Assessment of the risk of formation of carcinogenic N-nitroso compounds from dietary precursors in the stomach

[Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats].

1967 • 1,408 citations

Organotrope carcinogene Wirkungen bei 65 verschiedenen N-Nitroso-Verbindungen an BD-Ratten

1967 • 1,336 citations

Carcinogenic Nitroso Compounds

1967 • 1,109 citations

Formation of N-nitroso compounds: Chemistry, kinetics, and in vivo occurrence

1975 • 759 citations

Nitrosamines as Environmental Carcinogens

1970 • 668 citations

In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis

1979 • 412 citations

Toxic liver injury and carcinogenesis. Methylation of rat-liver nucleic acids by dimethylnitrosamine in vivo

1962 • 399 citations

Quantitative estimation of endogenous nitrosation in humans by monitoring N-nitrosoproline excreted in the urine.

1981 • 346 citations

N-Nitroso compounds: occurrence, biological effects and relevance to human cancer

1985 • 316 citations

The Etiology of Gastric Cancer<subtitle>Intragastric Nitrosamide Formation and Other Theories</subtitle>

1983 • 284 citations

Nitrosation, diazotisation, and deamination

1961 • 256 citations

Nitrite in Human Saliva. Its Possible Relationship to Nitrosamine Formation23

1974 • 240 citations

Nitrous Acid And Nitrosation

1959 • 152 citations

DNA-damaging activity in vivo and bacterial mutagenicity of sixteen hydrazine derivatives as related quantitatively to their carcinogenicity.

1981 • 146 citations

N-Nitroso Compounds: Occurrence and Biological Effects

1984 • 141 citations

Primary and secondary amines in the human environment

1977 • 131 citations

Hepatic pathology in rats on low dietary levels of dimethylnitrosamine.

1967 • 127 citations

The mutagenicity of hydrazine and some of its derivatives

1977 • 124 citations

N-Nitroso Compounds in the Environment.

1975 • 120 citations

Comparative Study of the Carcinogenic Activity of Nitrosamines<xref ref-type="fn" rid="FN1">2</xref>

1961 • 109 citations

Environmental N-Nitroso Compounds: Analysis and Formation

1977 • 103 citations

N‐nitroso compounds: Their chemical andin vivoformation and possible importance as environmental carcinogens

1977 • 100 citations

Study of the Carcinogenicity of Large Doses of Dimethylnitramine, N-Nitroso-l-proline, and Sodium Nitrite Administered in Drinking Water to Rats23

1980 • 100 citations

N-nitroso Compounds Analysis, Formation and Occurrence

1981 • 92 citations

Daily Dietary Intakes of Nitrate, Nitrite and Volatile N-Nitrosamines in The Netherlands Using the Duplicate Portion Sampling Technique

1980 • 85 citations

Volatile Nitrosamines in Food

1980 • 70 citations

Occurrence and exposure to N-nitroso compounds and precursors.

1984 • 55 citations

Host Resistance to Gastric Adenocarcinomatosis in Three Strains of Rats Ingesting N-Methyl-N′-Nitro-N-Nitrosoguanidine

1973 • 48 citations

Safety evaluation of nitrosatable drugs and chemicals

1983 • 42 citations

The effect of substituents on the carcinogenicity of n-nitrosopyrrolidine in Sprague-Dawley rats.

1976 • 40 citations

Methylation of DNA in stomach and small intestine of rats after oral administration of methylamine and nitrite

1984 • 32 citations

Quantitative determination of the free amino acids and their derivatives in the common edible mushroom, Agaricus bisporus.

1981 • 29 citations

Carcinogenicity of N-nitrosopyrrolidine: Dose-response study in rats

1977 • 28 citations

Total nitroso compounds in gastric juice.

1982 • 24 citations

Rapid and selective induction of erythroleukemia in female Donryu rats by continuous oral administration of 1-ethyl-1-nitrosourea.

1976 • 22 citations

Endogenous synthesis of volatile nitrosamines: model calculations and risk assessment.

1982 • 21 citations

Occurrence, formation and precursors of N-nitroso compounds in the Japanese diet.

1980 • 21 citations

Comparison of nitrosocimetidine with nitrosomethylnitroguanidine in chronic feeding tests in rats.

1984 • 20 citations

Induction of tumors of peripheral nervous system in female Donryu rats by continuous oral administration of 1-methyl-1-nitrosourea.

1977 • 20 citations

Problems of Dose-Response Studies in Chemical Carcinogenesis with Special Reference to N-Nitroso Compounds

1979 • 18 citations

Effet d'une charge en nitrate sur le nitrite salivaire et gastrique chez l'homme

1978 • 17 citations

Occurrence of methylguanidine and agmatine, nitrosatable guanidino compounds, in foods

1978 • 17 citations

Methylation of liver DNA of rat and mouse by N-nitrosodimethylamine formed in vivo from dimethylamine and nitrite

1983 • 16 citations

In-vivo nitrosation, precancerous lesions and cancers of the gastrointestinal tract. On-going studies and preliminary results.

1984 • 16 citations

Fleisch und fleischwaren

1956 • 16 citations

Formation of volatile N-nitrosamines from food products, especially fish, under simulated gastric conditions.

1982 • 15 citations

Dose-response study of N-nitrosoproline formation in rats and a deduced kinetic model for predicting carcinogenic effects caused by endogenous nitrosation.

1983 • 15 citations

Identification of alkylureas after nitrosation-denitrosation of a bonito fish product, crab, lobster, and bacon

1980 • 15 citations

Measurement of endogenous n-nitrosation in rats and humans by monitoring urinary and faecal excretion of N-nitrosamino acids.

1982 • 14 citations

Das Nitrosaminproblem aus der Sicht des Lebensmittelchemikers

1972 • 14 citations

Carcinogenicity of N-nitroso-3-hydroxypyrrolidine and dose-response study with N-nitrosopiperidine in rats.

1980 • 14 citations

N-nitroso compounds in gastric juice and their relationship to gastroduodenal disease.

1982 • 12 citations

Analysis and occurrence of total N-nitroso compounds in the Japanese diet.

1984 • 12 citations

On the formation of N-nitrosopyrrolidine from potential precursors and nitrite.

1980 • 11 citations

Getreide und Getreidemahlprodukte

1967 • 10 citations

Kinetics of nitrosamine formation in mice following oral administration of trace-level precursors.

1980 • 8 citations

Induction of digestive-tract tumors in F344 rats by continuous oral administration of N-butyl-N-nitrosourea

1984 • 7 citations

N-nitrosamides of natural origin.

1982 • 7 citations

Studies on the effect of feeding nitrite and secondary amines to Wistar rats.

1976 • 6 citations

Effect of gastric surgery for benign peptic ulcer and ascorbic acid therapy on concentrations of nitrite and N-nitroso compounds in gastric juice.

1984 • 6 citations

Nitrosation of peptides.

1984 • 6 citations

Fleisch und Fleischwaren

1953 • 4 citations

Formation of alkylureas in the environment.

1982 • 2 citations

Nitrosation of piperazine in man.

1984 • 2 citations

Aminosäuren, Peptide, Proteine und andere Stickstoffverbindungen

1965 • 2 citations

Deleted Work

1955 • 0 citations