Normative melatonin excretion: a multinational study

Applied logistic regression

1990 • 37,000 citations

Light Suppresses Melatonin Secretion in Humans

1980 • 1,873 citations

Melatonin in Humans

1997 • 1,521 citations

The Pineal Gland: A Neurochemical Transducer

1974 • 872 citations

A review of the evidence supporting melatonin's role as an antioxidant

1995 • 827 citations

Melatonin: A Coordinating Signal for Mammalian Reproduction?

1985 • 631 citations

Effect of inducing nocturnal serum melatoninconcentrations in daytime on sleep, mood, body temperature, andperformance.

1994 • 577 citations

Enzymatic O-Methylation of N-Acetylserotonin to Melatonin

1960 • 427 citations

Human Melatonin Production Decreases With Age

1986 • 411 citations

Role of the pineal gland in immunity

1986 • 409 citations

Age-Dependent Reduction in Serum Melatonin Concentrations in Healthy Human Subjects

1982 • 379 citations

Immunoassay of 6-Hydroxymelatonin Sulfate in Human Plasma and Urine: Abolition of the Urinary 24-Hour Rhythm with Atenolol*

1985 • 346 citations

The Fate of Melatonin in Animals

1961 • 341 citations

Melatonin and sleep in humans

1993 • 324 citations

A chronobiological study of melatonin and cortisol secretion in depressed subjects: plasma melatonin, a biochemical marker in major depression.

1984 • 295 citations

Control of Circadian Change of Serotonin N -Acetyltransferase Activity in the Pineal Organ by the β-Adrenergic Receptor

1972 • 290 citations

Daily Rhythm in Human Urinary Melatonin

1975 • 262 citations

Melatonin Metabolism: Neural Regulation of Pineal Serotonin: Acetyl Coenzyme A N -Acetyltransferase Activity

1971 • 261 citations

Circadian rhythms of melatonin and cortisol in aging

1989 • 249 citations

Differences in nocturnal melatonin secretion between melancholic depressed patients and control subjects

1985 • 247 citations

Melatonin in relation to body measures, sex, age, season and the use of drugs in patients with major affective disorders and healthy subjects

1984 • 233 citations

Daily variation in the concentration of melatonin and 5-methoxytryptophol in the human pineal gland: effect of age and Alzheimer's disease

1990 • 218 citations

AGE-ASSOCIATED REDUCTION IN NOCTURNAL PINEAL MELATONIN LEVELS IN FEMALE RATS1

1981 • 215 citations

Role of the pineal gland in immunity: II. Melatonin enhances the antibody response via an opiatergic mechanism.

1987 • 213 citations

Melatonin in humans physiological and clinical studies.

1978 • 203 citations

Pineal gland interface between the photoperiodic environment and the endocrine system

1991 • 190 citations

HUMAN SERUM MELATONIN CHANGES DURING THE MENSTRUAL CYCLE

1976 • 181 citations

Psychiatric Disorder, Hospital Admission, and Season

1978 • 161 citations

T‐Helper‐2 lymphocytes as a peripheral target of melatonin*

1995 • 157 citations

Static and extremely low frequency electromagnetic field exposure: Reported effects on the circadian production of melatonin

1993 • 157 citations

Pharmacokinetics of Melatonin in Man: First Pass Hepatic Metabolism

1985 • 156 citations

Light and Biological Rhythms in Man

1993 • 155 citations

The pineal gland and cancer

1988 • 155 citations

Melatonin Serum Levels and Metabolic Clearance Rate in Patients with Liver Cirrhosis

1982 • 151 citations

Immunomodulatory role of melatonin: specific binding sites in human and rodent lymphoid cells

1995 • 145 citations

Pineal Melatonin, Its Fundamental Immunoregulatory Role in Aging and Cancer

1988 • 144 citations

Melatonin and psychiatry

1988 • 142 citations

Melatonin, cortisol and ACTH in patients with major depressive disorder and healthy humans with special reference to the outcome of the dexamethasone suppression test

1985 • 139 citations

The Metabolism of Melatonin (N-Acetyl-5-methoxytryptamine) and 5-Methoxytryptamine

1961 • 136 citations

Plasma melatonin—An index of brain aging in humans?

1986 • 136 citations

The Circadian Pattern of Melatonin and Its Positive Relationship with Progesterone in Women

1986 • 136 citations

A Comparison of Melatonin Secretion in Depressed Patients and Normal Subjects

1988 • 135 citations

Seasonality in biochemical determinations: A source of variance and a clue to the temporal incidence of affective illness

1979 • 134 citations

Visual Pathway Mediating Pineal Response to Environmental Light

1967 • 133 citations

Circadian rhythm of plasma melatonin in endogenous depression

1984 • 133 citations

Urinary melatonin rhythms during sleep deprivation in depressed patients and normals

1977 • 132 citations

Minireview The influence of season, photoperiod, and pineal melatonin on immune function

1995 • 131 citations

A simplified radioimmunoassay for melatonin and its application to biological fluids. Preliminary observations on the half-life of plasma melatonin in man

1978 • 131 citations

Synchronization of mammalian circadian rhythms by melatonin.

1986 • 127 citations

REDUCED NOCTURNAL MELATONIN SECRETION IN CHRONIC SCHIZOPHRENIA: RELATIONSHIP TO BODY WEIGHT

1982 • 120 citations

Perspectives on season of suicide: A review

1980 • 103 citations

Long-Term Studies on Immunoreactive Human Melatonin

1979 • 97 citations

Melatonin in seasonal affective disorder and phototherapy.

1986 • 93 citations

Effects of acute tryptophan depletion on nocturnal melatonin secretion in humans.

1993 • 91 citations

24‐HOUR PROFILES OF MELATONIN, CORTISOL, INSULIN, C‐PEPTIDE AND GIP FOLLOWING A MEAL AND SUBSEQUENT FASTING

1982 • 87 citations

Melatonin modulates growth factor activity in MCF‐7 human breast cancer cells

1994 • 84 citations

The correlation between human plasma melatonin levels and urinary 6-hydroxymelatonin excretion

1985 • 73 citations

Evidence for Modulation of Melatonin Secretion in Men With Benign and Malignant Tumors of the Prostate: Relationship With the Pituitary Hormones

1985 • 72 citations

Fluctuation of Blood Melatonin Concentrations With Age: Result of Changes in Pineal Melatonin Secretion, Body Growth, and Aging

1990 • 69 citations

The Effect of Total Sleep Deprivation on Plasma Melatonin and Cortisol in Healthy Human Volunteers

1988 • 68 citations

Low and high melatonin excretors among healthy individuals

1995 • 68 citations

Physiological regulation of melatonin receptors in rat suprachiasmatic nuclei: diurnal rhythmicity and effects of stress

1993 • 67 citations

Alterations of the circadian melatonin rhythm by the electromagnetic spectrum: A study in environmental toxicology

1992 • 67 citations

Age- and sex-associated modification of plasma melatonin concentrations in man. Relationship to pathology, malignant or not, and autopsy findings

1985 • 66 citations

Propranolol in Schizophrenia

1980 • 60 citations

Melatonin as a Proconvulsive Hormone in Humans

1992 • 60 citations

Elevated daytime melatonin concentrations in autism: A pilot study

1993 • 60 citations

Age, alcoholism and depression are associated with low levels of urinary melatonin.

1992 • 57 citations

Melatonin in serum and urine in patients with idiopathic pain syndromes

1987 • 53 citations

Peptides and Exercise at High and Low Altitudes

1992 • 51 citations

Genetic regulation of melatonin excretion in urine

1983 • 50 citations

Temporal relationship between melatonin and cortisol responses to nighttime physical stress in humans

1992 • 48 citations

The 24 hour pattern of plasma melatonin in depressed patients before and after treatment.

1980 • 42 citations

Plasma Melatonin Concentrations in Depression

1986 • 40 citations

Measurement of Urinary Production Rates of Melatonin as an Index of Human Pineal Function

1980 • 39 citations

Acute treatment with desipramine stimulates melatonin and 6‐sulphatoxy melatonin production in man.

1986 • 36 citations

Effects of 6-methoxy-2-benzoxazolinone on the pineal melatonin generating system.

1985 • 26 citations

Plasma melatonin levels in depressed patients before and after treatment with antidepressant medication

1989 • 26 citations

Melatonin and Affective Disorders

1985 • 26 citations

Timekeeping in genetically programmed aging

1993 • 21 citations

Eeproducibility of the overnight melatonin secretion pattern in healthy men

1984 • 21 citations

Melatonin, Thymic Serum Factor, and Cortisol Levels in Healthy Subjects of Different Age and Patients With Skin Melanoma

1986 • 19 citations

The Pineal Gland and the Clinical Course of Multiple Sclerosis

1991 • 16 citations

The psychopharmacology of the human pineal

1987 • 16 citations

The Influence of Age, Sex, Height, Weight, Urine Volume and Latitude on Melatonin Concentrations in Urine from Normal Subjects: A Multinational Study

1993 • 15 citations

Monoamines, Depression and Antidepressant Drugs

1988 • 12 citations

Melatonin and steroid-dependent carcinomas.

1989 • 8 citations

Melatonin and Steroid-Dependent Carcinomas/Melatonin und Steroid-abhängige Carcinome

2009 • 6 citations

Deleted Work

1955 • 0 citations