Tumor Necrosis Factor Alone Does Not Explain the Lethal Effect of Lipopolysaccharide

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Tumor Necrosis Factor (TNF)

1985 • 1,932 citations

Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration

1988 • 1,711 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Galactosamine-induced sensitization to the lethal effects of endotoxin.

1979 • 940 citations

Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo.

1985 • 788 citations

Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits.

1988 • 603 citations

Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock.

1989 • 567 citations

Evidence that tumor necrosis factor has an important role in antibacterial resistance.

1989 • 422 citations

TOLERANCE TO BACTERIAL PYROGENS

1947 • 334 citations

Growth inhibition of Candida albicans by human polymorphonuclear neutrophils: activation by interferon-gamma and tumor necrosis factor.

1986 • 293 citations

Synergy between tumor necrosis factor and bacterial products causes hemorrhagic necrosis and lethal shock in normal mice.

1988 • 260 citations

Inhibition of murine malaria (Plasmodium chabaudi) in vivo by recombinant interferon-gamma or tumor necrosis factor, and its enhancement by butylated hydroxyanisole.

1987 • 219 citations

Clinical pharmacology of recombinant human tumor necrosis factor in patients with advanced cancer.

1987 • 216 citations

Gamma Interferon Priming of Mouse and Human Macrophages for Induction of Tumor Necrosis Factor Production by Bacterial Lipopolysaccharide

1987 • 212 citations

Production and clearance of tumor necrosis factor in rats exposed to endotoxin and dexamethasone

1987 • 196 citations

Pretreatment with recombinant murine tumor necrosis factor alpha/cachectin and murine interleukin 1 alpha protects mice from lethal bacterial infection.

1989 • 196 citations

Endotoxin Tolerance Is Associated With Reduced Secretion of Tumor Necrosis Factor

1989 • 127 citations

Corynebacterium parvum as the Priming Agent in the Production of Tumor Necrosis Factor in the Mouse2

1977 • 124 citations

Mechanisms of endotoxin tolerance. V. Specificity of the early and late phases of pyrogenic tolerance.

1969 • 118 citations

Induction of tumor necrosis factor, IFN-gamma, and acute lethality in mice by toxic and non-toxic forms of lipid A.

1988 • 109 citations

Regulation of serum tumor necrosis factor in glucocorticoid-sensitive and -resistant rodent endotoxin shock models

1989 • 61 citations

MECHANISMS OF ENDOTOXIN TOLERANCE

1965 • 59 citations

Pharmacokinetics of Murine Tumor Necrosis Factor

1986 • 53 citations

Protection of mice against Listeria monocytogenes infection by recombinant human tumor necrosis factor alpha

1989 • 50 citations

Tumor Necrosis Factor and Interleukin 1 as Mediators of Endotoxin-Induced Beneficial Effects

1987 • 42 citations

Production of tumor necrosis factor in unprimed mice: Mechanism of endotoxin-mediated tumor necrosis

1986 • 39 citations

Evaluation of the mechanism of zymosan-induced resistance to experimental peritonitis.

1978 • 32 citations

Failure of tumor necrosis factor to produce hypotensive shock in the absence of endotoxin.

1989 • 29 citations

Salmonellosis in Mice Infected with Mycobacterium tuberculosis BCG I. Role of Endotoxin in Infection

1968 • 20 citations

Endotoxin lethality and tolerance in mice: analysis with the B-lymphocyte-defective CBA/N strain

1979 • 17 citations

Total hypothermic blood exchange in acute endotoxin shock

1979 • 4 citations