Hypoalgesia induced by antidepressants in mice: A case for opioids and serotonin

Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin Circuitry

1984 • 2,580 citations

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

1980 • 840 citations

On the specificity of naloxone as an opiate antagonist

1979 • 611 citations

Blockade by antidepressants and related compounds of biogenic amine uptake into rat brain synaptosomes: Most antidepressants selectively block norepinephrine uptake

1984 • 528 citations

Serotonin-containing neurons: their possible role in pain and analgesia

1977 • 394 citations

Serotonin neurons in nucleus raphe dorsalis and paragigantocellularis of the cat contain enkephalin.

1981 • 180 citations

Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes

1984 • 168 citations

Increase in potencies of opioid peptides after peptidase inhibition

1983 • 143 citations

Participation of both ‘enkephalinase’ and aminopeptidase activities in the metabolism of endogenous enkephalins

1983 • 140 citations

Interaction of tricyclic antidepressants with opiate receptors

1980 • 139 citations

Lumbar intrathecal naloxone blocks analgesia produced by microstimulation of the ventromedial medulla in the rat

1982 • 130 citations

Comparison between naloxone reversal of morphine and electrical stimulation induced analgesia in the rat mesencephalon

1976 • 105 citations

Influence of naloxone and methysergide on the analgesic effect of clomipramine in rats

1981 • 88 citations

Possible involvement of opiate receptors in the pharmacological profiles of antidepressant compounds

1984 • 80 citations

Naloxone Antagonism as Evidence for Narcotic Mechanisms

1977 • 79 citations

PAIN

1982 • 69 citations

Chronic antidepressant treatment increases enkephalin levels in n. Accumbens and striatum of the rat

1985 • 66 citations

Potentiation of morphine analgesia by cocaine in mice

1968 • 64 citations

Antidepressants and opiates interactions: Pharmacological and biochemical evidences

1983 • 60 citations

Comparative study of the effects of mianserin, a tetracyclic antidepressant, and of imipramine on uptake and release of neurotransmitters in synaptosomes

1976 • 56 citations

Tricyclic antidepressants in treatment of depression and chronic pain: analysis of the supporting evidence.

1984 • 48 citations

Distribution of Alkaline Phosphatase Variants in a Heteroploid Strain of Human Cells in Tissue Culture

1962 • 45 citations

Tricyclic Antidepressants in Treatment of Depression and Chronic Pain

1984 • 41 citations

Increased sensitivity of the central nervous system to morphine analgesia by amitriptyline in naive and morphine-tolerant rats

1981 • 40 citations

Pharmacokinetics of naloxone and naltrexone in the dog.

1979 • 39 citations

Increase in rat cortical [3H]naloxone binding site density after chronic administration of antidepressant agents

1984 • 33 citations

Antidepressants Inhibit Enkephalin Binding to Synaptosome-Enriched Fractions of Rat Brain

1981 • 22 citations