Involvement of 15-lipoxygenase in early stages of atherogenesis.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

Beyond Cholesterol

1989 • 6,533 citations

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

The role of lipid peroxidation and antioxidants in oxidative modification of LDL

1992 • 2,335 citations

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

1989 • 1,914 citations

Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.

1987 • 1,051 citations

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

1981 • 1,037 citations

The selenoenzyme phospholipid hydroperoxide glutathione peroxidase

1985 • 961 citations

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia.

1987 • 885 citations

Lipoproteins and Atherogenesis

1990 • 549 citations

Biochemical structural and functional properties of oxidized low-density lipoprotein

1990 • 536 citations

Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions.

1990 • 429 citations

A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.

1989 • 417 citations

Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts.

1991 • 386 citations

Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase.

1992 • 382 citations

Presence of a modified low density lipoprotein in humans.

1988 • 373 citations

Modified forms of low density lipoprotein and atherosclerosis

1993 • 348 citations

Oxygenation of biological membranes by the pure reticulocyte lipoxygenase.

1990 • 244 citations

Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages

1991 • 223 citations

Monocytic origin of foam cells in human atherosclerotic plaques

1984 • 202 citations

Enzymology and Physiology of Reticulocyte Lipoxygenase: Comparison with Other Lipoxygenases

1986 • 170 citations

Oxygenation of lipoproteins by mammalian lipoxygenases

1993 • 163 citations

Phospholipid Hydroperoxide Glutathione Peroxidase is a Seleno-Enzyme Distinct from the Classical Glutathione Peroxidase as Evident from Cdna and Amino Acid Sequencing

1991 • 150 citations

Overexpression, purification and characterization of human recombinant 15-lipoxygenase

1993 • 136 citations

Activated human monocytes oxidize low-density lipoprotein by a lipoxygenase-dependent pathway.

1990 • 132 citations

Lipids of human atheroma Part 5. The occurrence of a new group of polar sterol esters in various stages of human atherosclerosis

1971 • 106 citations

Cellular oxidative modification of low density lipoprotein does not require lipoxygenases.

1992 • 101 citations

Occurrence of lipoxygenase products in membranes of rabbit reticulocytes. Evidence for a role of the reticulocyte lipoxygenase in the maturation of red cells.

1990 • 100 citations

The LDL receptor pathway delivers arachidonic acid for eicosanoid formation in cells stimulated by platelet-derived growth factor

1990 • 94 citations

Do 15-lipoxygenases have a common biological role?

1991 • 65 citations

Increased levels of monohydroxy metabolites of arachidonic acid and linoleic acid in LDL and aorta from atherosclerotic rabbits

1991 • 54 citations

The induced lipoxygenase in atherosclerotic aorta converts linoleic acid to the platelet chemorepellant factor 13-hode

1989 • 46 citations

Studies on fine structure and location of lipids in quick-freeze replicas of atherosclerotic aorta of WHHL rabbits

1987 • 39 citations

Differential low density lipoprotein receptor-dependent formation of eicosanoids in human blood-derived monocytes.

1992 • 35 citations

Atherosclerosis and molecular pathology: Mechanisms of cholesteryl ester accumulation in foam cells and extracellular space of atherosclerotic lesions.

1990 • 16 citations