Mitotic Clonal Expansion during Preadipocyte Differentiation: Calpain-mediated Turnover of p27

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Inhibitors of mammalian G1 cyclin-dependent kinases.

1995 • 3,258 citations

G1 phase progression: Cycling on cue

1994 • 2,706 citations

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer.

1994 • 2,176 citations

Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27

1995 • 1,848 citations

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

1995 • 1,601 citations

Mice Lacking p27 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors

1996 • 1,583 citations

E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins

1992 • 1,552 citations

A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 -Deficient Mice

1996 • 1,488 citations

Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27

1996 • 1,283 citations

TRANSCRIPTIONAL REGULATION OF GENE EXPRESSION DURING ADIPOCYTE DIFFERENTIATION

1995 • 1,033 citations

Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins.

1995 • 922 citations

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

1992 • 906 citations

Transcriptional regulation

1991 • 893 citations

CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

1991 • 733 citations

Calpain: new perspectives in molecular diversity and physiological‐pathological involvement

1994 • 673 citations

Regulation of Adipocyte Development

1994 • 631 citations

Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes.

1980 • 593 citations

Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes.

1989 • 587 citations

Differential activation of adipogenesis by multiple PPAR isoforms.

1996 • 470 citations

CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program.

1994 • 433 citations

Lactacystin, Proteasome Function, and Cell Fate

1998 • 420 citations

CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein.

1996 • 393 citations

Control of pRB phosphorylation

1998 • 389 citations

PPARγ induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A

1997 • 379 citations

Induction of lipogenesis during differentiation in a "preadipocyte" cell line.

1976 • 317 citations

Cyclins, Cyclin-Dependent Kinases and Cdk Inhibitors: Implications in Cell Cycle Control and Cancer

1995 • 314 citations

Reciprocal Regulation of Adipogenesis by Myc and C/EBPα

1992 • 296 citations

Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes.

1985 • 292 citations

The restriction point and control of cell proliferation

1997 • 253 citations

ADIPOCYTE DIFFERENTIATION AND LEPTIN EXPRESSION

1997 • 245 citations

Down-regulation of p27 by Two Mechanisms, Ubiquitin-mediated Degradation and Proteolytic Processing

1999 • 231 citations

Coupling of growth arrest and differentiation at a distinct state in the G1 phase of the cell cycle: GD.

1982 • 197 citations

Regulation of Cyclin D1 by Calpain Protease

1997 • 159 citations

Insulin Regulates Transcription of the CCAAT/Enhancer Binding Protein (C/EBP) α , β , and δ Genes in Fully-differentiated 3T3-L1 Adipocytes

1995 • 157 citations

Role of calpain in adipocyte differentiation

1999 • 104 citations

A closer look at E2F

1992 • 95 citations

Regulation of cyclin-dependent kinase 4 during adipogenesis involves switching of cyclin D subunits and concurrent binding of p18INK4c and p27Kip1.

1998 • 64 citations

Requirement for the Expression of Poly(ADP-ribose) Polymerase during the Early Stages of Differentiation of 3T3-L1 Preadipocytes, as Studied by Antisense RNA Induction

1995 • 60 citations

Evidence for Participation of a Calpain-like Cysteine Protease in Cell Cycle Progression through Late G1Phase

1997 • 46 citations

29 CCAAT/Enhancer Binding Protein

1992 • 13 citations