Antidepressants reverse the attenuation of the neurotrophic MEK/MAPK cascade in frontal cortex by elevated platform stress; reversal of effects on LTP is associated with GluA1 phosphorylation

Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene

2003 • 8,039 citations

Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain

2007 • 4,139 citations

Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human

1999 • 2,692 citations

Trk Receptors: Roles in Neuronal Signal Transduction

2003 • 2,410 citations

Causal Relationship Between Stressful Life Events and the Onset of Major Depression

1999 • 2,365 citations

A Molecular and Cellular Theory of Depression

1997 • 2,091 citations

THE EFFECTS OF STRESSFUL LIFE EVENTS ON DEPRESSION

1997 • 2,031 citations

Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus

1995 • 1,429 citations

NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

2007 • 1,089 citations

Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity

2000 • 1,085 citations

Molecular Psychology: Roles for the ERK MAP Kinase Cascade in Memory

2002 • 596 citations

The Prefrontal Cortex as a Key Target of the Maladaptive Response to Stress

2007 • 564 citations

Stress, depression, and anhedonia: Caveats concerning animal models

2005 • 549 citations

The Role of the Extracellular Signal-Regulated Kinase Signaling Pathway in Mood Modulation

2003 • 481 citations

Reversible Inhibition of CREB/ATF Transcription Factors in Region CA1 of the Dorsal Hippocampus Disrupts Hippocampus-Dependent Spatial Memory

2002 • 468 citations

Is it time to reassess the BDNF hypothesis of depression?

2007 • 393 citations

A Role for MAP Kinase Signaling in Behavioral Models of Depression and Antidepressant Treatment

2006 • 330 citations

Acute Stress-induced Changes in Hippocampal/Prefrontal Circuits in Rats: Effects of Antidepressants

2003 • 303 citations

Prolonged behavioral stress enhances synaptic connectivity in the basolateral amygdala

2006 • 292 citations

Involvement of AMPA receptor phosphorylation in antidepressant actions with special reference to tianeptine

2007 • 282 citations

Stress models of depression: Forming genetically vulnerable strains

2005 • 264 citations

How can drug discovery for psychiatric disorders be improved?

2007 • 236 citations

A role for AMPA receptors in mood disorders

2006 • 226 citations

Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D ₁ , dopamine D ₂ , and adenosine A _2A receptors

2000 • 193 citations

Immunohistochemical Evidence of Seizure-Induced Activation of trk Receptors in the Mossy Fiber Pathway of Adult Rat Hippocampus

1999 • 189 citations

The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats

2002 • 181 citations

Behavioral Stress Modifies Hippocampal Synaptic Plasticity through Corticosterone-Induced Sustained Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase Activation

2004 • 164 citations

Activation of Erk and JNK MAPK pathways by acute swim stress in rat brain regions.

2004 • 157 citations

Plasticity at hippocampal to prefrontal cortex synapses is impaired by loss of dopamine and stress: Importance for psychiatric diseases

2004 • 139 citations

BDNF increases rat brain mitochondrial respiratory coupling at complex I, but not complex II

2004 • 134 citations

Region-specific effects of acute and repeated restraint stress on the phosphorylation of mitogen-activated protein kinases

2003 • 103 citations

Differential effects of predator stress and the antidepressant tianeptine on physiological plasticity in the hippocampus and basolateral amygdala

2006 • 94 citations

Reduced basal CAMKII levels in hippocampal CA1 region: Possible cause of stress‐induced impairment of LTP in chronically stressed rats

2004 • 94 citations

Immunohistochemical Evidence of Seizure-Induced Activation of trkB Receptors in the Mossy Fiber Pathway of Adult Mouse Hippocampus

2002 • 79 citations

CaMKIIα enhances the desensitization of NR2B-containing NMDA receptors by an autophosphorylation-dependent mechanism

2005 • 75 citations

A pathophysiological paradigm for the therapy of psychiatric disease

2005 • 73 citations

Influence of immobilization stress on the levels of CaMKII and phospho-CaMKII in the rat hippocampus

2004 • 57 citations

Protection of stress-induced impairment of hippocampal/prefrontal LTP through blockade of glucocorticoid receptors

2008 • 48 citations

Stress induces the expression of heterotrimeric G protein β subunits and the phosphorylation of PKB/Akt and ERK1/2 in rat brain

2006 • 22 citations