Transcellular Transport of Organic Anions Across a Double-transfected Madin-Darby Canine Kidney II Cell Monolayer Expressing Both Human Organic Anion-transporting Polypeptide (OATP2/SLC21A6) and Multidrug Resistance-associated Protein 2 (MRP2/ABCC2)
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References (28)
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
1951 • 319,299 citations
A pharmacokinetic analysis program (multi) for microcomputer.
1981 • 2,465 citations
The Sister of P-glycoprotein Represents the Canalicular Bile Salt Export Pump of Mammalian Liver
1998 • 933 citations
Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance
1999 • 796 citations
Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver
2001 • 722 citations
Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells.
1999 • 663 citations
Molecular Identification and Characterization of Novel Members of the Human Organic Anion Transporter (OATP) Family
2000 • 636 citations
A Novel Human Hepatic Organic Anion Transporting Polypeptide (OATP2)
1999 • 630 citations
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.
1998 • 621 citations
Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver
2000 • 565 citations
Identification of a Novel Gene Family Encoding Human Liver-specific Organic Anion Transporter LST-1
1999 • 546 citations
Localization and Genomic Organization of a New Hepatocellular Organic Anion Transporting Polypeptide
2000 • 516 citations
Hepatic Uptake of Bilirubin and Its Conjugates by the Human Organic Anion Transporter SLC21A6
2001 • 507 citations
Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver
1997 • 352 citations
Hepatic Secretion of Conjugated Drugs and Endogenous Substances
2000 • 245 citations
Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes.
2001 • 211 citations
Vectorial Transport by Double-Transfected Cells Expressing the Human Uptake Transporter SLC21A8 and the Apical Export Pump ABCC2
2001 • 204 citations
Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump
2001 • 182 citations
Excretion of GSSG and Glutathione Conjugates Mediated by MRP1 and CM0AT/MRP2
1998 • 159 citations
Hepatobiliary transport
2000 • 146 citations
Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (rlst-1) in rat liver
2000 • 144 citations
Biliary excretion of pravastatin in rats: contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter.
1997 • 140 citations
Regulation of 2‐acetylaminofluorene‐and 3‐methylcholanthrene‐mediated induction of multidrug resistance and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver
1991 • 125 citations
The role of phospholipids in bile formation: what can we learn from animals and human disease?
2000 • 115 citations
Introduction: Transport across the hepatocyte canalicular membrane
1997 • 96 citations
Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole glucuronide.
1997 • 50 citations
Transfected rat cMOAT is functionally expressed on the apical membrane in Madin-Darby canine kidney (MDCK) cells.
1998 • 26 citations
The synthesis of taurine-conjugated bile acids and bile acid sulfates labeled with 14C or 3H in the taurine moiety
1997 • 9 citations