Antinociceptive effects of acute and ‘chronic’ injections of tricyclic antidepressant drugs in a new model of mononeuropathy in rats

Ethical guidelines for investigations of experimental pain in conscious animals

1983 • 7,639 citations

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

1988 • 5,129 citations

Studies of the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine

1971 • 1,433 citations

Amitriptyline relieves diabetic neuropathy pain in patients with normal or depressed mood

1987 • 695 citations

Citalopram — Pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity

1982 • 589 citations

Amitriptyline versus placebo in postherpetic neuralgia

1982 • 563 citations

Further evidence for ‘pain-related’ behaviours in a model of unilateral peripheral mononeuropathy

1990 • 504 citations

Amitriptyline, but not lorazepam, relieves postherpetic neuralgia

1988 • 411 citations

Efficacy of desipramine in painful diabetic neuropathy: a placebo-controlled trial

1991 • 302 citations

Desipramine relieves postherpetic neuralgia

1990 • 270 citations

Endogenous pain control mechanisms

1979 • 179 citations

Local and remote modifications of nociceptive sensitivity during carrageenin-induced inflammation in the rat

1987 • 179 citations

Interaction of tricyclic antidepressants with opiate receptors

1980 • 139 citations

Concentration-response relationship in imipramine treatment of diabetic neuropathy symptoms

1990 • 131 citations

Depression Masquerading as Diabetic Neuropathy

1981 • 129 citations

Antidepressant analgesia in rheumatoid arthritis.

1988 • 107 citations

Reduction of arthritis and pain behaviour following chronic administration of amitriptyline or imipramine in rats with adjuvant-induced arthritis

1985 • 88 citations

Influence of naloxone and methysergide on the analgesic effect of clomipramine in rats

1981 • 88 citations

An Open and Double-Blind Cross-Over Study on the Efficacy of Clomipramine (Anafranil®) in Patients with Painful Mono- and Polyneuropathies

1982 • 82 citations

Analgesic properties of intrathecally administered heterocyclic antidepressants

1987 • 77 citations

Test-specific effects of the 5-HT reuptake inhibitors alaproclate and zimelidine on pain sensitivity and morphine analgesia

1980 • 74 citations

Autotomy behavior in rats following peripheral deafferentation is suppressed by daily injections of amitriptyline, diazepam and saline

1989 • 70 citations

Drug disposition during development

1978 • 67 citations

Hypoalgesia induced by antidepressants in mice: A case for opioids and serotonin

1986 • 65 citations

Pharmacological modulation of edema mediated by prostaglandin, serotonin and histamine

1980 • 61 citations

Low dose amitriptyline in chronic pain: The gain is modest

1990 • 55 citations

Behavioural evidence for a bidirectional effect of systemic naloxone in a model of experimental neuropathy in the rat

1989 • 53 citations

Influence of naloxone on the antinociceptive effects of some antidepressant drugs.

1985 • 50 citations

The ‘tonic’ pain-related behaviour seen in mononeuropathic rats is modulated by morphine and naloxone

1991 • 46 citations

Contribution to the Pharmacokinetics of Amitriptyline

1978 • 43 citations

Clinical Response and Tricyclic Plasma Levels During Treatment with Clomipramine

1979 • 40 citations

Pharmacokinetic patterns of repeated administration of antidepressants in animals. I. Implications for antinociceptive action of clomipramine in mice.

1988 • 40 citations

Depression masquerading as diabetic neuropathy

1980 • 40 citations

Do acute or chronic tricyclic antidepressants modify morphine antinociception in arthritic rats?

1986 • 40 citations

Pharmacology of descending control systems

1985 • 38 citations

Dissociation of the mechanisms of stimulation-produced analgesia (SPA) in tests of tonic and phasic pain

1981 • 37 citations

Pharmacokinetics of amitriptyline infused intravenously in man

1976 • 35 citations

Evidence for a central but not a peripheral analgesic effect of clomipramine in rats

1991 • 34 citations

Chronic amitriptyline decreases autotomy following dorsal rhizotomy in rats

1989 • 33 citations

Modification of the antinociceptive effect of morphine by acute and chronic administration of clomipramine in mice

1988 • 31 citations

The apparent antinociceptive effect of desipramine and zimelidine in the tail flick test in rats is mainly caused by changes in tail skin temperature

1989 • 31 citations

Antinociceptive effects of serotonergic reuptake inhibitors in mice

1989 • 30 citations

Selected Tricyclic Antidepressants in the Management of Chronic Benign Pain*

1988 • 27 citations

Acute and chronic treatment with selective serotonin uptake inhibitors in mice: effects on nociceptive sensitivity and response to 5-methoxy- N, N -dimethyltryptamine

1988 • 19 citations

Chronic Treatment with Antidepressant Drugs and the Analgesia Induced by 5‐Methoxy‐N,N‐dimethyltryptamine: Attenuation by Desipramine

1986 • 19 citations

Anti-nociceptive effect of tricyclic anti-depressants following intrathecal administration.

1984 • 11 citations

Measurement of the fractional ratio of demethylation of imipramine in rat by using a co-administration technique.

1988 • 3 citations