New genes in the MHC that encode proteins for antigen processing

Sequence analysis of peptides bound to MHC class II molecules

1991 • 1,071 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

Empty MHC class I molecules come out in the cold

1990 • 933 citations

Identification of self peptides bound to purified HLA-B27

1991 • 844 citations

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

1990 • 717 citations

Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

1990 • 689 citations

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

1990 • 644 citations

The multicatalytic proteinase complex, a major extralysosomal proteolytic system

1990 • 464 citations

Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing

1990 • 438 citations

Cellular peptide composition governed by major histocompatibility complex class I molecules

1990 • 438 citations

Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid.

1986 • 437 citations

A proteasome-related gene between the two ABC transporter loci in the class II region of the human MHC

1991 • 427 citations

MHC class II region encoding proteins related to the muKidrug resistance family of transmembrane transporters

1990 • 426 citations

Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro

1990 • 418 citations

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

1991 • 413 citations

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

1991 • 394 citations

Presentation of viral antigen controlled by a gene in the major histocompatibility complex

1990 • 381 citations

Second proteasome-related gene in the human MHC class II region

1991 • 348 citations

Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter

1991 • 329 citations

Structural and serological similarity of MHC-linked LMP and proteasome (multicatalytic proteinase) complexes

1991 • 310 citations

A role for peptide in determining MHC class II structure

1991 • 275 citations

Binding protein-dependent transport systems

1990 • 272 citations

Subunit of the '20S' proteasome (multicatalytic proteinase) encoded by the major histocompatibility complex

1991 • 262 citations

Homology of proteasome subunits to a major histocompatibility complex-linked LMP gene

1991 • 256 citations

Peptide selection by MHC class I molecules

1991 • 253 citations

Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes

1990 • 236 citations

Endogenously synthesized peptide with an endoplasmic reticulum signal sequence sensitizes antigen processing mutant cells to class I-restricted cell-mediated lysis.

1991 • 215 citations

A recycling pathway between the endoplasmic reticulum and the Golgi apparatus for retention of unassembled MHC class I molecules

1991 • 188 citations

The binding affinity and dissociation rates of peptides for class I major histocompatibility complex molecules

1991 • 187 citations

ATP‐dependent reversible association of proteasomes with multiple protein components to form 26S complexes that degrade ubiquitinated proteins in human HL‐60 cells

1991 • 141 citations

Molecular analysis of H-2-deficient lymphoma lines. Distinct defects in biosynthesis and association of MHC class I heavy chains and beta 2-microglobulin observed in cells with increased sensitivity to NK cell lysis.

1989 • 115 citations

A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex.

1991 • 106 citations

Degradation of oxidized insulin B chain by the multiproteinase complex macropain (proteasome)

1991 • 99 citations

The LMP antigens: A stable MHC-controlled multisubunit protein complex

1986 • 93 citations

ATP is required for in vitro assembly of MHC class I antigens but not to transfer of peptides acrosss the ER membrane

1991 • 92 citations

How do peptides associate with MHC class I molecules?

1991 • 55 citations

Eukaryotic protein degradation

1990 • 30 citations

Mutations affecting antigen processing impair class II-restricted allorecognition.

1991 • 26 citations