Adipogenesis: a cross-talk between cell proliferation and cell differentiation

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

1994 • 3,477 citations

Transcriptional regulation of adipogenesis

2000 • 1,875 citations

E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins

1992 • 1,552 citations

Adipogenesis and Obesity: Rounding Out the Big Picture

1996 • 1,268 citations

ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism.

1996 • 1,004 citations

Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins.

1995 • 922 citations

Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha.

1995 • 651 citations

Induction of Peroxisome Proliferator-Activated Receptor γ during the Conversion of 3T3 Fibroblasts into Adipocytes Is Mediated by C/EBPβ, C/EBPδ, and Glucocorticoids

1996 • 590 citations

ADD1: a Novel Helix-Loop-Helix Transcription Factor Associated with Adipocyte Determination and Differentiation

1993 • 575 citations

Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes.

1988 • 506 citations

Regulation of cell proliferation by the E2F transcription factors

1998 • 486 citations

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs.

1996 • 446 citations

Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F

1992 • 381 citations

PPARγ induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A

1997 • 379 citations

The growth of adipose tissue in children and adolescents. Cross-sectional and longitudinal studies of adipose cell number and size.

1979 • 374 citations

E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle.

1995 • 336 citations

E2F Repression by C/EBPα Is Required for Adipogenesis and Granulopoiesis In Vivo

2001 • 321 citations

E2Fs Regulate Adipocyte Differentiation

2002 • 310 citations

Role of PPARγ in Regulating a Cascade Expression of Cyclin-dependent Kinase Inhibitors, p18(INK4c) and p21(Waf1/Cip1), during Adipogenesis

1999 • 308 citations

Roles of Autocrine TGF-β Receptor and Smad Signaling in Adipocyte Differentiation

2000 • 303 citations

Transcriptional control of adipogenesis

1998 • 301 citations

Enforced expression of the c-myc oncogene inhibits cell differentiation by precluding entry into a distinct predifferentiation state in G0/G1.

1988 • 273 citations

Binding to DNA and the Retinoblastoma Gene Product Promoted by Complex Formation of Different E2F Family Members

1993 • 271 citations

The Retinoblastoma-Histone Deacetylase 3 Complex Inhibits PPARγ and Adipocyte Differentiation

2002 • 253 citations

Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells.

1995 • 220 citations

Relation between Age of Onset of Obesity and Size and Number of Adipose Cells

1972 • 213 citations

Opposite Effects of Androgens and Estrogens on Adipogenesis in Rat Preadipocytes: Evidence for Sex and Site-Related Specificities and Possible Involvement of Insulin-Like Growth Factor 1 Receptor and Peroxisome Proliferator-Activated Receptorγ 21

2000 • 207 citations

Peroxisome Proliferator-activated Receptor γ Ligands Inhibit Retinoblastoma Phosphorylation and G1 → S Transition in Vascular Smooth Muscle Cells

2000 • 198 citations

Mitotic Clonal Expansion during Preadipocyte Differentiation: Calpain-mediated Turnover of p27

2000 • 185 citations

C/EBPα Inhibits Cell Growth via Direct Repression of E2F-DP-Mediated Transcription

2000 • 172 citations

Adipocyte macrophage colony-stimulating factor is a mediator of adipose tissue growth.

1998 • 146 citations

Opposing roles of pRB and p107 in adipocyte differentiation

2000 • 145 citations

DNA Synthesis and Mitotic Clonal Expansion Is Not a Required Step for 3T3-L1 Preadipocyte Differentiation into Adipocytes

2001 • 140 citations

Regulation and Expression of Retinoblastoma Proteins p107 and p130 during 3T3-L1 Adipocyte Differentiation

1997 • 136 citations

Requirement of fibroblast growth factor 10 in development of white adipose tissue

2002 • 133 citations

Analysis of cell cycle arrest in adipocyte differentiation

1999 • 126 citations

Adipose conversion of 3T3-L1 cells in a serum-free culture system depends on epidermal growth factor, insulin-like growth factor I, corticosterone, and cyclic AMP.

1990 • 123 citations

Analysis of p107-associated proteins: p107 associates with a form of E2F that differs from pRB-associated E2F-1

1993 • 113 citations

Transforming growth factor beta (TGF-beta) inhibits the differentiation of human adipocyte precursor cells in primary culture.

1994 • 88 citations

Growth Hormone and Adipocyte Function in Obesity

2000 • 80 citations

The mechanism of effect of growth hormone on preadipocyte and adipocyte function

2000 • 72 citations

Mitogenic and Antiadipogenic Properties of Human Growth Hormone in Differentiating Human Adipocyte Precursor Cells in Primary Culture1

1996 • 65 citations

Analysis of Myc/Max/Mad network members in adipogenesis: Inhibition of the proliferative burst and differentiation by ectopically expressed Mad1

2000 • 61 citations

The block of adipocyte differentiation by a C-terminally truncated, but not by full-length, simian virus 40 large tumor antigen is dependent on an intact retinoblastoma susceptibility protein family binding domain

1996 • 39 citations

E2Fs and the Retinoblastoma Protein Family

1997 • 31 citations

Inhibition of the Terminal Stages of Adipocyte Differentiation by cMyc

2000 • 30 citations

Body Fat in GH-Deficient Children and the Effect of Treatment

1993 • 27 citations

Early expression of p107 is associated with 3T3-L1 adipocyte differentiation

2002 • 20 citations