Degree of diversity of hepatitis C virus quasispecies and progression of liver disease

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

1987 • 59,130 citations

A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

1980 • 28,067 citations

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

1989 • 6,910 citations

CLUSTAL V: improved software for multiple sequence alignment

1992 • 2,421 citations

Classification of hepatitis C virus into six major genotypes and a series of subtypes by phylogenetic analysis of the NS-5 region

1993 • 1,401 citations

Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources

1992 • 1,288 citations

Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: Analysis by detection of antibody to hepatitis C virus

1990 • 1,236 citations

Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distribution

1992 • 938 citations

Selective Transmission of Human Immunodeficiency Virus Type-1 Variants from Mothers to Infants

1992 • 598 citations

The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance — a review

1985 • 523 citations

Selection for specific sequences in the external envelope protein of human immunodeficiency virus type 1 upon primary infection

1993 • 474 citations

Sequence variability in the 5' non-coding region of hepatitis C virus: identification of a new virus type and restrictions on sequence diversity

1993 • 437 citations

Genetic drift of hepatitis C virus during an 8.2-year infection in a chimpanzee: Variability and stability

1992 • 384 citations

Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus

1993 • 374 citations

Hepatogastroenterology

2011 • 323 citations

HIV-1 genomic rna diversification following sexual and parenteral virus transmission

1992 • 298 citations

Quantitation of relative fitness and great adaptability of clonal populations of RNA viruses

1991 • 278 citations

Long-term follow-up of non-A, non-B (type C) post-transfusion hepatitis

1992 • 270 citations

Quantification of hepatitis C virus by competitive reverse transcription—polymerase chain reaction: Increase of the virus in advanced liver disease

1993 • 257 citations

Non-A, Non-B Hepatitis in Chimpanzees and Marmosets

1981 • 203 citations

The evolutionary dynamics of HIV-1 quasispecies and the development of immunodeficiency disease

1990 • 195 citations

A Structurally Flexible and Antigenically Variable N-Terminal Domain of the Hepatitis C Virus E2/NS1 Protein: Implication for an Escape from Antibody

1993 • 186 citations

A unique, predominant hepatitis C virus variant found in an infant born to a mother with multiple variants

1993 • 145 citations

Evolution of sequences encoding the principal neutralization epitope of human immunodeficiency virus 1 is host dependent, rapid, and continuous.

1990 • 143 citations

Naturally occurring mutations within HIV-1 V3 genomic RNA lead to antigenic variation dependent on a single amino acid substitution

1991 • 140 citations

Implications of a quasispecies genome structure: effect of frequent, naturally occurring amino acid substitutions on the antigenicity of foot-and-mouth disease virus.

1989 • 124 citations

Fitness alteration of foot-and-mouth disease virus mutants: measurement of adaptability of viral quasispecies

1991 • 100 citations

Interferon-α in acute posttransfusion hepatitis C:. A randomized, controlled trial

1992 • 94 citations

Polymerase errors accumulating during natural evolution of the glycoprotein gene of vesicular stomatitis virus Indiana serotype isolates

1990 • 71 citations

Risk of hepatitis C virus infections through household contact with chronic carriers: Analysis of nucleotide sequences

1993 • 67 citations

Persistence of Viremia in Patients with Type-C Chronic Hepatitis during Long-Term Follow-up

1992 • 63 citations

High-risk groups and screening strategies for early detection of hepatocellular carcinoma in patients with chronic liver disease.

1993 • 45 citations

Sequence comparisons for a hepatitis C virus genome RNA isolated from a patient with liver cirrhosis

1992 • 31 citations

Sequence analysis of putative structural regions of hepatitis C virus isolated from 5 patients.

1991 • 4 citations