Clinical relevance of oxygen radicals in inflammatory bowel disease — Facts and fashion

Oxygen Radicals and Human Disease

1987 • 1,854 citations

Neutrophil-mediated mucosal injury

1988 • 445 citations

Metabolism of Arachidonic Acid in Acetic Acid Colitis in Rats

1985 • 259 citations

Role of reactive oxygen metabolites in experimental colitis.

1990 • 201 citations

The scavenging of oxidants by sulphasalazine and its metabolites

1987 • 155 citations

Chemotactic activity in inflammatory bowel disease

1987 • 148 citations

Effect of sulphasalazine and its metabolites on the generation of reactive oxygen species.

1987 • 135 citations

Treatment With 16, 16'-Dimethyl Prostaglandin E2 Before and After Induction of Colitis With Trinitrobenzenesulfonic Acid in Rats Decreases Inflammation

1989 • 130 citations

Diminished neutrophil function in Crohn's disease and ulcerative colitis identified by decreased oxidative metabolism and low superoxide dismutase content.

1988 • 101 citations

Oxygen-Derived Free Radical Generating Capacity of Polymorphonuclear Cells in Patients with Ulcerative Colitis

1989 • 92 citations

Closure of loop ileostomy after restorative proctocolectomy.

1990 • 48 citations

Superoxide production by Crohn's disease neutrophils.

1991 • 42 citations

Free Radicals in Gastroenterology: A Review

1988 • 42 citations

5-Aminosalicylic acid protects against ischemia/reperfusion-induced gastric bleeding in the rat

1988 • 34 citations

Inflammatory Bowel Diseases 1986

1987 • 30 citations

Phagocytes, toxic oxygen metabolites and inflammatory bowel disease: implications for treatment.

1990 • 21 citations

Use of 3,3,5,5-tetramethyl-1-pyrroline-1-oxide spin trap for the continuous flow ESR monitoring of hydroxyl radical generation in the ischemic and reperfused myocardium

1989 • 21 citations

[Recent knowledge of the pathophysiology of inflammation in Crohn disease and ulcerative colitis: possible sequelae for future treatment concepts].

1990 • 3 citations