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Rapid non-genomic and genomic responses to progestogens, estrogens, and glucocorticoids in the endocrine pancreatic B cell, the adipocyte and other cell types

Data up to Jan 2025

Published2002
Citations107
References213

Total Citations Per Year

Abstract

References (213)

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Identification and Characterization of Functional Nongenomic Progesterone Receptors on Human Sperm Membrane1

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Carbohydrate Metabolism During Pregnancy

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Cell surface localization of a novel non-genomic progesterone receptor on the head of human sperm

1991 • 141 citations

Estradiol binding to cell surface raises cytosolic free calcium in T cells

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Estradiol causes the rapid accumulation of cAMP in human prostate.

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Free calcium changes associated with hormone action in amphibian oocytes

1980 • 131 citations

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1970 • 131 citations

A review of carbohydrate metabolism and the oral contraceptives

1969 • 130 citations

Functional Antagonism of Gonadal Steroids at the 5-Hydroxytryptamine Type 3 Receptor

1998 • 125 citations

Cytoplasmic 17β-[3H]Estradiol Binding in Rat Adipose Tissues*

1978 • 123 citations

Modulation of corticotrophin-releasing factor release from hypothalamic synaptosomes

1974 • 118 citations

Use of receptor antibodies to demonstrate membrane glucocorticoid receptor in cells from human leukemic patients

1993 • 117 citations

Direct non-genomic effects of follicular steroids on maturing human oocytes: oestrogen versus androgen antagonism

1997 • 117 citations

Effect of Corticosterone on Insulin and Glucagon Secretion by the Isolated Perfused Rat Pancreas*

1980 • 114 citations

Progesterone receptor characterized by photoaffinity labelling in the plasma membrane of Xenopus laevis oocytes

1984 • 109 citations

Non‐genomic actions of 17β‐oestradiol in mouse pancreatic β‐cells are mediated by a cGMP‐dependent protein kinase

1999 • 105 citations

Intracellular calcium increase and acrosome reaction in response to progesterone in human spermatozoa are correlated with in-vitro fertilization

1995 • 105 citations

Endothelium-dependent relaxation of rat aorta and main pulmonary artery by the phytoestrogens genistein and daidzein

2000 • 104 citations

The potency of mu-opioid hyperpolarization of hypothalamic arcuate neurons is rapidly attenuated by 17 beta-estradiol

1994 • 104 citations

The Influence of Acute Physiological Increments of Cortisol on Fuel Metabolism and Insulin Binding to Monocytes in Normal Humans *

1980 • 102 citations

Differential effects of 17β‐estradiol and testosterone on the contractile responses of porcine coronary arteries

2000 • 102 citations

Cortisol rapidly reduces prolactin release and cAMP and 45Ca2+ accumulation in the cichlid fish pituitary in vitro.

1991 • 101 citations

Glucose Tolerance in Women Receiving an Ovulatory Suppressant

1964 • 99 citations

Selective expression of a progesterone receptor on the human sperm surface

1992 • 95 citations

Membrane Oestrogen Receptors on Rat Pituitary Tumour Cells: Immuno‐Identification and Responses to Oestradiol and Xenoestrogens

1999 • 94 citations

SPECIFIC INTERACTION OF CORTICOSTEROIDS WITH BINDING SITES IN THE PLASMA MEMBRANES OF THE RAT ANTERIOR PITUITARY GLAND

1978 • 94 citations

Inhibitory Effect of Prednisone on Insulin Secretion in Man: Model for Duplication of Blood Glucose Concentration

1975 • 92 citations

Identification of oestrogen receptors and oestrogen receptor mRNA in human adipose tissue

1996 • 91 citations

Effect of glucocorticoids on the glucose transport system of isolated fat cells.

1975 • 90 citations

Stimulation of prostate cancer growth by androgens and estrogens through the intermediacy of sex hormone-binding globulin.

1996 • 90 citations

The other estrogen receptor in the plasma membrane: implications for the actions of environmental estrogens.

1995 • 88 citations

DIABETOGENIC FACTORS ASSOCIATED WITH PREGNANCY.

1964 • 87 citations

Plasma insulin and blood glucose levels in patients taking oral contraceptives

1966 • 86 citations

Inhibition of Uterine Contractility by Progesterone and Progesterone Metabolites: Mediation by Progesterone and Gamma Amino Butyric AcidA Receptor Systems

1991 • 84 citations

Nongenomic Steroid Action: Independent Targeting of a Plasma Membrane Calcium Channel and a Tyrosine Kinase

1995 • 82 citations

Membrane Receptors for Corticosterone: A Mechanism for Rapid Behavioral Responses in an Amphibian

1994 • 80 citations

Structure and Function of the Gonadotropins

1978 • 79 citations

Effect of platelet-activating factor on motility and acrosome reaction of human spermatozoa

1994 • 77 citations

Effects of in vivo estrogen treatment on adipose tissue metabolism and nuclear estrogen receptor binding in isolated rat adipocytes

1992 • 76 citations

Rapid activation of endothelial nitric oxide synthase by estrogen

1999 • 75 citations

Progestin Enhancement of the Plasma Insulin Response to Glucose in Rhesus Monkeys

1969 • 75 citations

Mechanisms of 17 β‐oestradiol induced vasodilatation in isolated pressurized rat small arteries

2000 • 75 citations

Direct Effect of Corticosterone upon Insulin Secretion Studied by Three Different Techniques

1979 • 74 citations

Dexamethasone alters rapidly actin polymerization dynamics in human endometrial cells: Evidence for nongenomic actions involving cAMP turnover

1996 • 72 citations

Estrogen Acutely Stimulates Endothelial Nitric Oxide Synthase in H441 Human Airway Epithelial Cells

1999 • 72 citations

Withdrawal from the endogenous steroid progesterone results in GABAA currents insensitive to benzodiazepine modulation in rat CA1 hippocampus

1995 • 71 citations

The effect of glucose on insulin biosynthesis by isolated islets of langerhans of the rat

1970 • 68 citations

La reproduction chez les mammiferes et l'homme

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Estradiol Inhibits Smooth Muscle Cell Growth in Part by Activating the cAMP-Adenosine Pathway

2000 • 65 citations

Diabetes and Pregnancy

1963 • 65 citations

Membrane binding sites and non-genomic effects of estrogen in cultured human preosteoclastic cells

1996 • 64 citations

Progesterone induces Ca++-dependent 3',5'-cyclic adenosine monophosphate increase in human sperm.

1996 • 64 citations

Effects of norethindrone on carbohydrate and lipid metabolism.

1975 • 63 citations

Non‐genomic effects of progesterone on the signaling function of G protein‐coupled receptors

1999 • 61 citations

Cytoplasmic Progestin Binding in Rat Adipose Tissues*

1979 • 60 citations

Stimulation of platelet-activating factor synthesis by progesterone and A23187 in human spermatozoa

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A novel functional estrogen receptor on human sperm membrane interferes with progesterone effects

2000 • 58 citations

Studies of a plasma membrane steroid receptor in Xenopus oocytes using the synthetic progestin RU 486

1985 • 57 citations

Insulin Secretion in vitro by Pancreatic Tissue from Normal, Adrenalectomized, and Cortisol-Treated Rats.

1967 • 56 citations

Nongenomic effects of progesterone on human intestinal smooth muscle cells

1996 • 55 citations

[3H]Dexamethasone Binding to Plasma Membrane-Enriched Fractions from Liver of Nonadrenalectomized Rats*

1988 • 53 citations

Progesterone triggers rapid transmembrane calcium influx and/or calcium mobilization from endoplasmic reticulum, via a pertussis-insensitive G-protein in granulosa cells in relation to luteinization process

1996 • 53 citations

Functional studies of corticosterone receptors in neuronal membranes.

1995 • 52 citations

17β‐Oestradiol modulates in vitro electrical properties and responses to kainate of oxytocin neurones in lactating rats

2000 • 51 citations

Effect of estradiol on lipolysis and adenosine 3',5'-monophosphate accumulation in isolated rat adipocytes

1974 • 51 citations

Nongenomic progesterone receptor on human spermatozoa: biochemical aspects and clinical implications

1999 • 51 citations

Plasma insulin concentrations during prolonged work at near maximal oxygen uptake

1970 • 51 citations

Insulin biosynthesis: Effects of carbohydrates and related compounds

1969 • 48 citations

17β-Estradiolid Ca influx rapid Ca2+ prostate cancer cells

1996 • 48 citations

The effects of norgestrel on carbohydrate and lipid metabolism over one year

1976 • 47 citations

Progesterone induces capacitation in human spermatozoa

2009 • 46 citations

Progesterone-stimulated intracellular calcium increase in human spermatozoa is protein kinase C-independent

1998 • 45 citations

Stimulation of the phosphoinositide signalling system as a possible mechanism for glucocorticoid action in blood pressure control

1988 • 44 citations

Extragenomic actions of progesterone in human sperm and progesterone metabolites in human platelets

1999 • 44 citations

Membrane estrogen receptor-enriched GH3/B6 cells have an enhanced non-genomic response to estrogen

1995 • 43 citations

CARBOHYDRATE METABOLISM IN PREGNANCY

1960 • 42 citations

Inhibition by corticosterone of calcium inflow and insulin release in rat pancreatic islets

1984 • 42 citations

Specific interaction of corticosteroids with components of the cell membrane which are involved in the translocation of the hormone into the intravesicular space of purified rat liver plasma membrane vesicles

1980 • 41 citations

Enhanced relaxation of porcine coronary arteries after acute exposure to a physiological level of 17β‐estradiol involves non‐genomic mechanisms and the cyclic AMP cascade

2000 • 41 citations

Relationship between Sigma-like site and progesterone-binding site of adult male rat liver microsomes

1994 • 40 citations

The effects of a new oral contraceptive on gonadotropin excretion

1965 • 39 citations

Plasma insulin in normal midpregnancy

1965 • 39 citations

Immediate in-vivo effect of corticosterone on glucose-induced insulin secretion in the rat

1982 • 37 citations

Short-time effects of neuroactive steroids on rat cortical Ca2+-ATPase activity

1999 • 36 citations

Unusual steroid specificity of the cell surface progesterone receptor on human sperm.

1996 • 36 citations

Protein kinase A maintains cellular tolerance to mu opioid receptor agonists in hypothalamic neurosecretory cells with chronic morphine treatment: convergence on a common pathway with estrogen in modulating mu opioid receptor/effector coupling.

1998 • 36 citations

Progesterone induces Ca++-dependent 3',5'-cyclic adenosine monophosphate increase in human sperm

1996 • 35 citations

Management of endometriosis with nor-progesterone

1961 • 35 citations

PROGESTERONE AND INSULIN-RESISTANCE: STUDIES OF PROGESTERONE ACTION ON GLUCOSE TRANSPORT, LIPOGENESIS AND LIPOLYSIS IN ISOLATED FAT CELLS OF THE FEMALE RAT

1981 • 34 citations

Circulating Insulin and Tissular Reactivity to Insulin in the Rat During the Perinatal Period

1971 • 34 citations

Rheumatism and Arthritis: Review of American and English Literature of Recent Years: (Fifteenth Rheumatism Review)

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Stimulus-secretion coupling in porcine adrenal chromaffin cells: Acute effects of glucocorticoids

1999 • 33 citations

Effect of normal pregnancy on glucose assimilation, insulin and non-esterified fatty acids levels

1968 • 33 citations

Foetal Rat Pancreas in Organ Culture

1976 • 32 citations

Rapid activation of glycogen phosphorylase by steroid hormones in cultured rat hepatocytes

1989 • 32 citations

Direct long-term effect of hydrocortisone on insulin and glucagon release from mouse pancreatic islets in tissue culture

1981 • 32 citations

Specific binding sites for corticosterone in isolated cells and plasma membrane from rat liver

1991 • 32 citations

Glucocorticoid modulates Na+/H+ exchange activity in vascular smooth muscle cells by nongenomic and genomic mechanisms

2000 • 31 citations

Non-genomic effects of progesterone on human intestinal smooth muscle cells

1995 • 30 citations

Serum Progesterone and Immuno-Reactive Insulin Levels in the Pregnant Rat

1973 • 30 citations

Steroids decrease granulocyte membrane fluidity, while phorbol ester increases membrane fluidity

1990 • 30 citations

The metabolism and motility of human spermatozoa in the presence of steroid hormones and synthetic progestagens

1978 • 29 citations

Phospholipase C-? and ovarian sex steroids in pig granulosa cells

1999 • 29 citations

Plasma Glucose, Progesterone and Immunoreactive Insulin Levels in the Lactating Rat

1974 • 29 citations

Parallels in the Modes of Action of Peptide and Steroid Hormones: Membrane Effects and Cellular Entry

1978 • 27 citations

Electrophysiological effects of progesterone on hepatocytes

1995 • 27 citations

Effects of Oral Contraceptive Agents and Sex Steroids on Carbohydrate Metabolism

1972 • 26 citations

Effects of pregnancy and progesterone and/or oestradiol on the insulin secretion and pancreatic insulin content in the perfused rat pancreas.

1979 • 25 citations

Effect of Adrenocorticotropin and Glucocorticoids on Insulin Secretion1

1968 • 25 citations

Insulin binding and action in adipocytes of pregnant rats: evidence that insulin resistance is caused by post-receptor binding defects

1984 • 25 citations

Ovarian-adrenal interactions in regulation of endocrine pancreatic function in the rat

1983 • 24 citations

Characterization of progesterone-3-[125I-BSA] binding sites in the medial preoptic area and anterior hypothalamus

1995 • 24 citations

Preliminary report: effects of female sex hormones on insulin secretion by the perfused rat pancreas.

1976 • 21 citations

Progesterone and insulin-resistance in the pregnant rat. I. In vivo and in vitro studies.

1981 • 21 citations

Inhibition of granulocyte function by steroids is not limited to corticoids

1988 • 20 citations

Lens epithelia contain a high-affinity, membrane steroid hormone-binding protein.

1999 • 20 citations

Insulinemies Maternelles Et Foetales Chez Le Rat

1969 • 19 citations

Studies on the Anti-allergic Mechanism of Glucocorticoids in Mice.

1992 • 19 citations

Estrogen directly acts on osteoclasts via inhibition of inward rectifier K + channels

2000 • 18 citations

Bidirectional effects of the neuroactive steroid tetrahydrodeoxycorticosterone on GABA‐activated Cl− currents in cultured rat hypothalamic neurons

1999 • 18 citations

A Role for the Endogenous Opioid Peptides in the Regulation of Gonadotropin Secretion in the Primate

1987 • 16 citations

Radioligand Assays for Oestradiol and Progesterone Conjugated to Protein Reveal Evidence for a Common Membrane Binding Site in the Medial Preoptic Area‐Anterior Hypothalamus and Differential Modulation by Cholera Toxin and GTPγS

1999 • 16 citations

Effects of progesterone and 17-beta-oestradiol treatments on the pancreatic B cell castrated female rats. Biochemical variations.

1978 • 15 citations

Progesterone and synthetic steroids produce insulin resistance at the post-receptor level in adipocytes of female rats

1988 • 15 citations

Estradiol Conjugated to BSA Releases Oxytocin from Synaptosome-Containing Homogenates from the Medial Preoptic Area-Hypothalamus

1996 • 14 citations

Insulin secretion from isolated pancreatic islets in the female rat. Short and long term oestradiol influence.

1979 • 13 citations

Effect of estradiol on insulin secreting INS-1 cells overexpressing estrogen receptors

2000 • 11 citations

Lipolytic activity of progesterone and synthetic progestins on rat parametrial adipocytes in vitro.

1991 • 11 citations

Effects of hydrocortisone on transmembrane currents in guinea pig ventricular myocytes. Possible evidence for positive inotropism.

1994 • 11 citations

Progesterone and glucose metabolism in the female rat adipocyte: effect on hexokinase activity

1982 • 10 citations

News and views of non-genomic progesterone receptors on spermatozoa

2009 • 9 citations

Inhibition of glucose metabolism by progesterone in adipocytes: role of protein synthesis

1991 • 8 citations

Acute effects of progesterone on glucose metabolism in rat adipocytes: Are they modulated by endogenous adenosine?

1997 • 7 citations

Surr�nale et insulin�mie chez le rat II. Corticosurr�nale et insuline s�rique

1968 • 7 citations

The Effects of a "Low-Estrogen" Oral Contraceptive on Carbohydrate Metabolism During Six Months of Treatment: A Preliminary Report of Blood Glucose and Plasma Insulin Values

1977 • 6 citations

Effect of corticosterone upon insulin biosynthesis and storage by isolated rat Langerhans islets.

1982 • 5 citations

Carbohydrate metabolism of female rat adipocytes: effects and mechanisms of action of progesterone.

1986 • 5 citations

Adrenal interference of insulin secretion after 14-days oestradiol treatment in female rats

1984 • 5 citations

Modulation of the direct effect of corticosterone upon glucose-induced insulin secretion of rat isolated islets of Langerhans.

1981 • 4 citations

Effect of Calcium upon Insulin Inhibition Induced by Corticosterone in Isolated Langerhans Islets

1982 • 4 citations

Uptake of Progesterone by Red Blood Cells in the Rat1

1988 • 4 citations

Immediate, short- and long-term opposite effects of oestradiol-17β on glucose metabolism in rat adipocytes: relationship with the biphasic changes in body weight and food intake

1984 • 4 citations

Progesterone and insulin resistance. III. Time-course study of progesterone action on differentially labelled 14C-glucose utilization by adipose tissue and isolated adipocytes of the female rat.

1981 • 3 citations

A three hours study of the response of plasma corticosterone and of three liver enzymes in rats subjected to stress in the late afternoon or during the morning hours.

1978 • 3 citations

Salicylate inhibition of in vitro plasminogen activation by saline extracts of rat tissues

1974 • 3 citations

Effect of Corticosterone upon Response to L (-) Leucine of Isolated Rats Langerhans Islets

1981 • 2 citations

Immediate inhibition by corticosterone of 45Ca efflux from perifused rat islets

1983 • 2 citations

Simultaneous determination of insulin secretion and glucose oxidation rates during incubation of isolated rat islets of Langerhans.

1978 • 1 citations

Deleted Work

1955 • 0 citations

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