Accuracy of in Vivo Aminoacylation Requires Proper Balance of tRNA and Aminoacyl-tRNA Synthetase

Experiments in molecular genetics

1972 • 28,260 citations

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

1978 • 4,472 citations

Plasmid vectors for high-efficiency expression controlled by the promoter of coliphage lambda

1981 • 664 citations

AMINOACYL tRNA SYNTHETASES: GENERAL SCHEME OF STRUCTURE-FUNCTION RELATIONSHIPS IN THE POLYPEPTIDES AND RECOGNITION OF TRANSFER RNAS

1987 • 535 citations

The frequency of errors in protein biosynthesis

1972 • 396 citations

Changing the Identity of a tRNA by Introducing a G-U Wobble Pair Near the 3′ Acceptor End

1988 • 344 citations

Lac repressor is a transient gene-activating protein

1987 • 123 citations

Quantities of individual aminoacyl-tRNA families and their turnover in Escherichia coli

1984 • 91 citations

Organization and structure of an E. coli tRNA operon containing seven tRNA genes

1981 • 84 citations

Escherichia coli glutaminyl-tRNA synthetase. I. Isolation and DNA sequence of the glnS gene.

1982 • 81 citations

Overproduction and purification of Escherichia coli tRNAGln2 and its use in crystallization of the glutaminyl-tRNA synthetase-tRNAGln complex

1988 • 79 citations

Discrimination between glutaminyl-tRNA synthetase and seryl-tRNA synthetase involves nucleotides in the acceptor helix of tRNA.

1988 • 77 citations

Intrinsic Precision of Aminoacyl-tRNA Synthesis Enhanced through Parallel Systems of Ligands

1972 • 76 citations

Cysteinyl-tRNA synthetase from Escherichia coli does not need an editing mechanism to reject serine and alanine. High binding energy of small groups in specific molecular interactions

1979 • 74 citations

Aminoacyl-tRNA synthetases from yeast: generality of chemical proofreading in the prevention of misaminoacylation of tRNA

1978 • 60 citations

Chain-extended Crystallization of Polyethylene

1972 • 58 citations

Transfer RNA mischarging mediated by a mutant Escherichia coli glutaminyl-tRNA synthetase.

1984 • 52 citations

Identification of transfer RNA suppressors in Escherichia coli

1979 • 31 citations

Identiflcation of clones anE.colitRNA^phegene by suppression of pheylananyl-tRNA synthetase thermosensitive mutants

1983 • 18 citations

Two control systems modulate the level of glutaminyl-tRNA synthetase in Escherichia coli

1985 • 16 citations

Escherichia coli glutaminyl-tRNA synthetase: a single amino acid replacement relaxes rRNA specificity.

1988 • 14 citations

Theories of enzyme specificity and their application to proteases and aminoacyl-Transfer RNA synthetases

1976 • 12 citations

Integrated function of a kinetic proofreading mechanism: double-stage proofreading by isoleucyl-tRNA synthetase

1986 • 8 citations

[Superspecificity of aminoacyl-tRNA-synthases].

1984 • 2 citations