Age, alcoholism and depression are associated with low levels of urinary melatonin.

Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat

1972 • 2,054 citations

The development, topographical relations and innervation of the epiphysis cerebri in the albino rat

1960 • 566 citations

A chronobiological study of melatonin and cortisol secretion in depressed subjects: plasma melatonin, a biochemical marker in major depression.

1984 • 295 citations

Differences in nocturnal melatonin secretion between melancholic depressed patients and control subjects

1985 • 247 citations

Melatonin in relation to body measures, sex, age, season and the use of drugs in patients with major affective disorders and healthy subjects

1984 • 233 citations

Melatonin in humans physiological and clinical studies.

1978 • 203 citations

Melatonin and psychiatry

1988 • 142 citations

Plasma melatonin—An index of brain aging in humans?

1986 • 136 citations

A Comparison of Melatonin Secretion in Depressed Patients and Normal Subjects

1988 • 135 citations

Visual Pathway Mediating Pineal Response to Environmental Light

1967 • 133 citations

Circadian rhythm of plasma melatonin in endogenous depression

1984 • 133 citations

Urinary melatonin rhythms during sleep deprivation in depressed patients and normals

1977 • 132 citations

A simplified radioimmunoassay for melatonin and its application to biological fluids. Preliminary observations on the half-life of plasma melatonin in man

1978 • 131 citations

REDUCED NOCTURNAL MELATONIN SECRETION IN CHRONIC SCHIZOPHRENIA: RELATIONSHIP TO BODY WEIGHT

1982 • 120 citations

Monitoring the Effect of a Tryptophan Load on Brain Indole Metabolism in Freely Moving Rats by Simultaneous Cerebrospinal Fluid Sampling and Brain Dialysis

1985 • 120 citations

The relationship between the pineal gland and the pituitary-adrenal axis in health, endocrine and psychiatric conditions

1983 • 109 citations

24‐HOUR PROFILES OF MELATONIN, CORTISOL, INSULIN, C‐PEPTIDE AND GIP FOLLOWING A MEAL AND SUBSEQUENT FASTING

1982 • 87 citations

Clinical Importance of Melatonin

1979 • 73 citations

Melatonin in serum and urine in patients with idiopathic pain syndromes

1987 • 53 citations

Effects of Steroids on Serotonin‐N‐Acetyltransferase Activity of Pineals in Organ Culture

1989 • 47 citations

The 24 hour pattern of plasma melatonin in depressed patients before and after treatment.

1980 • 42 citations

Plasma Melatonin Concentrations in Depression

1986 • 40 citations

Pineal function during ethanol intoxication, dependence, and withdrawal

1986 • 35 citations

Plasma melatonin levels in depressed patients before and after treatment with antidepressant medication

1989 • 26 citations

Urine melatonin in alcoholic patients: a marker of alcohol abuse?

1991 • 25 citations

Age-associated changes and sex differences in urinary 6-sulphatoxymelatonin circadian rhythm in the rat

1992 • 9 citations

Effects of acute ethanol administration on nocturnal pineal serotonin N-acetyltransferase activity

1988 • 8 citations