CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]d-AP5 binding sites on brain membranes and anticonvulsant activity

Excitatory Amino Acid Transmitters

1981 • 2,488 citations

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

Possible Therapeutic Applications of Antagonists of Excitatory Amino acid Neurotransmitters

1985 • 558 citations

2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation

1981 • 468 citations

THE EFFECTS OF A SERIES OF ω‐PHOSPHONIC α‐CARBOXYLIC AMINO ACIDS ON ELECTRICALLY EVOKED AND EXCITANT AMINO ACID‐INDUCED RESPONSES IN ISOLATED SPINAL CORD PREPARATIONS

1982 • 463 citations

Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord

1982 • 302 citations

L-Glutamate has higher affinity than other amino acids for [3H]-D-AP5 binding sites in rat brain membranes

1984 • 293 citations

Receptors for the excitatory amino acids in the mammalian central nervous system

1983 • 292 citations

Role of excitatory amino acid receptors in mono- and polysynaptic excitation in the cat spinal cord

1983 • 243 citations

Action of 3-((±)-2-car☐ypiperazin-4-yl)-propyl-1-phosphonic aci (CPP): a new and highly potent antagonist of N-methyl-d-aspartate receptors in the hippocampus

1986 • 239 citations

ANTAGONISM OF EXCITATORY AMINO ACID‐INDUCED RESPONSES AND OF SYNAPTIC EXCITATION IN THE ISOLATED SPINAL CORD OF THE FROG

1979 • 152 citations

Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones

1981 • 132 citations

Muscle relaxant action of excitatory amino acid antagonists

1985 • 100 citations

Structure-activity relations of dipeptide antagonists of excitatory amino acids

1984 • 88 citations

Specific antagonism of excitant amino acids in the isolated spinal cord of the neonatal rat

1978 • 75 citations

Isomers of 2-amino-7-phosphonoheptanoic acid as antagonists of neuronal excitants

1982 • 60 citations

Amino acid receptor mediated excitatory synaptic transmission in the cat red nucleus.

1986 • 47 citations

Recent Advances in the Pharmacology of Excitatory Amino Acids in the Mammalian Central Nervous System

1983 • 25 citations