Introduction: Transport across the hepatocyte canalicular membrane

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

1987 • 2,788 citations

MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates Phosphatidylcholine

1996 • 863 citations

Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

1996 • 827 citations

Distribution of organelles and membranes between hepatocytes and nonhepatocytes in the rat liver parenchyma. A stereological study.

1977 • 827 citations

cDNA Cloning of the Hepatocyte Canalicular Isoform of the Multidrug Resistance Protein, cMrp, Reveals a Novel Conjugate Export Pump Deficient in Hyperbilirubinemic Mutant Rats

1996 • 641 citations

Phosphatidylcholine translocase: A physiological role for the mdr2 gene

1994 • 600 citations

Ecto-ATPases: Identities and Functions

1995 • 503 citations

GENETIC ANALYSIS OF THE MULTIDRUG TRANSPORTER

1995 • 469 citations

Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver.

1984 • 393 citations

Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport

1995 • 385 citations

The function of Gp170, the multidrug resistance gene product, in rat liver canalicular membrane vesicles

1989 • 329 citations

Functional polarity of the rat hepatocyte surface membrane. Isolation and characterization of plasma-membrane subfractions from the blood-sinusoidal, bile-Canalicular and contiguous surfaces of the hepatocyte

1975 • 308 citations

ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane. Role of the ATP-dependent transport system for glutathione S-conjugates.

1990 • 299 citations

Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes.

1995 • 230 citations

Defective ATP-dependent bile canalicular transport of organic anions in mutant (TR-) rats with conjugated hyperbilirubinemia.

1990 • 229 citations

Mechanisms of taurocholate transport in canalicular and basolateral rat liver plasma membrane vesicles. Evidence for an electrogenic canalicular organic anion carrier.

1984 • 225 citations

Leukotrienes as Mediators in Tissue Trauma

1985 • 214 citations

Rat liver canalicular membrane vesicles contain an ATP-dependent bile acid transport system.

1991 • 203 citations

Rat liver canalicular membrane vesicles. Isolation and topological characterization.

1983 • 202 citations

Molecular mechanisms of hepatic bile salt transport from sinusoidal blood into bile

1995 • 186 citations

A biochemical dissection of the functional polarity of the plasma membrane of the hepatocyte

1980 • 184 citations

ATP-dependent transport of taurocholate across the hepatocyte canalicular membrane mediated by a 110-kDa glycoprotein binding ATP and bile salt.

1991 • 176 citations

Cholestasis caused by inhibition of the adenosine triphosphate-dependent bile salt transport in rat liver

1994 • 165 citations

Primary Structure and Functional Expression of a cDNA Encoding the Bile Canalicular, Purine-specific Na+-Nucleoside Cotransporter

1995 • 162 citations

The biology of the bile canaliculus, 1993

1993 • 143 citations

Hereditary defect of hepatobiliary cysteinyl leukotriene elimination in mutant rats with defective hepatic anion excretion

1987 • 143 citations

mdr2 encodes P-glycoprotein expressed in the bile canalicular membrane as determined by isoform-specific antibodies.

1992 • 141 citations

The MDR superfamily of genes and its biological implications.

1994 • 140 citations

ATP-dependent taurocholate transport by rat liver canalicular membrane vesicles*1, *2

1991 • 136 citations

Role of membrane trafficking in plasma membrane solute transport

1994 • 135 citations

Motility of bile canaliculi in the living animal: implications for bile flow.

1991 • 131 citations

Taurocholate transport by rat liver canalicular membrane vesicles. Evidence for the presence of an Na+-independent transport system.

1984 • 119 citations

[34] Preparation of basolateral (sinusoidal) and canalicular plasma membrane vesicles for the study of hepatic transport processes

1990 • 73 citations

A nucleoside transporter is functionally linked to ectonucleotidases in rat liver canalicular membrane.

1992 • 71 citations

Functional reconstitution of the canalicular bile salt transport system of rat liver.

1988 • 69 citations

ATP-dependent transport systems in the canalicular membrane of the hepatocyte.

1995 • 60 citations

ATP-dependent phosphatidylcholine translocation in rat liver canalicular plasma membrane vesicles

1996 • 55 citations

Cell Surface Glycoproteins of Hepatocytes and Hepatoma Cells Identified by Monoclonal Antibodies

1986 • 51 citations

ATP-dependent transport of organic anions in secretory vesicles of Saccharomyces cerevisiae.

1994 • 30 citations