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Higher plasma interleukin-6 (IL-6) level is associated with SSRI- or SNRI-refractory depression

Data up to Jan 2025

Published2009
Citations207
References51
Clinical Trials (1)

Total Citations Per Year

Abstract

References (51)

A RATING SCALE FOR DEPRESSION

1960 • 30,921 citations

The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10

1998 • 18,763 citations

Diagnostic and Statistical Manual of Mental Disorders

2009 • 11,002 citations

The mini international neuropsychiatric interview

1998 • 5,785 citations

Evaluation of Outcomes With Citalopram for Depression Using Measurement-Based Care in STAR*D: Implications for Clinical Practice

2006 • 3,604 citations

The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation

1995 • 2,525 citations

A Molecular and Cellular Theory of Depression

1997 • 2,091 citations

Glucocorticoids and Hippocampal Atrophy in Neuropsychiatric Disorders

2000 • 1,927 citations

Cytokines and major depression

2005 • 1,204 citations

Serum Brain-Derived Neurotrophic Factor, Depression, and Antidepressant Medications: Meta-Analyses and Implications

2008 • 1,167 citations

Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus

1996 • 1,104 citations

Evidence for an immune response in major depression: A review and hypothesis

1995 • 954 citations

The impact of age, weight and gender on BDNF levels in human platelets and plasma

2004 • 776 citations

Cytokines and the Brain: Implications for Clinical Psychiatry

2000 • 767 citations

Neuronal plasticity and survival in mood disorders

2000 • 658 citations

Postpartum mood disorders: diagnosis and treatment guidelines.

1998 • 597 citations

Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF

1996 • 583 citations

The Proinflammatory Cytokines Interleukin-1beta and Tumor Necrosis Factor-Alpha Activate Serotonin Transporters

2006 • 517 citations

Indicators of immune activation in major depression

1996 • 387 citations

Interleukin-6-(IL-6) plasma levels in depression and schizophrenia: comparison between the acute state and after remission

1997 • 359 citations

Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy

2006 • 341 citations

Cytokines: abnormalities in major depression and implications for pharmacological treatment

2004 • 319 citations

The pathogenesis of clinical depression: Stressor- and cytokine-induced alterations of neuroplasticity

2005 • 317 citations

Association of Interleukin‐6 and Other Biologic Variables with Depression in Older People Living in the Community

1999 • 286 citations

Hypothalamic-pituitary-adrenal axis activation and stimulation of systemic vasopressin secretion by recombinant interleukin-6 in humans: potential implications for the syndrome of inappropriate vasopressin secretion.

1994 • 251 citations

Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-α and ribavirin treatment

2008 • 226 citations

Acute phase proteins in major depression

1997 • 212 citations

Effects of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers

2000 • 205 citations

Depressive and anxiety symptoms in the early puerperium are related to increased degradation of tryptophan into kynurenine, a phenomenon which is related to immune activation

2002 • 198 citations

The possible role of neurotrophins in the pathogenesis and therapy of schizophrenia

2005 • 195 citations

Effects of paroxetine or milnacipran on serum brain-derived neurotrophic factor in depressed patients

2007 • 175 citations

Depression, comorbidities and the TNF-α system

2008 • 171 citations

Diagnosis and management of patients with bipolar II disorder.

2005 • 167 citations

Effects of interferon-α, interferon-γ and cAMP on the transcriptional regulation of the serotonin transporter

1998 • 163 citations

Combining Serotonin Reuptake Inhibitors and Bupropion in Partial Responders to Antidepressant Monotherapy

1997 • 161 citations

Depression : neurobiological, psychopathological, and therapeutic advances

1997 • 136 citations

Cytokines

1998 • 135 citations

Enhancement of serotonin transporter function by tumor necrosis factor alpha but not by interleukin-6

1998 • 131 citations

Hypothalamic-pituitary-adrenal axis activation and stimulation of systemic vasopressin secretion by recombinant interleukin-6 in humans: potential implications for the syndrome of inappropriate vasopressin secretion

1994 • 130 citations

The use of antidepressant drugs in patients with heart disease.

1998 • 128 citations

Bupropion sustained release: side effect profile.

1998 • 125 citations

Reciprocal actions of interleukin‐6 and brain‐derived neurotrophic factor on rat and mouse primary sensory neurons

2000 • 115 citations

Increased Plasma Concentration of Brain-Derived Neurotrophic Factor With Electroconvulsive Therapy

2007 • 108 citations

Stress at work alters serum brain-derived neurotrophic factor (BDNF) levels and plasma 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in healthy volunteers: BDNF and MHPG as possible biological markers of mental stress?

2007 • 99 citations

Dexamethasone augmentation in treatment‐resistant depression

1997 • 82 citations

Bone Mineral Density, Bone Turnover, and Osteoprotegerin in Depressed Women With and Without Borderline Personality Disorder

2006 • 65 citations

CELLULAR MECHANISMS IN THE VULNERABILITY TO DEPRESSION AND RESPONSE TO ANTIDEPRESSANTS

2000 • 54 citations

The use of thyroid supplements to augment antidepressant medication.

1998 • 45 citations

<i>Interleukin-6</i> Genetic Polymorphism and Chinese Major Depression

2005 • 24 citations

Addition of risperidone to sertraline improves sertraline‐resistant refractory depression without influencing plasma concentrations of sertraline and desmethylsertraline

2008 • 17 citations

Depression and Immunity

1998 • 8 citations

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