Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling

Permanent cell line expressing human factor VIII-related antigen established by hybridization.

1983 • 1,458 citations

Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ERα and ERβ Expressed in Chinese Hamster Ovary Cells

1999 • 1,046 citations

Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells.

1996 • 964 citations

Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen

1999 • 895 citations

Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells

1977 • 686 citations

Membrane estrogen receptors identified by multiple antibody labeling and impeded‐ligand binding

1995 • 532 citations

17β-Estradiol Regulation of Human Endothelial Cell Basal Nitric Oxide Release, Independent of Cytosolic Ca ²⁺ Mobilization

1997 • 482 citations

Rapid Membrane Effects of Steroids in Neuroblastoma Cells: Effects of Estrogen on Mitogen Activated Protein Kinase Signalling Cascade and c-fos Immediate Early Gene Transcription

1997 • 478 citations

Effects of 17beta-estradiol on cytokine-induced endothelial cell adhesion molecule expression.

1996 • 351 citations

Cell surface-binding sites for progesterone mediate calcium uptake in human sperm.

1991 • 291 citations

Fluid Shear Stress Stimulates Mitogen-Activated Protein Kinase in Endothelial Cells

1995 • 287 citations

Heterogeneity in endothelial cells from large vessels and microvessels

1987 • 237 citations

Rapid Activation of MAP Kinase by Estrogen in the Bone Cell Line

1997 • 225 citations

Estrogen Stimulates Heat Shock Protein 90 Binding to Endothelial Nitric Oxide Synthase in Human Vascular Endothelial Cells

2000 • 177 citations

Immediate and transient stimulation of protein tyrosine phosphorylation by estradiol in MCF-7 cells.

1993 • 117 citations

Chicken Ovalbumin Upstream Promoter-Transcription Factor Interacts with Estrogen Receptor, Binds to Estrogen Response Elements and Half-Sites, and Inhibits Estrogen-induced Gene Expression

1997 • 114 citations

Lymphocyte adhesion-dependent calcium signaling in human endothelial cells.

1995 • 103 citations

The other estrogen receptor in the plasma membrane: implications for the actions of environmental estrogens.

1995 • 88 citations

Steroids conjugated to bovine serum albumin as tools to demonstrate specific steroid neuronal membrane binding sites.

1996 • 83 citations

Smooth muscle cell responsiveness to nitrovasodilators in hypertensive and normotensive rats.

1994 • 51 citations

Evidence for a novel pituitary factor that potentiates the mitogenic effect of estrogen in human breast cancer cells.

1985 • 46 citations

Heterogeneous activation thresholds to cytokines in genetically distinct endothelial cells: evidence for diverse transcriptional responses.

1994 • 44 citations

Expression of human estrogen receptor mutants in Xenopus oocytes: correlation between transcriptional activity and ability to form protein-DNA complexes.

1988 • 42 citations

Expression of Estrogen Receptor α mRNA and Protein Variants in Human Endometrial Carcinoma

1999 • 38 citations

Use of a biotinyl-estradiol derivative to demonstrate estradiol-membrane binding sites on adherent human breast cancer MCF-7 cells.

1993 • 15 citations