Synthesis and NMD A Antagonistic Properties of the Enantiomers of 4‐(3‐phosphonopropyl)piperazine‐2‐carboxylic acid (CPP) and of the unsaturated analogue (E)‐4‐(3‐phosphonoprop‐2‐enyl)piperazine‐2‐carboxylic acid (CPP‐ene)

Agonists and antagonists for excitatory amino acid receptors

1987 • 692 citations

CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]d-AP5 binding sites on brain membranes and anticonvulsant activity

1986 • 311 citations

The N-methyl-d-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils

1988 • 246 citations

Action of 3-((±)-2-car☐ypiperazin-4-yl)-propyl-1-phosphonic aci (CPP): a new and highly potent antagonist of N-methyl-d-aspartate receptors in the hippocampus

1986 • 239 citations

CPP, a selective N-methyl-D-aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo.

1987 • 231 citations

Pharmacological analysis of drug-receptor interaction

1994 • 212 citations

Pharmacology of the corticocaudate excitatory postsynaptic potential in the cat: Evidence for its mediation by quisqualateor kainate-receptors

1985 • 201 citations

Muscle relaxant and anticonvulsant activity of 3-((±)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid, a novel antagonist, in rodents

1987 • 189 citations

Excitatory amino acid neurotransmission

1988 • 173 citations

In vitro release and electrophysiological effects in situ of homocysteic acid, an endogenous N-methyl-(D)-aspartic acid agonist, in the mammalian striatum

1986 • 135 citations

[3H]CPP, a new competitive ligand for NMDA receptors

1986 • 108 citations

A Facile Synthesis ofN ²-Protected L-2,3-Diaminopropanoic Acid

1981 • 102 citations

Distinct pharmacological properties of excitatory amino acid receptors in the rat striatum: study by Na+ efflux assay.

1981 • 91 citations

Excitatory amino acid receptor subtypes and specific antagonists

1989 • 76 citations

Studies on phosphonic acid antibiotics. IV. Synthesis and antibacterial activity of analogs of 3-(N-acetyl-N-hydroxyamino)-propylphosphonic acid (FR-900098).

1982 • 55 citations

Über C‐substituierte Piperazinderivate Untersuchungen über Synthetische Arzneimittel, 10. Mitteilung

1962 • 30 citations

Über die katalytische Hydrierung von Pyrazincarbonsäuren

1960 • 25 citations

Synthesis of actinomycin and analogs. 12. Synthesis and some properties and antitumor effects of the actinomycin lactam analog, [di-(1'-L-.alpha.,.beta.-diaminopropionic acid)]actinomycin D

1976 • 21 citations

Chapter 4 Excitatory Amino Acids and Mammalian CNS Function

1987 • 12 citations