BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Genomic Aberrations and Survival in Chronic Lymphocytic Leukemia

2000 • 3,282 citations

Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection

2000 • 3,126 citations

Unmutated Ig VH Genes Are Associated With a More Aggressive Form of Chronic Lymphocytic Leukemia

1999 • 2,674 citations

Signalling pathways of the TNF superfamily: a double-edged sword

2003 • 2,602 citations

Ig V Gene Mutation Status and CD38 Expression As Novel Prognostic Indicators in Chronic Lymphocytic Leukemia

1999 • 2,557 citations

Features of apoptotic cells measured by flow cytometry

1992 • 1,912 citations

Chronic Lymphocytic Leukemia

2005 • 1,679 citations

Failure to Regulate TNF-Induced NF-κB and Cell Death Responses in A20-Deficient Mice

2000 • 1,374 citations

ZAP-70 Expression as a Surrogate for Immunoglobulin-Variable-Region Mutations in Chronic Lymphocytic Leukemia

2003 • 1,366 citations

Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia

2001 • 1,110 citations

Gene Expression Profiling of B Cell Chronic Lymphocytic Leukemia Reveals a Homogeneous Phenotype Related to Memory B Cells

2001 • 934 citations

ZAP-70 Compared with Immunoglobulin Heavy-Chain Gene Mutation Status as a Predictor of Disease Progression in Chronic Lymphocytic Leukemia

2004 • 933 citations

Chronic Lymphocytic Leukemia

1995 • 799 citations

All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction

2002 • 594 citations

Early Growth Response Protein 1 (Egr-1): Prototype of a Zinc-finger Family of Transcription Factors

1995 • 593 citations

In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

2005 • 579 citations

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1.

1995 • 548 citations

Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia

2002 • 530 citations

Human c- myc Transcription Factor PuF Identified as nm23-H2 Nucleoside Diphosphate Kinase, a Candidate Suppressor of Tumor Metastasis

1993 • 504 citations

Multiple Distinct Sets of Stereotyped Antigen Receptors Indicate a Role for Antigen in Promoting Chronic Lymphocytic Leukemia

2004 • 433 citations

B-Cell Chronic Lymphocytic Leukemia: A Bird of a Different Feather

1999 • 408 citations

NFATc1 and NFATc2 Together Control Both T and B Cell Activation and Differentiation

2001 • 397 citations

Direct Regulation of ZAP-70 by SHP-1 in T Cell Antigen Receptor Signaling

1996 • 390 citations

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

2007 • 311 citations

ZAP-70 directly enhances IgM signaling in chronic lymphocytic leukemia

2004 • 254 citations

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis

2005 • 234 citations

Reversible anergy of sIgM-mediated signaling in the two subsets of CLL defined by VH-gene mutational status

2007 • 226 citations

Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy

2008 • 224 citations

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis

2005 • 219 citations

CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells

2003 • 194 citations

CD38 expression distinguishes two groups of B-cell chronic lymphocytic leukemias with different responses to anti-IgM antibodies and propensity to apoptosis

1996 • 192 citations

ZAP-70 enhances B-cell–receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells

2006 • 178 citations

CD38 and ZAP-70 are functionally linked and mark CLL cells with high migratory potential

2007 • 168 citations

CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells

2007 • 161 citations

Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex.

1994 • 148 citations

Dynamics of Oxidation of a Fe ²⁺ -Bearing Aluminosilicate (Basaltic) Melt

1996 • 148 citations

Gene expression profiling of follicular lymphoma and normal germinal center B cells using cDNA arrays

2002 • 146 citations

The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease

2006 • 142 citations

Roles of Chemokines and Receptor Polarization in NK-Target Cell Interactions

1998 • 102 citations

Survival Response to B-Cell Receptor Ligation Is Restricted to Progressive Chronic Lymphocytic Leukemia Cells Irrespective of Zap70 Expression

2006 • 97 citations

Apoptosis or plasma cell differentiation of CD38-positive B-chronic lymphocytic leukemia cells induced by cross-linking of surface IgM or IgD

2000 • 91 citations

Chronic lymphocytic leukemia patients with highly stable and indolent disease show distinctive phenotypic and genotypic features

2003 • 89 citations

Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemia

2003 • 86 citations

Regulation of the Human Chemokine Receptor CCR1

2000 • 73 citations

Regulation and Function of Cyclin D2 in B Lymphocyte Subsets

2004 • 67 citations

Several Dual Specificity Phosphatases Coordinate to Control the Magnitude and Duration of JNK Activation in Signaling Response to Oxidative Stress

2007 • 59 citations

The prognostic value of CD38 expression in chronic lymphocytic leukaemia patients studied prospectively at diagnosis: a single institute experience

2005 • 57 citations

Temporal genetic program following B-cell receptor cross-linking: altered balance between proliferation and death in healthy and malignant B cells

2007 • 51 citations

CDC25B Phosphorylation by p38 and MK-2

2006 • 50 citations

The B-cell receptor and ZAP-70 in chronic lymphocytic leukemia

2007 • 42 citations

Reduced susceptibility to apoptosis correlates with kinetic quiescence in disease progression of chronic lymphocytic leukaemia

2001 • 32 citations

New developments in the diagnosis, prognosis and treatment of chronic lymphocytic leukemia

2005 • 27 citations

Gene expression profile and genomic changes in disease progression of early-stage chronic lymphocytic leukemia

2007 • 24 citations

Novel roles of NM23 proteins in skin homeostasis, repair and disease

2006 • 21 citations