Apoptotic Cleavage of Scaffold Attachment Factor A (SAF-A) by Caspase-3 Occurs at a Noncanonical Cleavage Site

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Programmed Cell Death in Animal Development

1997 • 2,690 citations

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1994 • 2,575 citations

A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B

1997 • 2,054 citations

Caspase-3 Is Required for DNA Fragmentation and Morphological Changes Associated with Apoptosis

1998 • 1,927 citations

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1996 • 1,902 citations

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

1993 • 1,144 citations

Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors

1998 • 984 citations

Suicidal Tendencies: Apoptotic Cell Death by Caspase Family Proteinases

1999 • 957 citations

Lamin proteolysis facilitates nuclear events during apoptosis.

1996 • 587 citations

Crystal structure of the cysteine protease interleukin-1β-converting enzyme: A (p20/p10)2 homodimer

1994 • 567 citations

Nuclear changes in apoptosis

1995 • 538 citations

Caspase-3 Is Required for α-Fodrin Cleavage but Dispensable for Cleavage of Other Death Substrates in Apoptosis

1998 • 484 citations

The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

1996 • 434 citations

Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death.

1994 • 424 citations

CD95(APO-1/Fas)-Mediated Apoptosis: Live and Let Die

1998 • 405 citations

Constitutive expression of the machinery for programmed cell death.

1996 • 386 citations

Dicing with death: dissecting the components of the apoptosis machinery

1994 • 363 citations

DNA-dependent protein kinase catalytic subunit: a target for an ICE-like protease in apoptosis.

1996 • 351 citations

Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis.

1996 • 270 citations

Characterization of SAF-A, a novel nuclear DNA binding protein from HeLa cells with high affinity for nuclear matrix/scaffold attachment DNA elements.

1992 • 255 citations

Structure of Recombinant Human CPP32 in Complex with the Tetrapeptide Acetyl-Asp-Val-Ala-Asp Fluoromethyl Ketone

1997 • 245 citations

Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosisin vivo

1998 • 244 citations

[43] Interleukin-1β converting enzyme

1994 • 208 citations

Nucleic‐acid‐binding properties of hnRNP‐U/SAF‐A, a nuclear‐matrix protein which binds DNA and RNA in vivo and in vitro

1994 • 168 citations

Cleavage of DFF-45/ICAD by Multiple Caspases Is Essential for Its Function during Apoptosis

1998 • 163 citations

The novel SAR-binding domain of scaffold attachment factor A (SAF-A) is a target in apoptotic nuclear breakdown

1997 • 138 citations

hnRNP proteins and B23 are the major proteins of the internal nuclear matrix of HeLa S3 cells

1996 • 121 citations

Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes

1996 • 119 citations

Activation of protein kinase Cdelta in human myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine

1996 • 119 citations

The Scaffold/Matrix Attachment Region Binding Protein hnRNP-U (SAF-A) Is Directly Bound to Chromosomal DNA in Vivo: A Chemical Cross-Linking Study

1997 • 91 citations

Dynamic changes of NuMA during the cell cycle and possible appearance of a truncated form of NuMA during apoptosis

1996 • 68 citations

Purification of Two Isoforms of hnRNP-U and Characterization of Their Nucleic Acid Binding Activity

1994 • 56 citations

The DNA-dependent protein kinase catalytic subunit (p460) is cleaved during Fas-mediated apoptosis in Jurkat cells.

1997 • 49 citations

Spatial Organization of Four hnRNP Proteins in Relation to Sites of Transcription, to Nuclear Speckles, and to Each Other in Interphase Nuclei and Nuclear Matrices of HeLa Cells

1999 • 40 citations

Hyperphosphorylation of replication protein A middle subunit (RPA32) in apoptosis

1999 • 37 citations

Mass spectrometric mapping of ion channel proteins (porins) and identification of their supramolecular membrane assembly

1998 • 25 citations

Biochemical and morphological characterization of the nuclear matrix from apoptotic HL-60 cells

1999 • 24 citations