Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: invitro phosphorylation of MCM subunits by a putative human homologue of Cdc7

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

1992 • 1,279 citations

Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products

1991 • 1,182 citations

Saccharomyces cerevisiae cell cycle

1974 • 747 citations

A Yeast Chromosomal Origin of DNA Replication Defined by Multiple Functional Elements

1992 • 634 citations

Expression cloning of the human IL-3 receptor cDNA reveals a shared β subunit for the human IL-3 and GM-CSF receptors

1991 • 617 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

Two steps in the assembly of complexes at yeast replication origins in vivo

1994 • 566 citations

Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition.

1984 • 545 citations

Yeast Origin Recognition Complex Functions in Transcription Silencing and DNA Replication

1993 • 435 citations

Protein-DNA interactions at a yeast replication origin

1992 • 380 citations

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

1996 • 362 citations

Purification of an MCM-containing complex as a component of the DNA replication licensing system

1995 • 361 citations

ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome

1995 • 357 citations

Origin Recognition Complex (ORC) in Transcriptional Silencing and DNA Replication in S. cerevisiae

1993 • 314 citations

Identification of the yeast MCM3-related protein as a component of xenopus DNA replication licensing factor

1995 • 280 citations

Cell Cycle Regulation of the Yeast Cdc7 Protein Kinase by Association With the Dbf4 Protein†

1993 • 250 citations

Conserved Initiator Proteins in Eukaryotes

1995 • 246 citations

BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication.

1995 • 234 citations

Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.

1993 • 233 citations

Interaction of Dbf4, the Cdc7 Protein Kinase Regulatory Subunit, with Yeast Replication Origins in Vivo

1994 • 213 citations

Role for a Xenopus Orc2-related protein in controlling DNA replication

1996 • 207 citations

The origin recognition complex interacts with a bipartite DNA binding site within yeast replicators.

1995 • 204 citations

The origin recognition complex in silencing, cell cycle progression, and DNA replication.

1995 • 204 citations

Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor

1993 • 198 citations

The origin recognition complex has essential functions in transcriptional silencing and chromosomal replication.

1995 • 187 citations

Initiation complex assembly at budding yeast replication origins begins with the recognition of a bipartite sequence by limiting amounts of the initiator, ORC.

1995 • 179 citations

DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period.

1994 • 173 citations

REGULATION OF EUKARYOTIC DNA REPLICATION

1994 • 170 citations

hsk1+, a Schizosaccharomyces pombe gene related to Saccharomyces cerevisiae CDC7, is required for chromosomal replication.

1995 • 152 citations

A Drosophila Homolog of the Yeast Origin Recognition Complex

1995 • 152 citations

Functional conservation of multiple elements in yeast chromosomal replicators.

1994 • 145 citations

Properties of the nuclear P1 protein, a mammalian homologue of the yeast Mcm3 replication protein

1992 • 137 citations

Interaction of Cdc2 and CdclS with a fission yeast ORC2-like protein

1996 • 131 citations

Molecular characterization of cell cycle gene CDC7 from Saccharomyces cerevisiae.

1986 • 126 citations

Domain B of ARS307 contains two functional elements and contributes to chromosomal replication origin function.

1994 • 123 citations

Chromatin binding, nuclear localization and phosphorylation of Xenopus cdc21 are cell-cycle dependent and associated with the control of initiation of DNA replication.

1996 • 112 citations

Temperature-sensitive cdc7 mutations of Saccharomyces cerevisiae are suppressed by the DBF4 gene, which is required for the G1/S cell cycle transition.

1992 • 103 citations

The P1 family: a new class of nuclear mammalian proteins related to the yeast Mem replication proteins

1993 • 87 citations

Cell proliferation and DNA replication defects in a Drosophila MCM2 mutant.

1995 • 82 citations

Differential regulation of the yeast CDC7 gene during mitosis and meiosis.

1988 • 74 citations

Regulation of Saccharomyces cerevisiae CDC7 function during the cell cycle.

1993 • 73 citations

Molecular cloning of cDNA encoding mouse Cdc21 and CDC46 homologs and characterization of the products: physical interaction between P1 (MCM3) and CDC46 proteins

1995 • 71 citations

Analysis of the interactions of functional domains of a nuclear origin of replication fromSaccharomyces cerevisiae

1991 • 65 citations

Recent developments in the initiation of chromosomal DNA replication: a complex picture emerges

1994 • 61 citations

On the nature of replication origins in higher eukaryotes

1995 • 58 citations

Separation of Origin Recognition Complex Functions by Cross-Species Complementation

1995 • 55 citations

Cdc7 protein kinase for DNA metabolism comes of age

1994 • 54 citations

Functional Conservation of Multiple Elements in Yeast Chromosomal Replicators

1994 • 54 citations

Eukaryotic replicators and associated protein complexes

1995 • 46 citations

Domain B of ARS307 Contains Two Functional Elements and Contributes to Chromosomal Replication Origin Function

1994 • 40 citations

Molecular Characterization of Cell Cycle Gene CDC7 from Saccharomyces cerevisiae

1986 • 35 citations

Replication origins in eukaroytes

1996 • 34 citations

Prokaryotic and eukaryotic replicons

1995 • 31 citations

Cell cycle control of eukaryotic DNA replication

1996 • 24 citations

Differential Regulation of the Yeast CDC7 Gene During Mitosis and Meiosis

1988 • 23 citations

CTBP1/RBP1, a Saccharomyces Cerevisiae Protein which Binds to T‐Rich Single‐Stranded DNA Containing the 11‐bp Core Sequence of Autonomously Replicating Sequence, is a Poly(Deoxypyrimidine)‐Binding Protein

1996 • 13 citations

A fusion protein library: an improved method for rapid screening and characterization of DNA binding or interacting proteins

1996 • 7 citations

Techniques for Monitoring Cell Cycle Phases

1996 • 4 citations