Response of human keratinocytes to extremely low concentrations of N-methyl-N′-nitro-N-nitrosoguanidine

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

DNA Repair and Mutagenesis

2006 • 4,725 citations

DNA repair and mutagenesis

1996 • 2,289 citations

Chemical Mutagens. Principles and Methods for Their Detection.

1974 • 1,473 citations

Poly(ADP-ribose) polymerase: a molecular nick-sensor

1994 • 790 citations

Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation.

1981 • 448 citations

Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction.

1982 • 398 citations

ADP-ribosylation of proteins. Enzymology and biological significance.

1987 • 374 citations

Drug and radiation resistance in spheroids: cell contact and kinetics

1994 • 268 citations

In vivo evidence for endogenous DNA alkylation damage as a source of spontaneous mutation in eukaryotic cells.

1993 • 177 citations

Self-destruction and tolerance in resistance of mammalian cells to alkylation damage

1992 • 173 citations

Regulation of Repair of Alkylation Damage in Mammalian Genomes

1993 • 164 citations

Formation and occurrence of nitrosamines in food.

1983 • 163 citations

Nonenzymatic methylation of DNA by S-adenosylmethionine in vitro

1982 • 161 citations

Alternative pathways for the in vivo repair of O6-alkylguanine and O4-alkylthymine in Escherichia coli: the adaptive response and nucleotide excision repair.

1988 • 139 citations

Inducibility of the DNA Repair Gene Encoding O⁶-Methylguanine- DNA Methyltransferase in Mammalian Cells by DNA-Damaging Treatments

1991 • 138 citations

Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments.

1991 • 111 citations

Relevance of urinary DNA adducts as markers of carcinogen exposure

1992 • 101 citations

7-Methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection.

1988 • 99 citations

Assessment of the risk of formation of carcinogenic N-nitroso compounds from dietary precursors in the stomach

1987 • 97 citations

Nuclear matrix associated DNA is preferentially repaired in normal human fibroblasts, exposed to a low dose of ultraviolet light but not in Cockayne's syndrome fibroblasts

1988 • 94 citations

Poly(ADP-ribose) molecules formed during DNA repair in vivo

1994 • 90 citations

Three Classes of DNA Strand Breaks Induced by X-irradiation and Internal β-rays

1986 • 83 citations

On Radiation, Paradigms, and Hormesis

1989 • 82 citations

Influence of ultrafast repair processes (independent of DNA polymerase I) on the yield of DNA single-strand breaks in Escherichia coli K-12 x-irradiated in the presence of or absence of oxygen.

1972 • 81 citations

Quantification of chemical mutagenesis in diploid human fibroblasts: Induction of azaguanine-resistant mutants by N-methyl-N′-nitro-N-nitrosoguanidine

1978 • 76 citations

The Relation between Reaction Kinetics and Mutagenic Action of Monofunctional Alkylating Agents in Higher Eukaryotic Systems: Interspecies Comparisons

1982 • 72 citations

Protein‐Bound Polymeric and Monomeric ADP‐Ribose Residues in Hepatic Tissues

1981 • 69 citations

Influence of Ultrafast Repair Processes (Independent of DNA Polymerase I) on the Yield of DNA Single-Strand Breaks in Escherichia coli K-12 X-Irradiated in the Presence or Absence of Oxygen

1972 • 63 citations

DNA repair kinetics after low doses of X-rays

1984 • 59 citations

Labeling methods for the study of poly- and mono(ADP-ribose) metabolism in cultured cells

1988 • 57 citations

The current evidence for an adaptive response to alkylating agents in mammalian cells, with special reference to experiments with in vitro cell cultures

1985 • 52 citations

Lack of induction of O⁶-methylguanine-DNA methyltransferase in mammalian cells treated with N-methyl-N' -nitro-N-nitrosoguanidine

1984 • 43 citations

Environmental mutagens that induce the adaptive response to alkylating agents in Escherichia coli

1991 • 43 citations

Effect of Cell-cycle Position and Dose on the Kinetics of DNA Double-strand Breakage Repair in X-irradiated Chinese Hamster Cells

1987 • 41 citations

Induction of proteins involved in the repair of alkylated bases in mammalian cells by DNA-damaging agents

1990 • 39 citations

Relationship between chemical damage of DNA and mutations in mammalian cells

1980 • 38 citations

Calcium Antagonist, TMB-8, Prevents the Induction of Adaptive Response by Hydrogen Peroxide or X-rays in Human Lymphocytes

1994 • 38 citations

Steady-state levels of 7-methylguanine increase in nuclear DNA of postmitotic mouse tissues during aging

1990 • 31 citations

Quantitative Measurement of DNA Strand Breaks and Repair in γ-Irradiated Human Leukocytes from Normal and Ataxia Telangiectasia Donors

1985 • 31 citations

DNA strand breaks and DNA repair response in lymphocytes after chronic in vivo exposure to very low doses of ionizing radiation in mice

1991 • 29 citations

Temperature dependence of the joining by T4 DNA ligase of termini produced by type II restriction endonucleases

1981 • 29 citations

Intranuclear localization of UV-induced DNA repair in human VA13 cells

1987 • 28 citations

A new highly selective physicochemical assay to measure NAD+ in intact cells

1986 • 21 citations

[9] Alkaline elution versus fluorescence analysis of DNA unwinding

1994 • 20 citations

DNA strand break metabolism in human lymphocytes: A reevaluation

1991 • 15 citations

The control of O6-methylguanine-DNA methyltransferase (MGMT) activity in mammalian cells: A pre-molecular view

1990 • 13 citations

DNA Excision Repair as a Component of Adaptation to Low Doses of Ionizing RadiationEscherichia Coli

1993 • 13 citations

Inhibiting the Repair of DNA Damage Induced by Gamma Irradiation in Rat Thymocytes

1994 • 10 citations

REPAIR OF DNA BREAKS INDUCED BY GAMMA RAYS AND FAST NEUTRONS IN CHINESE HAMSTER CELLS

1978 • 7 citations

Additional DNA long-range folding is an early process during stimulation of human lymphocytes

1990 • 7 citations

‘Periodical’ Pattern of Kinetics of DNA Strand Break Repair Following γ-irradiation of Human T1-cells

1987 • 6 citations