Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

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2003 • 7,902 citations

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

2003 • 7,470 citations

Real-time quantification of microRNAs by stem-loop RT-PCR

2005 • 4,707 citations

NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

2006 • 4,019 citations

IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines

2005 • 3,466 citations

An essential role for Scurfin in CD4+CD25+ T regulatory cells

2003 • 2,825 citations

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

2005 • 2,667 citations

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

2005 • 2,256 citations

MicroRNA-155 is induced during the macrophage inflammatory response

2007 • 1,765 citations

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

2006 • 1,702 citations

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1996 • 1,648 citations

Regulation of the Germinal Center Response by MicroRNA-155

2007 • 1,476 citations

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

2008 • 1,438 citations

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

2009 • 1,274 citations

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2009 • 1,171 citations

miR-181a Is an Intrinsic Modulator of T Cell Sensitivity and Selection

2007 • 1,147 citations

Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling

2009 • 1,144 citations

Foxp3-dependent programme of regulatory T-cell differentiation

2007 • 1,106 citations

Pillars Article: Control of Regulatory T Cell Development by the Transcription Factor Foxp3. Science 2003. 299: 1057-1061.

2017 • 986 citations

CD4 ⁺ Regulatory T Cells Control T _H 17 Responses in a Stat3-Dependent Manner

2009 • 934 citations

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

2009 • 898 citations

Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3

2007 • 819 citations

Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells

2007 • 818 citations

Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma

2008 • 817 citations

Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases

2009 • 790 citations

SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine

1999 • 767 citations

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

2009 • 763 citations

MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2

2009 • 712 citations

MicroRNA‐146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

2009 • 710 citations

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

2007 • 695 citations

Suppressors of cytokine signaling and immunity

2003 • 607 citations

miR-24 Inhibits Cell Proliferation by Targeting E2F2, MYC, and Other Cell-Cycle Genes via Binding to “Seedless” 3′UTR MicroRNA Recognition Elements

2009 • 589 citations

Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection

2009 • 563 citations

The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs

2009 • 555 citations

SOCS1 Deficiency Causes a Lymphocyte-Dependent Perinatal Lethality

1999 • 531 citations

IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

2009 • 530 citations

An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

2006 • 523 citations

A role for Dicer in immune regulation

2006 • 514 citations

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

2008 • 510 citations

Regulatory T Cells in the Control of Host-Microorganism Interactions

2009 • 469 citations

Regulatory T cell development in the absence of functional Foxp3

2007 • 467 citations

MicroRNA profiling of the murine hematopoietic system.

2005 • 428 citations

Dicer-dependent microRNA pathway safeguards regulatory T cell function

2008 • 381 citations

Cutting Edge: The Foxp3 Target miR-155 Contributes to the Development of Regulatory T Cells

2009 • 372 citations

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease

2008 • 358 citations

Epstein-Barr Virus Latent Membrane Protein 1 Induces Cellular MicroRNA miR-146a, a Modulator of Lymphocyte Signaling Pathways

2007 • 301 citations

An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes

2009 • 289 citations

T-bet is required for optimal proinflammatory CD4+ T-cell trafficking

2005 • 260 citations

miR‐142‐3p restricts cAMP production in CD4⁺CD25⁻ T cells and CD4⁺CD25⁺ T_REG cells by targeting AC9 mRNA

2008 • 249 citations

Loss of Suppressor of Cytokine Signaling 1 in Helper T Cells Leads to Defective Th17 Differentiation by Enhancing Antagonistic Effects of IFN-γ on STAT3 and Smads

2008 • 181 citations

T-bet Binding to Newly Identified Target Gene Promoters Is Cell Type-independent but Results in Variable Context-dependent Functional Effects

2006 • 132 citations

Induction of the chemokine receptor CXCR3 on TCR-stimulated T cells: dependence on the release from persistent TCR-triggering and requirement for IFN-γ stimulation

2002 • 103 citations

Suppressor of cytokine signaling-1 ameliorates dextran sulfate sodium-induced colitis in mice

2008 • 86 citations

Molecular orchestration of differentiation and function of regulatory T cells

2009 • 77 citations

Differential Regulation of Foxp3 and IL-17 Expression in CD4 T Helper Cells by IRAK-1

2009 • 75 citations

A key pathogenic role for the STAT1/T-bet signaling pathway in T-cell-mediated liver inflammation

2003 • 63 citations

SOCS1 negatively regulates the production of Foxp3⁺ CD4⁺ T cells in the thymus

2009 • 27 citations

A key pathogenic role for the STAT1/T-bet signaling pathway in T-cell–mediated liver inflammation

2003 • 23 citations