1,562 citations

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.

1979 • 1,228 citations

THE FREE AMINO ACIDS OF HUMAN BLOOD PLASMA

1954 • 939 citations

Intracellular free amino acid concentration in human muscle tissue.

1974 • 733 citations

Glutamine Utilization by the Small Intestine

1982 • 495 citations

THE NUTRITIVE SIGNIFICANCE OF THE AMINO ACIDS

1938 • 464 citations

GLUTAMINE METABOLISM IN LYMPHOCYTES: ITS BIOCHEMICAL, PHYSIOLOGICAL AND CLINICAL IMPORTANCE

1985 • 455 citations

Muscle and Plasma Amino Acids Following Injury Influence of Intercurrent Infection

1980 • 401 citations

The rate of gluconeogenesis from various precursors in the perfused rat liver

1967 • 397 citations

EFFECT OF PARENTERAL GLUTAMINE PEPTIDE SUPPLEMENTS ON MUSCLE GLUTAMINE LOSS AND NITROGEN BALANCE AFTER MAJOR SURGERY

1989 • 395 citations

Addition of Glutamine to Total Parenteral Nutrition After Elective Abdominal Surgery Spares Free Glutamine in Muscle, Counteracts the Fall in Muscle Protein Synthesis, and Improves Nitrogen Balance

1989 • 389 citations

The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells

1985 • 350 citations

THE GROWTH RESPONSE OF MAMMALIAN CELLS IN TISSUE CULTURE TO l-GLUTAMINE AND l-GLUTAMIC ACID

1956 • 349 citations

Metabolic disorders in severe abdominal sepsis: Glutamine deficiency in skeletal muscle

1982 • 332 citations

Effect of a Glutamine‐Supplemented Enteral Diet on Methotrexate‐Induced Enterocolitis

1988 • 321 citations

Glycolysis, glutaminolysis and cell proliferation

1982 • 305 citations

Maintenance of Small Bowel Mucosa with Glutamine‐Enriched Parenteral Nutrition

1989 • 286 citations

A positive relationship between protein synthetic rate and intracellular glutamine concentration in perfused rat skeletal muscle

1987 • 285 citations

Muscle and splanchnic glutamine and glutamate metabolism in postabsorptive and starved man

1971 • 280 citations

Reciprocal regulation of glucose and glutamine utilization by cultured human diploid fibroblasts

1978 • 274 citations

Amino Acid Metabolism and Its Disorders.

1974 • 255 citations

CHARACTERISTICS OF A GLUTAMINE CARRIER IN SKELETAL MUSCLE HAVE IMPORTANT CONSEQUENCES FOR NITROGEN LOSS IN INJURY, INFECTION, AND CHRONIC DISEASE

1986 • 206 citations

Relationship between glutamine concentration and protein synthesis in rat skeletal muscle

1988 • 206 citations

Metabolism of Glutamine

1956 • 155 citations

Renal production and excretion of ammonia

1964 • 154 citations

Energy metabolism in respiration‐deficient and wild type chinese hamster fibroblasts in culture

1976 • 152 citations

Stimulation of hepatic glycogen synthesis by amino acids.

1976 • 144 citations

23. Glutamine Synthetase of Mammals

1974 • 142 citations

Glutaminase activities and growth rates of rat hepatomas.

1969 • 112 citations

The proportionality of glutaminase content to growth rate and morphology of rat neoplasms.

1969 • 112 citations

Effects of glucocorticoids on glutamine metabolism in visceral organs

1985 • 96 citations

THE ROLE OF GLUTAMINE IN PROTEIN BIOSYNTHESIS IN TISSUE CULTURE

1957 • 91 citations

Catalytic Mechanism of Glutamine Synthetase; Overview of Glutamine Metabolism

1980 • 72 citations

Special Lecture: Glutamine Metabolism in the Animal Body

1980 • 55 citations

The isolation of glutamine from an enzymic digest of gliadin

1932 • 40 citations

Branched Chain Amino Acid Uptake and Muscle Free Amino Acid Concentrations Predict Postoperative Muscle Nitrogen Balance

1986 • 38 citations

Imbalance of purine metabolism in hepatomas of different growth rates as expressed in behavior of glutamine-phosphoribosylpyrophosphate amidotransferase (amidophosphoribosyltransferase, EC 2.4.2.14).

1975 • 37 citations

The effect of glucose on glutamine utilization by Ehrlich ascites tumor cells.

1961 • 30 citations

Ueber die Proteïnstoffe

1873 • 28 citations