Human leukocyte elastase is an endogenous ligand for the integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) and modulates polymorphonuclear leukocyte adhesion.

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18).

1990 • 898 citations

Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies.

1983 • 674 citations

A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen.

1993 • 523 citations

ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions.

1995 • 507 citations

Complement receptor type three (CD11b/CD18) of human polymorphonuclear leukocytes recognizes fibrinogen.

1988 • 457 citations

The dynamic regulation of integrin adhesiveness

1994 • 456 citations

Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases.

1995 • 382 citations

Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells

1989 • 293 citations

Heparin is an adhesive ligand for the leukocyte integrin Mac-1 (CD11b/CD1).

1995 • 282 citations

The saturable high affinity association of factor X to ADP-stimulated monocytes defines a novel function of the Mac-1 receptor.

1988 • 279 citations

Transient adhesion of neutrophils to endothelium.

1989 • 279 citations

Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch.

1990 • 277 citations

Primary structure of human neutrophil elastase.

1987 • 227 citations

Antibody against the Leu-CAM beta-chain (CD18) promotes both LFA-1- and CR3-dependent adhesion events.

1992 • 223 citations

Adhesive receptor Mac-1 coordinates the activation of factor X on stimulated cells of monocytic and myeloid differentiation: an alternative initiation of the coagulation protease cascade.

1988 • 215 citations

Phorbol esters cause sequential activation and deactivation of complement receptors on polymorphonuclear leukocytes.

1986 • 206 citations

Regulation of vascular integrins [published erratum appears in Blood 1994 Apr 1;83(7):2013]

1993 • 199 citations

Specific antimononuclear phagocyte monoclonal antibodies. Application to the purification of dendritic cells and the tissue localization of macrophages.

1983 • 197 citations

Elastase and cathepsin G of human monocytes. Quantification of cellular content, release in response to stimuli, and heterogeneity in elastase-mediated proteolytic activity.

1989 • 185 citations

Two functional domains in the phagocyte membrane glycoprotein Mo1 identified with monoclonal antibodies.

1986 • 174 citations

Integrin modulating factor-1: A lipid that alters the function of leukocyte integrins

1992 • 163 citations

Antibiotic peptides and serine protease homologs in human polymorphonuclear leukocytes: defensins and azurocidin

1993 • 140 citations

Reperfusion-induced leukocyte infiltration: role of elastase

1990 • 137 citations

CAP37, a neutrophil-derived multifunctional inflammatory mediator

1995 • 97 citations

Human leukocyte elastase, cathepsin G, and lactoferrin: family of neutrophil granule glycoproteins that bind to an alveolar macrophage receptor.

1982 • 96 citations

Inflammation in the Lung in Cystic Fibrosis A Vicious Cycle That Does More Harm Than Good?

1990 • 93 citations

Endotoxin receptors (CD14) are found with CD16 (Fc gamma RIII) in an intracellular compartment of neutrophils that contains alkaline phosphatase.

1995 • 78 citations

Effects of human neutrophil elastase (HNE) on neutrophil function in vitro and in inflamed microvessels

1993 • 77 citations

Amino acid sequence of CAP37, a human neutrophil granule‐derived antibacterial and monocyte‐specific chemotactic glycoprotein structurally similar to neutrophil elastase

1990 • 74 citations

Use of monoclonal antibody against human neutrophil elastase in normal and leukaemic myeloid cells.

1988 • 66 citations

Structure of the Azurocidin, Proteinase 3, and Neutrophil Elastase Genes: Implications for Inflammation and Vasculitis

1994 • 65 citations

Isolation, characterization, and amino-terminal amino acid sequence analysis of human neutrophil cathepsin G from normal donors

1986 • 54 citations

Energetics of Leukocyte Integrin Activation

1995 • 54 citations

Complementary DNA sequence of human neutrophil azurocidin, an antibiotic with extensive homology to serine proteases

1991 • 52 citations

A fluorescence microassay for the quantitation of integrin-mediated adhesion of neutrophil

1994 • 43 citations

Monoclonal antibody to an activation neoepitope of alpha M beta 2 inhibits multiple alpha M beta 2 functions.

1994 • 32 citations

Expression of the human monocyte membrane antigen gp55 by murine fibroblasts after DNA-mediated gene transfer

1987 • 16 citations

Reversible Inactivation of Purified Leukocyte Integrin CR3 (CD11b/CD18, β_mβ₂) by Removal of Divalent Cations from a Cryptic Site

1995 • 15 citations