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Sp1- and Krüppel-like transcription factors.

Data up to Jan 2025

Published2003
Citations902
References58

Total Citations Per Year

Abstract

References (58)

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The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

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Sp1 and krüppel‐like factor family of transcription factors in cell growth regulation and cancer

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Kruppel-Like Factor 15 Modulates Renal Interstitial Fibrosis by ERK/MAPK and JNK/MAPK Pathways Regulation

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2001 • 600 citations

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1992 • 577 citations

Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

1995 • 572 citations

Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression.

1992 • 533 citations

A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation.

1994 • 531 citations

Transcription Factor Sp1 Is Essential for Early Embryonic Development but Dispensable for Cell Growth and Differentiation

1997 • 524 citations

The biology of the mammalian Krüppel-like family of transcription factors

2000 • 444 citations

KLF6 , a Candidate Tumor Suppressor Gene Mutated in Prostate Cancer

2001 • 426 citations

Zif268 protein–DNA complex refined at 1.6å: a model system for understanding zinc finger–DNA interactions

1996 • 416 citations

Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene.

1992 • 354 citations

The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1

1999 • 350 citations

Mammalian Krüppel-like transcription factors: more than just a pretty finger

1999 • 296 citations

Sp3 Is a Bifunctional Transcription Regulator with Modular Independent Activation and Repression Domains

1997 • 284 citations

Ancient origin of the Hox gene cluster

2001 • 255 citations

The thyroid hormone-induced tail resorption program during Xenopus laevis metamorphosis.

1996 • 246 citations

Positive- and Negative-acting Krüppel-like Transcription Factors Bind a Transforming Growth Factor β Control Element Required for Expression of the Smooth Muscle Cell Differentiation Marker SM22α in Vivo

2000 • 244 citations

Increase of GKLF messenger RNA and protein expression during progression of breast cancer.

2000 • 236 citations

Molecular Cloning and Characterization of TIEG2Reveals a New Subfamily of Transforming Growth Factor-β-inducible Sp1-like Zinc Finger-encoding Genes Involved in the Regulation of Cell Growth

1998 • 190 citations

Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF.

1999 • 189 citations

Site-Specific Acetylation by p300 or CREB Binding Protein Regulates Erythroid Krüppel-Like Factor Transcriptional Activity via Its Interaction with the SWI-SNF Complex

2001 • 181 citations

A Conserved α-Helical Motif Mediates the Interaction of Sp1-Like Transcriptional Repressors with the Corepressor mSin3A

2001 • 181 citations

Growth/Cell Cycle Regulation of Sp1 Phosphorylation

1999 • 174 citations

A 2.2 Å resolution crystal structure of a designed zinc finger protein bound to DNA

1996 • 172 citations

A Drosophila homologue of human Sp1 is a head-specific segmentation gene

1993 • 166 citations

Human Kruppel-like Factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription

2000 • 160 citations

Sp1 and Its Likes: Biochemical and Functional Predictions for a Growing Family of Zinc Finger Transcription Factors

1999 • 146 citations

Structures of Zinc Finger Domains from Transcription Factor Sp1

1997 • 133 citations

Two Potent Nuclear Localization Signals in the Gut-enriched Krüppel-like Factor Define a Subfamily of Closely Related Krüppel Proteins

1997 • 131 citations

The Gut-enriched Krüppel-like Factor Suppresses the Activity of the CYP1A1 Promoter in an Sp1-dependent Fashion

1998 • 129 citations

Recognition of DNA by Cys 2 ,His 2 Zinc Fingers

1991 • 124 citations

Three Conserved Transcriptional Repressor Domains Are a Defining Feature of the TIEG Subfamily of Sp1-like Zinc Finger Proteins

1999 • 119 citations

Cloning of GT Box-Binding Proteins: A Novel Spl Multigene Family Regulating T-Cell Receptor Gene Expression

1992 • 114 citations

FKLF, a Novel Krüppel-Like Factor That Activates Human Embryonic and Fetal β-Like Globin Genes

1999 • 113 citations

The zebrafish klf gene family

2001 • 111 citations

RFLAT-1

1999 • 106 citations

FKLF-2: a novel Krüppel-like transcriptional factor that activates globin and other erythroid lineage genes

2000 • 84 citations

The Sp1-like Protein BTEB3 Inhibits Transcription via the Basic Transcription Element Box by Interacting with mSin3A and HDAC-1 Co-repressors and Competing with Sp1

2001 • 80 citations

Functional Interaction between Coactivators CBP/p300, PCAF, and Transcription Factor FKLF2

2002 • 76 citations

Complex β-Satellite Repeat Structures and the Expansion of the Zinc Finger Gene Cluster in 19p12

1998 • 68 citations

Basic Krüppel-like factor functions within a network of interacting haematopoietic transcription factors

1999 • 68 citations

Functional Domains and DNA-binding Sequences of RFLAT-1/KLF13, a Krüppel-like Transcription Factor of Activated T Lymphocytes

2002 • 57 citations

Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoter

2002 • 57 citations

Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor

2002 • 55 citations

Comparison of DNA-Binding Properties between BTEB and Sp11

1993 • 51 citations

Enhanced Sp1 DNA-binding activity in murine keratinocyte cell lines and epidermal tumors

1999 • 44 citations

Common and diverged functions of the Drosophila gene pair D-Sp1 and buttonhead

1999 • 40 citations

Mouse BTEB3, a new member of the basic transcription element binding protein (BTEB) family, activates expression from GC-rich minimal promoter regions

2000 • 39 citations

Analysis of Functional Domains of a GC Box-Binding Protein, BTEB1

1995 • 32 citations

Beyond the Hox complex.

2000 • 24 citations

XSPR-1 and XSPR-2, novel Sp1 related zinc finger containing genes, are dynamically expressed during Xenopus embryogenesis

2002 • 23 citations

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