Ghrelin and Des-Octanoyl Ghrelin Promote Adipogenesis Directly in Vivo by a Mechanism Independent of the Type 1a Growth Hormone Secretagogue Receptor

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

1999 • 8,261 citations

Ghrelin induces adiposity in rodents

2000 • 3,915 citations

A role for ghrelin in the central regulation of feeding

2001 • 3,415 citations

Understanding Adipocyte Differentiation

1998 • 2,292 citations

Leptin Inhibits Bone Formation through a Hypothalamic Relay

2000 • 2,045 citations

The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

2003 • 1,617 citations

Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues

1997 • 1,137 citations

Ghrelin and Des-acyl Ghrelin: Two Major Forms of Rat Ghrelin Peptide in Gastrointestinal Tissue

2000 • 924 citations

A Null Mutation in Murine CD36 Reveals an Important Role in Fatty Acid and Lipoprotein Metabolism

1999 • 758 citations

Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT

2002 • 734 citations

Structure−Function Studies on the New Growth Hormone-Releasing Peptide, Ghrelin: Minimal Sequence of Ghrelin Necessary for Activation of Growth Hormone Secretagogue Receptor 1a

2000 • 546 citations

Peptidomimetic Regulation of Growth Hormone Secretion

1997 • 520 citations

Acute Central Ghrelin and GH Secretagogues Induce Feeding and Activate Brain Appetite Centers

2002 • 420 citations

Growth Hormone Secretagogue Binding Sites in Peripheral Human Tissues1

2000 • 418 citations

Systemic Administration of Ghrelin Induces Fos and Egr‐1 Proteins in the Hypothalamic Arcuate Nucleus of Fasted and Fed Rats

2000 • 352 citations

Peripheral ghrelin selectively increases Fos expression in neuropeptide Y – synthesizing neurons in mouse hypothalamic arcuate nucleus

2002 • 330 citations

Identification, Characterization, and Biological Activity of Specific Receptors for Natural (Ghrelin) and Synthetic Growth Hormone Secretagogues and Analogs in Human Breast Carcinomas and Cell Lines1

2001 • 329 citations

Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity

2002 • 290 citations

Cloning and Characterization of Two Human G Protein-Coupled Receptor Genes (GPR38 and GPR39) Related to the Growth Hormone Secretagogue and Neurotensin Receptors

1997 • 289 citations

Intravenous growth hormone: growth responses to patterned infusions in hypophysectomized rats

1985 • 282 citations

Immunocytochemical observation of ghrelin-containing neurons in the rat arcuate nucleus

2002 • 257 citations

Growth hormone-deficient dwarfism in the rat: a new mutation

1988 • 239 citations

Some histological methods: Trichrome staining and their preliminary technique

1929 • 238 citations

The Role of Ghrelin and Growth Hormone Secretagogues Receptor on Rat Adipogenesis

2003 • 233 citations

Identification and characterization of a novel gastric peptide hormone: The motilin-related peptide

2000 • 233 citations

Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity

2002 • 215 citations

High expression of leptin by human bone marrow adipocytes in primary culture

1998 • 204 citations

Identification, Characterization, and Biological Activity of Specific Receptors for Natural (Ghrelin) and Synthetic Growth Hormone Secretagogues and Analogs in Human Breast Carcinomas and Cell Lines

2001 • 185 citations

CD36 Mediates the Cardiovascular Action of Growth Hormone-Releasing Peptides in the Heart

2002 • 169 citations

Transcriptional Repression of pref-1by Glucocorticoids Promotes 3T3-L1 Adipocyte Differentiation

1999 • 151 citations

Ghrelin Can Bind to a Species of High Density Lipoprotein Associated with Paraoxonase

2003 • 149 citations

Body Weight and Fat Deposition in Prolactin Receptor-Deficient Mice**This work was supported in part by grants from the NICHD (HD-24192 to M.F.), the Juvenile Diabetes Foundation (196029 to M.F.), Eli Lilly & Co. (to M.F.), and INSERM (to P.A.K.).

2001 • 146 citations

Growth Hormone Secretagogue Receptor Family Members and Ligands

2001 • 137 citations

Ghrelin Acts on Leptin‐Responsive Neurones in the Rat Arcuate Nucleus

2002 • 129 citations

Glucocorticoids induce a drastic inhibition of proliferation and stimulate differentiation of adult rat fat cell precursors

1991 • 127 citations

The Effects of a Growth Hormone‐Releasing Peptide and Growth Hormone‐Releasing Factor in Conscious and Anaesthetized Rats

1989 • 123 citations

Effect of Food Restriction on Ghrelin in Normal‐Cycling Female Rats and in Pregnancy

2002 • 110 citations

Characterization of the Inhibitory Effect of Growth Hormone on Primary Preadipocyte Differentiation

1998 • 108 citations

Twenty-four-hour growth hormone (GH)-releasing peptide (GHRP) infusion enhances pulsatile GH secretion and specifically attenuates the response to a subsequent GHRP bolus.

1993 • 106 citations

Activation of the Hypothalamo-Pituitary-Adrenal Axis by the Growth Hormone (GH) Secretagogue, GH-Releasing Peptide-6, in Rats

1997 • 104 citations

Growth induced by pulsatile infusion of an amidated fragment of human growth hormone releasing factor in normal and GHRF-deficient rats

1985 • 95 citations

Specific binding sites for synthetic growth hormone secretagogues in non-tumoral and neoplastic human thyroid tissue

2000 • 94 citations

Growth Hormone (GH)-Independent Stimulation of Adiposity by GH Secretagogues

2001 • 84 citations

Dominant dwarfism in transgenic rats by targeting human growth hormone (GH) expression to hypothalamic GH-releasing factor neurons.

1996 • 81 citations

Bone marrow adipose tissue: Response to acute starvation

1979 • 78 citations

Bone Marrow Adipocytes: A Neglected Target Tissue for Growth Hormone

2002 • 73 citations

Interaction of the Growth Hormone-Releasing Peptides Ghrelin and Growth Hormone-Releasing Peptide-6 with the Motilin Receptor in the Rabbit Gastric Antrum

2003 • 61 citations

Prolactin receptor expression during adipocyte differentiation of bone marrow stroma.

1996 • 58 citations

Hypothalamic GH receptor gene expression in the rat: effects of altered GH status

1995 • 55 citations

Growth Hormone Treatment of Hypophysectomized Rats Increases Catecholamine‐induced Lipolysis and the Number of β‐Adrenergic Receptors in Adipocytes: No Differences in the Effects of Growth Hormone on Different Fat Depots

1996 • 37 citations

Effects of Growth Hormone Secretagogues in the Transgenic Growth-Retarded (Tgr) Rat

1997 • 32 citations

Hexarelin-induced growth hormone, cortisol, and prolactin release: a dose-response study.

1996 • 31 citations

Effects of Growth Hormone Secretagogues on Prolactin Release in Anesthetized Dwarf (dw/dw) Rats*

1998 • 28 citations

Pattern-Dependent Suppression of Growth Hormone (GH) Pulsatility by Ghrelin and GH-Releasing Peptide-6 in Moderately GH-Deficient Rats

2003 • 28 citations

Skeletal Growth Acceleration with Growth Hormone Secretagogues in Transgenic Growth Retarded Rats: Pattern‐Dependent Effects and Mechanisms of Desensitization

2001 • 26 citations

Growth hormone (GH) and insulin-like growth factor I responses after treatments with an orally active GH secretagogue L-163,255 in swine.

1996 • 18 citations

Effect of the GH secretagogue L-163,255 and restricted feeding time on GH pulsatility in the rat

2002 • 5 citations