Glucocorticoids and Hippocampal Atrophy in Neuropsychiatric Disorders

How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*

2000 • 6,211 citations

Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

1984 • 3,073 citations

Subgenual prefrontal cortex abnormalities in mood disorders

1997 • 2,646 citations

Learning enhances adult neurogenesis in the hippocampal formation

1999 • 2,134 citations

A Molecular and Cellular Theory of Depression

1997 • 2,091 citations

Hippocampal atrophy in recurrent major depression.

1996 • 1,884 citations

Stress and cognitive function

1995 • 1,830 citations

Memory and Brain

1987 • 1,821 citations

Trauma and the Vietnam War generation: report of findings from the National Vietnam Veterans Readjustment Study

1990 • 1,683 citations

Hippocampal Volume Reduction in Major Depression

2000 • 1,645 citations

Cortisol levels during human aging predict hippocampal atrophy and memory deficits

1998 • 1,613 citations

MRI-based measurement of hippocampal volume in patients with combat- related posttraumatic stress disorder

1995 • 1,567 citations

Glial reduction in the subgenual prefrontal cortex in mood disorders

1998 • 1,497 citations

Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression∗∗See accompanying Editorial, in this issue.

1999 • 1,450 citations

Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus

1995 • 1,429 citations

Depression Duration But Not Age Predicts Hippocampal Volume Loss in Medically Healthy Women with Recurrent Major Depression

1999 • 1,371 citations

Why Stress Is Bad for Your Brain

1996 • 1,302 citations

Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report

1997 • 1,264 citations

Hippocampal volume in women victimized by childhood sexual abuse

1997 • 919 citations

Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder

1996 • 893 citations

Depression and memory impairment: A meta-analysis of the association, its pattern, and specificity.

1995 • 850 citations

Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing's syndrome

1992 • 831 citations

Regulation of adult neurogenesis by excitatory input and NMDA receptor activation in the dentate gyrus

1995 • 738 citations

Stress, Glucocorticoids, and Damage to the Nervous System: The Current State of Confusion

1996 • 737 citations

Developmental traumatology part I: biological stress systems∗∗See accompanying Editorial, in this issue.

1999 • 735 citations

Restoring production of hippocampal neurons in old age

1999 • 717 citations

Does stress damage the brain?

1999 • 694 citations

Serial CSF Corticotropin-Releasing Hormone Levels and Adrenocortical Activity in Combat Veterans With Posttraumatic Stress Disorder

1999 • 526 citations

Low Urinary Cortisol Excretion in Patients with Posttraumatic Stress Disorder

1990 • 523 citations

Selective Loss of Hippocampal Granule Cells in the Mature Rat Brain After Adrenalectomy

1989 • 520 citations

Enhanced suppression of cortisol following dexamethasone administration in posttraumatic stress disorder

1993 • 515 citations

Glucocorticoids, stress, and their adverse neurological effects: relevance to aging

1999 • 502 citations

Low urinary cortisol excretion in Holocaust survivors with posttraumatic stress disorder

1995 • 476 citations

Amygdala core nuclei volumes are decreased in recurrent major depression

1998 • 471 citations

Deficits in short-term memory in posttraumatic stress disorder

1993 • 465 citations

Quantitative Cerebral Anatomy in Depression

1993 • 458 citations

Dose-Response Changes in Plasma Cortisol and Lymphocyte Glucocorticoid Receptors Following Dexamethasone Administration in Combat Veterans With and Without Posttraumatic Stress Disorder

1995 • 452 citations

Decrease in cortisol reverses human hippocampal atrophy following treatment of Cushing’s disease

1999 • 450 citations

Urinary Free-Cortisol Levels in Posttraumatic Stress Disorder Patients

1986 • 437 citations

Effect of previous trauma on acute plasma cortisol level following rape

1995 • 417 citations

Subcortical and temporal structures in affective disorder and schizophrenia: A magnetic resonance imaging study

1992 • 410 citations

Abuse-Related Posttraumatic Stress Disorder

1995 • 409 citations

Cortical grey matter reductions associated with treatment-resistant chronic unipolar depression

1998 • 401 citations

Neuronal Loss in Hippocampus Induced by Prolonged Ethanol Consumption in Rats

1980 • 396 citations

Magnetic Resonance Imaging of the Caudate Nuclei in Depression

1992 • 361 citations

Enhanced Dexamethasone Suppression of Plasma Cortisol in Adult Women Traumatized by Childhood Sexual Abuse

1997 • 348 citations

Deficits in short-term memory in adult survivors of childhood abuse

1995 • 317 citations

Twenty-four hour urinary cortisol and catecholamine excretion in combat-related posttraumatic stress disorder

1990 • 300 citations

Hypercortisolemia and hippocampal changes in depression

1993 • 284 citations

Glucocorticoid Receptor-Mediated Cell Cycle Arrest Is Achieved through Distinct Cell-Specific Transcriptional Regulatory Mechanisms

1997 • 266 citations

Lower precombat intelligence is a risk factor for posttraumatic stress disorder.

1998 • 261 citations

A magnetic resonance imaging study of putamen nuclei in major depression

1991 • 259 citations

Cortical magnetic resonance imaging changes in elderly inpatients with major depression

1991 • 258 citations

Controversies surrounding glucocorticoid-mediated cell death in the hippocampus

1997 • 256 citations

Magnetic Resonance Imaging and Mood Disorders

1995 • 232 citations

Hippocampal formation size in normal human aging: a correlate of delayed secondary memory performance.

1994 • 197 citations

Chronic stress and posttraumatic stress disorders.

1986 • 168 citations

A twin study of the effects of the Vietnam War on posttraumatic stress disorder

1990 • 156 citations

Hippocampal/amygdala volumes in geriatric depression

1999 • 155 citations

Trauma And The Vietnam War Generation: Report Of Findings From The National Vietnam Veterans Readjustment Study

1990 • 142 citations

Cellular and Molecular Actions of Lamotrigine: Possible Mechanisms of Efficacy in Bipolar Disorder

1998 • 130 citations

Neuropsychological Deficits in Cushing??s Syndrome

1980 • 128 citations

Neurological status of Vietnam veterans with chronic posttraumatic stress disorder

1993 • 109 citations

High Incidence of Cortical Atrophy of the Cerebral and Cerebellar Hemispheres in Cushing's Disease

1971 • 101 citations

Chapter 26 Re-examination of the glucocorticoid hypothesis of stress and aging

1992 • 100 citations

Relationships between brain ct scan findings and cortisol in psychotic and nonpsychotic depressed patients

1989 • 99 citations

The DST and posttraumatic stress disorder

1987 • 83 citations

Glucocorticoid Inhibition of Fibroblast Proliferation and Regulation of the Cyclin Kinase Inhibitor p21Cip1

1997 • 83 citations

Predictors of Cortisol and 3-Methoxy-4-Hydroxyphenylglycol Responses in the Acute Aftermath of Rape

1998 • 77 citations

Absence of Striatal Volume Differences Between Depressed Subjects With No Comorbid Medical Illness and Matched Comparison Subjects

1999 • 58 citations

Young neurons for old brains?

1998 • 37 citations

Resorption of peritumoural oedema in cerebral gliomas during dexamethasone treatment evaluated by NMR relaxation time imaging

1993 • 28 citations

STUDIES ADRENAL FUNCTION IN COMBAT AND WOUNDED SOLDIERS

1955 • 22 citations

Elevated baseline and postdexamethasone cortisol levels

1987 • 21 citations

Effects of steroids on behavior, electrophysiology, water content and intracranial pressure in cerebral cytotoxic edema

1978 • 7 citations

Recent advancements in epilepsy

1997 • 4 citations

Lamotrigine — An Effective Mood Stabilizer?

1999 • 2 citations