Anticonvulsant activity of the NMDA antagonists, d(−)4-(3-phosphonopropyl)piperazine-2-carboxylic acid (D-CPP) and d(−)(E)-4-(3-phosphonoprop-2-enyl) piperazine-2-carboxylic acid (D-CPPene) in a rodent and a primate model of reflex epilepsy

A simplified method of evaluating dose-effect experiments.

1948 • 7,047 citations

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

Anticonvulsant Action of Excitatory Amino Acid Antagonists

1982 • 692 citations

CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]d-AP5 binding sites on brain membranes and anticonvulsant activity

1986 • 311 citations

CPP, a selective N-methyl-D-aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo.

1987 • 231 citations

CGS 19755, a selective and competitive N-methyl-D-aspartate-type excitatory amino acid receptor antagonist.

1988 • 219 citations

Antiepileptic action of excitatory amino acid antagonists in the photosensitive baboon, papio papio

1983 • 179 citations

Synthesis and NMD A Antagonistic Properties of the Enantiomers of 4‐(3‐phosphonopropyl)piperazine‐2‐carboxylic acid (CPP) and of the unsaturated analogue (E)‐4‐(3‐phosphonoprop‐2‐enyl)piperazine‐2‐carboxylic acid (CPP‐ene)

1989 • 109 citations

Anticonvulsant action and biochemical effects in DBA/2 mice of CPP (3-((±)-2-carboxypiperazin-4-yl)-propyl-1-phosphonate), a novel N-methyl-D-aspartate antagonist

1987 • 54 citations

Potent oral anticonvulsant action of CPP and CPPene in DBA/2 mice

1990 • 41 citations

The Conformation of Cycloartenol Investigated by NMR and Molecular Mechanics

1989 • 38 citations

CGP 37849 and CGP 39551: novel competitive N-methyl-D-aspartate receptor antagonists with potent oral anticonvulsant activity.

1990 • 8 citations