Transcription and chromatin converge: lessons from yeast genetics

Genome-Wide Location and Function of DNA Binding Proteins

2000 • 1,720 citations

Acetylation of Histones and Transcription-Related Factors

2000 • 1,702 citations

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

1998 • 1,660 citations

Structure and ligand of a histone acetyltransferase bromodomain

1999 • 1,625 citations

Acetylation: a regulatory modification to rival phosphorylation?

2000 • 1,136 citations

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

1997 • 1,053 citations

Structure and Function of a Human TAF _II 250 Double Bromodomain Module

2000 • 808 citations

ATP-Dependent Chromatin-Remodeling Complexes

2000 • 734 citations

Ordered Recruitment of Chromatin Modifying and General Transcription Factors to the IFN-β Promoter

2000 • 716 citations

The TAFII250 Subunit of TFIID Has Histone Acetyltransferase Activity

1996 • 705 citations

Ordered Recruitment of Transcription and Chromatin Remodeling Factors to a Cell Cycle– and Developmentally Regulated Promoter

1999 • 703 citations

FACT, a Factor that Facilitates Transcript Elongation through Nucleosomes

1998 • 637 citations

The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins

1999 • 533 citations

Elongator, a Multisubunit Component of a Novel RNA Polymerase II Holoenzyme for Transcriptional Elongation

1999 • 482 citations

Global histone acetylation and deacetylation in yeast

2000 • 457 citations

A Novel Histone Acetyltransferase Is an Integral Subunit of Elongating RNA Polymerase II Holoenzyme

1999 • 453 citations

NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p

1999 • 452 citations

Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo

1998 • 444 citations

Promoter targeting and chromatin remodeling by the SWI/SNF complex

2000 • 433 citations

Histone deacetylases: silencers for hire

2000 • 429 citations

A Subset of TAFIIs Are Integral Components of the SAGA Complex Required for Nucleosome Acetylation and Transcriptional Stimulation

1998 • 419 citations

Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae

2000 • 398 citations

Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast

1999 • 389 citations

Characterization of the Imitation Switch subfamily of ATP-dependent chromatin-remodeling factors in Saccharomyces cerevisiae

1999 • 386 citations

Redundant roles for the TFIID and SAGA complexes in global transcription

2000 • 360 citations

Esa1p Is an Essential Histone Acetyltransferase Required for Cell Cycle Progression

1999 • 347 citations

Targeted Recruitment of the Sin3-Rpd3 Histone Deacetylase Complex Generates a Highly Localized Domain of Repressed Chromatin In Vivo

1998 • 319 citations

The Isw2 Chromatin Remodeling Complex Represses Early Meiotic Genes upon Recruitment by Ume6p

2000 • 307 citations

Requirement of RSF and FACT for Transcription of Chromatin Templates in Vitro

1998 • 298 citations

Coordinate Regulation of Yeast Ribosomal Protein Genes Is Associated with Targeted Recruitment of Esa1 Histone Acetylase

2000 • 286 citations

Cell cycle-regulated histone acetylation required for expression of the yeast HO gene

1999 • 275 citations

Activation Domain–Mediated Targeting of the SWI/SNF Complex to Promoters Stimulates Transcription from Nucleosome Arrays

1999 • 245 citations

Global Role for Chromatin Remodeling Enzymes in Mitotic Gene Expression

2000 • 232 citations

TBP-associated factors (TAF II s): multiple, selective transcriptional mediators in common complexes

2000 • 223 citations

The Something About Silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF_II30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)–FACT complex

2000 • 221 citations

Histone Acetylation at Promoters Is Differentially Affected by Specific Activators and Repressors

2001 • 207 citations

Gcn4 Activator Targets Gcn5 Histone Acetyltransferase to Specific Promoters Independently of Transcription

2000 • 201 citations

The Gcn5 bromodomain co-ordinates nucleosome remodelling

2000 • 194 citations

Distinct Classes of Yeast Promoters Revealed by Differential TAF Recruitment

2000 • 183 citations

TAF-Containing and TAF-Independent Forms of Transcriptionally Active TBP in Vivo

2000 • 173 citations

TFG3/TAF30/ANC1, a Component of the Yeast SWI/SNF Complex That Is Similar to the Leukemogenic Proteins ENL and AF-9

1996 • 158 citations

Transcriptional Activation by Gcn4p Involves Independent Interactions with the SWI/SNF Complex and the SRB/Mediator

1999 • 156 citations

Activation Domain-Specific and General Transcription Stimulation by Native Histone Acetyltransferase Complexes

1999 • 155 citations

A nucleosome precludes binding of the transcription factor Pho4 in vivo to a critical target site in the PHO5 promoter.

1994 • 134 citations

Chromatin remodelling at the PHO8 promoter requires SWI–SNF and SAGA at a step subsequent to activator binding

1999 • 133 citations

Structural and Functional Requirements for the Chromatin Transition at the PHO5 Promoter in Saccharomyces cerevisiae upon PHO5 Activation

1993 • 123 citations

Distribution of acetylated histones resulting from Gal4-VP16 recruitment of SAGA and NuA4 complexes

2000 • 122 citations

The transactivation domain of Pho4 is required for nucleosome disruption at the PHO5 promoter.

1994 • 121 citations

Continuous and widespread roles for the Swi-Snf complex in transcription

1999 • 106 citations

The nucleosome remodeling complex, Snf/Swi, is required for the maintenance of transcription invivo and is partially redundant with the histone acetyltransferase, Gcn5

1999 • 105 citations

Steady-state Levels of Histone Acetylation in Saccharomyces cerevisiae

2000 • 95 citations

Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC

1999 • 93 citations

ATP-Dependent Histone Octamer Mobilization and Histone Deacetylation Mediated by the Mi-2 Chromatin Remodeling Complex

2000 • 85 citations

Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae

2000 • 84 citations

Mediator–Nucleosome Interaction

2000 • 80 citations

Preferential Accessibility of the Yeast his3 Promoter Is Determined by a General Property of the DNA Sequence, Not by Specific Elements

2000 • 50 citations

Mediator?Nucleosome Interaction

2000 • 33 citations

Functional interaction of general transcription initiation factor TFIIE with general chromatin factor SPT16/CDC68

2000 • 17 citations