Vascular endothelium, haemostasis and thrombosis

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Modulation of endothelial cell hemostatic properties by tumor necrosis factor.

1986 • 1,335 citations

On the Regulation and Control of Fibrinolysis

1980 • 1,139 citations

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines.

1985 • 1,110 citations

Inherited Antithrombin Deficiency Causing Thrombophilia

1965 • 1,040 citations

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

1976 • 956 citations

The Anatomy and Physiology of Capillaries.

1929 • 853 citations

Human Endothelial Cells: Use of Heparin in Cloning and Long-Term Serial Cultivation

1983 • 801 citations

Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity.

1986 • 592 citations

Prostacyclin Synthesis Induced in Vascular Cells by Interleukin-1

1985 • 364 citations

Serial propagation of human endothelial cells in vitro.

1981 • 348 citations

Two different mechanisms in patients with venous thrombosis and defective fibrinolysis: low concentration of plasminogen activator or increased concentration of plasminogen activator inhibitor.

1985 • 341 citations

Acceleration of thrombin-antithrombin complex formation in rat hindquarters via heparinlike molecules bound to the endothelium.

1984 • 335 citations

Metabolism of adenine nucleotides by ectoenzymes of vascular endothelial and smooth-muscle cells in culture

1980 • 334 citations

Plasminogen activator inhibitor in the blood of patients with coronary artery disease.

1985 • 311 citations

Anticoagulantly active heparin-like molecules from vascular tissue

1984 • 248 citations

Uptake and metabolism of adenosine by pig aortic endothelial and smooth-muscle cells in culture

1978 • 243 citations

Self-regulation of procoagulant events on the endothelial cell surface.

1985 • 231 citations

Clearance of Thrombin from Circulation in Rabbits by High-affinity Binding Sites on Endothelium

1980 • 204 citations

Stimulation of prostaglandin production through purinoceptors on cultured porcine endothelial cells

1983 • 170 citations

Biosynthesis of von Willebrand protein by human endothelial cells. Identification of a large precursor polypeptide chain.

1983 • 166 citations

7 Thrombotic Thrombocytopenic Purpura and the Haemolytic-Uraemic Syndrome: Evolving Concepts of Pathogenesis and Therapy

1986 • 150 citations

Pharmacokinetics and systemic fibrinogenolytic effects of recombinant human tissue-type plasminogen activator (rt-PA) in humans.

1985 • 149 citations

THE DELAYED AND PROLONGED VASCULAR LEAKAGE IN INFLAMMATION. II. AN ELECTRON MICROSCOPIC STUDY OF THE VASCULAR RESPONSE AFTER THERMAL INJURY.

1965 • 142 citations

Transplantation of normal bone marrow into a pig with severe von Willebrand's disease.

1986 • 133 citations

Human and bovine endothelial cells synthesize membrane proteins similar to human platelet glycoproteins IIb and IIIa.

1985 • 131 citations

A monoclonal antibody to human platelet glycoprotein IIIa detects a related protein in cultured human endothelial cells.

1985 • 125 citations

Unidirectional transfer of prostaglandin endoperoxides between platelets and endothelial cells.

1984 • 122 citations

Effects of isolation and culture on prostaglandin synthesis by porcine aortic endothelial and smooth muscle cells

1982 • 120 citations

Modulation of the sis Gene Transcript During Endothelial Cell Differentiation in Vitro

1985 • 117 citations

Identification in vitro of an endothelial cell surface cofactor for antithrombin III. Parallel studies with isolated perfused rat hearts and microcarrier cultures of bovine endothelium.

1982 • 116 citations

Use of endothelium cultured on microcarriers as a model for the microcirculation.

1982 • 98 citations

Biosynthesis of the subunits of factor VIIIR by bovine aortic endothelial cells.

1983 • 77 citations

Masking of Fibrinolytic Response to Stimulation by an Inhibitor of Tissue-Type Plasminogen Activator in Plasma

1984 • 63 citations

Signals causing change in morphological phenotype, growth mode, and gene expression of vascular endothelial cells

1982 • 60 citations

Prostacyclin release stimulated by thrombin or bradykinin in porcine endothelial cells cultured from aorta and umbilical vein

1983 • 57 citations

Modulation of Rapid Plasminogen Activator Inhibitor in Plasma by Stanozolol

1984 • 53 citations

Serum-mediated suppression of cell-associated plasminogen activator activity in cultured endothelial cells

1980 • 51 citations

Microcarrier culture of vascular endothelial cells on solid plastic beads

1981 • 51 citations

3 Platelet and Vessel Wall Interaction and the Genesis of Atherosclerosis

1986 • 41 citations

SERPINS: ANTITHROMBIN AND OTHER INHIBITORS OF COAGULATION AND FIBRINOLYSIS. EVIDENCE FROM AMINO ACID SEQUENCES

1987 • 38 citations

2 The Multiple Levels of Endothelial Cell-Coagulation Factor Interactions

1986 • 32 citations

An in vitro model for the study of acute release of von Willebrand factor from human endothelial cells

1987 • 25 citations

Substrate for endothelial prostacyclin production in the presence of platelets exposed to collagen is derived from the platelets rather than the endothelium

1986 • 25 citations

Regulation of prostaglandin production and ectoenzyme activities in cultured aortic endothelial cells

1983 • 20 citations

5 The Natural Anticoagulants

1986 • 15 citations

Platelet products and vascular PGI2 production

1983 • 13 citations

INTERLEUKIN 1 (IL-1) AND TUMOR NECROSIS FACTOR (TNF) ACTIVATION OF VASCULAR ENDOTHELIUM: EFFECTS ON PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) AND TISSUE-TYPE PLASMINOGEN ACTIVATOR (tPA)

1987 • 11 citations

Protein C, isolation and potential use in prevention of thrombosis.

1987 • 9 citations

ENDOTHELIAL-DEPENDENT MECHANISMS OF LEUKOCYTE ADHESION: ROLE OF MONOKINES

1987 • 3 citations

Prolongation of Normotest Clotting Times in Rats on the Pill

1980 • 2 citations