Pharmacological sensitivity of ATP release triggered by photoliberation of inositol‐1,4,5‐trisphosphate and zero extracellular calcium in brain endothelial cells

Intercellular Calcium Signaling in Astrocytes via ATP Release through Connexin Hemichannels

2002 • 836 citations

Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells.

1995 • 821 citations

ATP Released from Astrocytes Mediates Glial Calcium Waves

1999 • 794 citations

Inflammatory mediators and modulation of blood-brain barrier permeability.

2000 • 769 citations

Connexins regulate calcium signaling by controlling ATP release

1998 • 767 citations

Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture

2001 • 530 citations

Purinergic signalling: ATP release.

2001 • 505 citations

Storage and Release of ATP from Astrocytes in Culture

2003 • 489 citations

The multidrug resistance (mdr1) gene product functions as an ATP channel.

1993 • 372 citations

The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel.

1994 • 354 citations

Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation.

1996 • 328 citations

Properties and regulation of gap junctional hemichannels in the plasma membranes of cultured cells.

1996 • 327 citations

Intercellular calcium signaling mediated by point-source burst release of ATP

2002 • 316 citations

Niflumic and flufenamic acids are potent reversible blockers of Ca2(+)-activated Cl- channels in Xenopus oocytes.

1990 • 309 citations

Physiological Role of Gap-Junctional Hemichannels

2000 • 305 citations

Voltage gating and permeation in a gap junction hemichannel.

1996 • 304 citations

Deformation-induced ATP release from red blood cells requires CFTR activity

1998 • 288 citations

Central role of heterocellular gap junctional communication in endothelium‐dependent relaxations of rabbit arteries

1998 • 284 citations

Hemi‐gap‐junction channels in solitary horizontal cells of the catfish retina.

1992 • 276 citations

Evidence That Release of Adenosine Triphosphate From Endothelial Cells During Increased Shear Stress Is Vesicular

2001 • 264 citations

Connexin-43 Hemichannels Opened by Metabolic Inhibition

1999 • 263 citations

Bioluminescence detection of ATP release mechanisms in epithelia

1998 • 242 citations

Properties of a nonjunctional current expressed from a rat connexin46 cDNA in Xenopus oocytes.

1993 • 235 citations

A release mechanism for stored ATP in ocular ciliary epithelial cells

1998 • 233 citations

How to Close a Gap Junction Channel: Efficacies and Potencies of Uncoupling Agents

2003 • 222 citations

Direct Observation of Calcium-Independent Intercellular ATP Signaling in Astrocytes

2000 • 216 citations

Volume-Dependent Atp-Conductive Large-Conductance Anion Channel as a Pathway for Swelling-Induced Atp Release

2001 • 212 citations

Nitric oxide induces rapid, calcium‐dependent release of vesicular glutamate and ATP from cultured rat astrocytes

2002 • 201 citations

Connexin mimetic peptides: specific inhibitors of gap-junctional intercellular communication

2001 • 196 citations

Flufenamic acid, mefenamic acid and niflumic acid inhibit single nonselective cation channels in the rat exocrine pancreas

1990 • 196 citations

Cystic Fibrosis Transmembrane Conductance Regulator Facilitates ATP Release by Stimulating a Separate ATP Release Channel for Autocrine Control of Cell Volume Regulation

2001 • 195 citations

1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities

1993 • 195 citations

Metabolic Inhibition Activates a Non-selective Current Through Connexin Hemichannels in Isolated Ventricular Myocytes

2000 • 190 citations

Increased release of ATP from endothelial cells during acute inflammation

1998 • 185 citations

The endothelial component of cannabinoid‐induced relaxation in rabbit mesenteric artery depends on gap junctional communication

1999 • 166 citations

Fenamates: a novel class of reversible gap junction blockers.

2001 • 157 citations

SV40 large T immortalised cell lines of the rat blood-brain and blood-retinal barriers retain their phenotypic and immunological characteristics

1996 • 155 citations

Photoliberating inositol-1,4,5-trisphosphate triggers ATP release that is blocked by the connexin mimetic peptide gap 26

2003 • 154 citations

Block of current through T‐type calcium channels by trivalent metal cations and nickel in neural rat and human cells.

1993 • 152 citations

Inhibition of Gap Junction Hemichannels by Chloride Channel Blockers

2002 • 151 citations

Noradrenaline and ATP: cotransmitters and neuromodulators.

1995 • 141 citations

Visualization and functional blocking of gap junction hemichannels (connexons) with antibodies against external loop domains in astrocytes

1998 • 132 citations

Gap junction gating sensitivity to physiological internal calcium regardless of pH in Novikoff hepatoma cells

1993 • 130 citations

Gating of cx46 gap junction hemichannels by calcium and voltage

1999 • 119 citations

Expression of chimeric connexins reveals new properties of the formation and gating behavior of gap junction channels

1994 • 118 citations

Connexin mimetic peptides reversibly inhibit Ca²⁺signaling through gap junctions in airway cells

2000 • 118 citations

Involvement of Rho‐kinase and tyrosine kinase in hypotonic stress‐induced ATP release in bovine aortic endothelial cells

2001 • 102 citations

Astrocyte–endothelial cell calcium signals conveyed by two signalling pathways

2001 • 101 citations

Cell swelling-induced ATP release and gadolinium-sensitive channels

2002 • 97 citations

Components of Astrocytic Intercellular Calcium Signaling

2000 • 87 citations

Dual Mechanism of Intercellular Communication in HOBIT Osteoblastic Cells: A Role for Gap-Junctional Hemichannels

2001 • 83 citations

The ion selectivity of a membrane conductance inactivated by extracellular calcium in Xenopus oocytes

1998 • 82 citations

Effects of connexin-mimetic peptides on nitric oxide synthase- and cyclooxygenase-independent renal vasodilation

2002 • 78 citations

Relative Contributions of NO and Gap Junctional Communication to Endothelium-Dependent Relaxations of Rabbit Resistance Arteries Vary with Vessel Size

2002 • 78 citations

Evidence for hemi‐gap junctional channels in isolated horizontal cells of the skate retina

1993 • 77 citations

Selective inhibition of gap junction channel activity by synthetic peptides

1999 • 74 citations

ATP stimulates Ca²⁺oscillations and contraction in airway smooth muscle cells of mouse lung slices

2002 • 73 citations

Open channel block by gadolinium ion of the stretch-inactivated ion channel in mdx myotubes

1991 • 65 citations

Connexin hemichannels and cell-cell channels: comparison of properties

2000 • 51 citations

Stretch-activated single K ⁺ channels account for whole-cell currents elicited by swelling

1999 • 41 citations

Hypotonic treatment evokes biphasic ATP release across the basolateral membrane of cultured renal epithelia (A6)

2002 • 39 citations

Intercellular communication upon mechanical stimulation of CPAE- endothelial cells is mediated by nucleotides

2001 • 37 citations

Gating of gap junction channels as revealed in cells stably transfected with wild type and mutant connexin cDNAs

1992 • 35 citations

Gap junctions and connexins: potential contributors to the immunological synapse

2002 • 33 citations

Endothelium-dependent regulation of cerebrovascular tone by extracellular and intracellular ATP

1997 • 30 citations

ATP release caused by bradykinin, substance P and histamine from intact and cultured smooth muscles of guinea-pig vas deferens

1998 • 27 citations

Fenamates inhibit contraction of guinea-pig isolated bronchus in vitro independent of prostanoid synthesis inhibition

1998 • 26 citations

Inositol(1,4,5)trisphosphate signal triggers a receptor-mediated ATP release

2002 • 20 citations

Nicorandil-induced ATP release in endothelial cells of rat caudal artery is associated with increase in intracellular Ca2+

2001 • 8 citations