Effect of chronic hyperghrelinemia on ingestive action of ghrelin

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

1999 • 8,261 citations

Ghrelin induces adiposity in rodents

2000 • 3,915 citations

A role for ghrelin in the central regulation of feeding

2001 • 3,415 citations

Ghrelin, a Novel Growth Hormone-Releasing Acylated Peptide, Is Synthesized in a Distinct Endocrine Cell Type in the Gastrointestinal Tracts of Rats and Humans¹

2000 • 1,794 citations

Prader-Willi Syndrome: Consensus Diagnostic Criteria

1993 • 1,279 citations

Stomach Is a Major Source of Circulating Ghrelin, and Feeding State Determines Plasma Ghrelin-Like Immunoreactivity Levels in Humans

2001 • 1,231 citations

Signals That Regulate Food Intake and Energy Homeostasis

1998 • 1,190 citations

Ghrelin Stimulates Gastric Acid Secretion and Motility in Rats

2000 • 875 citations

Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT

2002 • 734 citations

Elevated plasma ghrelin levels in Prader–Willi syndrome

2002 • 604 citations

Structure−Function Studies on the New Growth Hormone-Releasing Peptide, Ghrelin: Minimal Sequence of Ghrelin Necessary for Activation of Growth Hormone Secretagogue Receptor 1a

2000 • 546 citations

Ghrelin, A New Gastrointestinal Endocrine Peptide that Stimulates Insulin Secretion: Enteric Distribution, Ontogeny, Influence of Endocrine, and Dietary Manipulations

2002 • 525 citations

Antagonism of ghrelin receptor reduces food intake and body weight gain in mice

2003 • 480 citations

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2

1997 • 423 citations

Ghrelin and Des-Octanoyl Ghrelin Promote Adipogenesis Directly in Vivo by a Mechanism Independent of the Type 1a Growth Hormone Secretagogue Receptor

2003 • 417 citations

High Circulating Ghrelin: A Potential Cause for Hyperphagia and Obesity in Prader-Willi Syndrome

2002 • 343 citations

Peripheral ghrelin selectively increases Fos expression in neuropeptide Y – synthesizing neurons in mouse hypothalamic arcuate nucleus

2002 • 330 citations

Identification, Characterization, and Biological Activity of Specific Receptors for Natural (Ghrelin) and Synthetic Growth Hormone Secretagogues and Analogs in Human Breast Carcinomas and Cell Lines1

2001 • 329 citations

Identification and characterization of a novel gastric peptide hormone: The motilin-related peptide

2000 • 233 citations

Growth Hormone Releasing Peptides

1996 • 188 citations

Apelin, a New Enteric Peptide: Localization in the Gastrointestinal Tract, Ontogeny, and Stimulation of Gastric Cell Proliferation and of Cholecystokinin Secretion

2003 • 181 citations

Ghrelin—not just another stomach hormone

2002 • 169 citations

Unnatural Growth Hormone-Releasing Peptide Begets Natural Ghrelin

2001 • 164 citations

Growth Hormone Secretagogues: Physiological Role and Clinical Utility

1999 • 150 citations

Transgenic Mice Overexpressing Des-Acyl Ghrelin Show Small Phenotype

2004 • 147 citations

Desensitization studies using perifused rat pituitary cells show that growth hormone-releasing hormone and His-d-Trp-Ala-Trp-d-Phe-Lys-NH2 stimulate growth hormone release through distinct receptor sites

1991 • 146 citations

The endocrine response to acute ghrelin administration is blunted in patients with anorexia nervosa, a ghrelin hypersecretory state

2004 • 127 citations

Somatostatin Infusion Lowers Plasma Ghrelin without Reducing Appetite in Adults with Prader-Willi Syndrome

2004 • 126 citations

The Effects of Growth Hormone (GH)-Releasing Peptides on GH Secretion in Perifused Pituitary Cells of Adult Male Rats*

1984 • 106 citations

Twenty-four-hour growth hormone (GH)-releasing peptide (GHRP) infusion enhances pulsatile GH secretion and specifically attenuates the response to a subsequent GHRP bolus.

1993 • 106 citations

Novel hexarelin analogs stimulate feeding in the rat through a mechanism not involving growth hormone release

1998 • 93 citations

Parallel Studies of His-<scp>D</scp>Trp-Ala-Trp-<scp>D</scp>Phe-Lys-NH₂and Human Pancreatic Growth Hormone-Releasing Factor-44-NH₂in Rat Primary Pituitary Cell Monolayer Culture*

1985 • 90 citations

Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets.

1994 • 87 citations

Growth hormone secretagogues: characterization, efficacy, and minimal bioactive conformation.

1995 • 75 citations

Tissue-specific and insulin-dependent expression of a pancreatic amylase gene in transgenic mice.

1987 • 71 citations

Analysis of Rat Insulin II Promoter-Ghrelin Transgenic Mice and Rat Glucagon Promoter-Ghrelin Transgenic Mice

2005 • 71 citations

Nutrient inhibition of ghrelin secretion in the fasted rat

2003 • 68 citations

Variables Determining the Growth Hormone Response of His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂in the Rat*

1985 • 67 citations

Growth Hormone (GH) Secretion during Continuous Infusion of GH-Releasing Peptide: Partial Response Attenuation*

1991 • 53 citations

Central oxytocin potentiates excitatory responses of oxytocin neurones to stimulation of the dorsomedial hypothalamic nucleus in the suckled rat

2002 • 46 citations

Alterations in stomach ghrelin production and in ghrelin-induced growth hormone secretion in the aged rat

2004 • 34 citations

Altered Proglucagon Processing in an α-Cell Line Derived from Prohormone Convertase 2 Null Mouse Islets

2004 • 33 citations

Glucocorticoid regulation of growth hormone (GH) secretagogue-induced growth responses and GH secretagogue receptor expression in the rat

2000 • 29 citations

Pattern-Dependent Suppression of Growth Hormone (GH) Pulsatility by Ghrelin and GH-Releasing Peptide-6 in Moderately GH-Deficient Rats

2003 • 28 citations

Skeletal Growth Acceleration with Growth Hormone Secretagogues in Transgenic Growth Retarded Rats: Pattern‐Dependent Effects and Mechanisms of Desensitization

2001 • 26 citations